Manufacturer: Alkem Laboratories Ltd
Salt Composition : Artemether(20mg), Lumefantrine(120mg)
Strip of 8 Tablet Dt
(Inclusive of all taxes)
Artisafe L 20 mg/120 mg Tablet DT works by killing the malaria-causing parasites thereby preventing further spread of the infection. It should be taken with food as this will help your body better absorb the medicine. Take it in the dose and duration advised by your doctor. Do not take more than the recommended dose, as this may have harmful effects on your body. Complete the full course of treatment to make sure the infection is treated completely.
Headache, loss of appetite, weakness, joint pain, or muscle pain are some of the common side effects associated with this medicine. You may also feel dizzy after taking this medicine. Inform your doctor if these persist or worsen.
efore taking this medicine, you should tell your doctor about all the medicines that you may be taking for any other health conditions. Pregnant or breastfeeding women should not take this medicine unless prescribed by the doctor, as it may be harmful effects on the developing baby.
Artisafe L 20 mg/120 mg Tablet DT is a combination of two antiparasitic medicines: Artemether and Lumefantrine, which treats malaria. These medicines work by increasing the levels of haeme in the blood, a substance toxic to the malarial parasite. This kills the parasite and stops the infection from spreading.
The pharmacokinetics of artemether and lumefantrine allow the two agents to act synergistically, achieving quick symptomatic relief with a high parasitological cure rate. Artemether has a rapid onset of action that reduces parasite biomass fast and resolves clinical symptoms.Lumefantrine is absorbed and cleared more slowly (terminal elimination half-life 3-4 days in malaria patients), and accumulates with successive doses, acting to prevent recrudescence by destroying any residual parasites that remain after artemether and DHA have been cleared from the body.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Artisafe L
Headache
Loss of appetite
Dizziness
Weakness
Joint pain
Muscle pain
If you are suffering from any of the following diseases, you should not take Artemether + Lumefantrine unless your doctor advises you to do so -
Heart Disease
Coronary Artery Disease (CAD)
Calcium Deficiency
Potassium Deficiency
Diabetes
Heart Disease
Coronary Artery Disease (CAD)
Diabetes
Calcium Deficiency
Potassium Deficiency
Artisafe L 20 mg/120 mg Tablet DT may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is not known whether it is safe to consume alcohol with Artisafe L 20 mg/120 mg Tablet DT. Please consult your doctor.
Artisafe L 20 mg/120 mg Tablet DT is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Use with caution
Below 9years: Contraindicated
Artemether and lumefantrine combination therapy is indicated for the treatment of acute uncomplicated malaria caused by Plasmodium falciparum, including malaria acquired in chloroquine-resistant areas. May also be used to treat uncomplicated malaria when the Plasmodium species has not been identified.
ARTEMETHER+LUMEFANTRINE may interact with other anti-malarial drugs (mefloquine, quinine, quinidine), drugs treating abnormal heart rhythms (flecainide, amiodarone, sotalol, procainamide, disopyramide), antipsychotics (pimozide, ziprasidone), macrolide antibiotics (erythromycin), antibiotics (ciprofloxacin, moxifloxacin, rifabutin, rifampin), fits medicines (carbamazepine, phenobarbital, phenytoin), antifungals (ketoconazole, itraconazole), HIV drugs (delavirdine, efavirenz, nelfinavir, ritonavir), antidepressants (clomipramine, amitriptyline, imipramine), blood pressure drugs (metoprolol), depression medicines (St. John's wort) and birth control pills.
Dissolve it in a glass of water before taking it. Artisafe L 20 mg/120 mg Tablet DT is to be taken with food.
Store below 30°C
If you miss a dose of Artisafe L 20 mg/120 mg Tablet DT, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
You have been prescribed Artisafe L 20 mg/120 mg Tablet DT for the treatment of acute uncomplicated malaria that is resistant to other antimalarial medications such as chloroquine.
Tips to reduce the chance of being bitten by mosquitoes:
Wear light-coloured and covered clothing when you are outside after sunset.
Use insect repellent creams or sprays on parts of your body not covered by clothing.
Spray to kill any mosquitoes that may have entered rooms in spite of screening.
Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
It should be taken with food or drinks rich in fat such as milk.
It may cause fatigue and dizziness. Use caution while driving or doing anything that requires concentration.
If you vomit within 1 hour of taking the tablets, take another dose.
Inform your doctor if you have kidney, liver or heart disease.
Take this medicine in the dose and duration as advised by your doctor. Dissolve it in a glass of water before taking it. Artisafe L 20 mg/120 mg Tablet DT is to be taken with food.
Q. How to take Artisafe L 20 mg/120 mg Tablet DT?
Take Artisafe L 20 mg/120 mg Tablet DT with food, exactly as prescribed by your doctor. This medicine is usually taken twice a day with a meal for 3 days, or as directed. On your first day of treatment, take your first dose with food, followed by your second dose 8 hours later. Then for the next 2 days, take one dose in the morning and one dose in the evening. Patients should be encouraged to resume normal eating as soon as food can be tolerated, since this improves the absorption of the medicine.
Q. Can I take Artisafe L 20 mg/120 mg Tablet DT while I am pregnant?
No, Artisafe L 20 mg/120 mg Tablet DT is considered to be harmful for women in their first trimester of pregnancy. The reason being, it increases the chances of fetal loss.
Q. Are there any specific contraindications associated with the use of Artisafe L 20 mg/120 mg Tablet DT?
The use of Artisafe L 20 mg/120 mg Tablet DT is considered to be harmful for patients with a known hypersensitivity to any of the active or inactive ingredients of the medicine. Caution is advised in patients with cases of severe malaria and in the first trimester of pregnancy.
Q. What should I know about the storage and disposal of Artisafe L 20 mg/120 mg Tablet DT?
It is advised to keep this medicine in the container it came in, tightly closed. It should be kept out of reach of children. Store it at room temperature and away from excess heat and moisture.
