Arvast 40mg Tablet (10'S)

Manufacturer: Intas Pharmaceuticals Ltd

Salt Composition : Rosuvastatin(40mg)


Arvast 40 Tablet is a widely prescribed medicine and is regarded as safe for long-term use. It can be taken with a meal or on an empty stomach. You can take it at any time of the day but try to take it at the same time each day. Most people with high cholesterol do not feel ill, but stopping your medicine may increase your cholesterol levels, making your condition worse and increasing your risk of heart disease and stroke.

It is important to have your cholesterol levels checked regularly. This medicine is only one part of the treatment program which should also include a healthy diet, regular exercise, smoking cessation, moderation of alcohol intake, and weight reduction. You can eat normally while taking this medicine, but try to avoid foods that are high in fat.

Common side effects of this medicine include muscle pain, weakness, nausea, headache, and stomach pain. These are usually mild and disappear after a short time. Consult your doctor if they persist or if you notice any yellowing of your eyes or get repeated or unexplained muscle pains.


Basic Information

Mechanism Of Action

Arvast 40 Tablet is a lipid-lowering medication (statin). It works by blocking an enzyme (HMG-CoA-reductase) that is required by the body to make cholesterol, thereby lowering "bad" cholesterol (LDL) and triglycerides and raising "good" cholesterol (HDL).


Pharmacokinets

 The oral bioavailability of rosuvastatin is 20%, which is comparable to atorvastatin, pravastatin and fluvastatin, and qualitatively higher than simvastatin and lovastatin. After a single oral dose the peak plasma concentration is reached at 5 hours.

Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Arvast

Muscle pain

Weakness

Headache

Abdominal pain

Dizziness

Joint pain

Nausea

Contra Indications

untreated decreased level of thyroid hormones

dehydration

alcoholism

a hemorrhage in the brain

liver failure

liver problems

acute kidney failure

bloody urine

a condition with muscle tissue breakdown called rhabdomyolysis

memory loss

high blood sugar

elevation of proteins in the urine

pregnancy

a patient who is producing milk and breastfeeding

muscle pain or tenderness with increase creatine kinase

metabolic syndrome x

immune-mediated necrotizing myopathy

chronic kidney disease stage 4 (severe)

chronic kidney disease stage 5 (failure)

kidney disease with likely reduction in kidney function

Child-Pugh class A liver impairment

Child-Pugh class B liver impairment

Child-Pugh class C liver impairment

Pregnancy Related Information

Arvast 40 Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.


Product And Alcohol Interaction

Caution is advised when consuming alcohol with Arvast 40 Tablet. Please consult your doctor.


Breast Feeding Related Information

Arvast 40 Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.


Children Related Information

Use with caution

Below 9years: Contraindicated

Indications

Rosuvastatin is a statin medication used as a lipid-lowering agent. The FDA-approved indications are homozygous familial hypercholesterolemia, hyperlipidemia, mixed dyslipidemia, primary dysbetalipoproteinemia, hypertriglyceridemia, and prevention of cardiovascular disease.

Interactions

atazanavir

clarithromycin

colchicine

cyclosporine

eltrombopag

fenofibrate

fenofibrate micronized

fenofibric acid

gemfibrozil

indinavir

ketoconazole

ledipasvir/sofosbuvir

lopinavir

mifepristone

nelfinavir

niacin

ombitasvir/paritaprevir/ritonavir and dasabuvir

ritonavir

saquinavir

Typical Dosage

Do not chew, crush or break it. Arvast 40 Tablet may be taken with or without food, but it is better to take it at a fixed time.

Storage Requirements

Store below 30°C


Effects Of Missed Dosage

If you miss a dose of Arvast 40 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not take two doses within 12 hours.


Effects Of Overdose

Consult a doctor before taking any medicines.

Expert Advice

Arvast 40 Tablet treats high cholesterol by lowering "bad" cholesterol (LDL) and triglycerides (fats). It should be taken in addition to regular exercise and low-fat diet.

In general, Arvast 40 Tablet is safe. It may cause diarrhea, gas or an upset stomach. If any of these happen to you, take it with food.

Inform your doctor if you experience fatigue, muscle weakness or muscle pain.

Your doctor may check your liver function before starting the treatment and regularly thereafter. Inform your doctor if you notice signs of liver problems such as stomach pains, unusually dark urine or yellowing of skin or eyes.

Inform your doctor if you have kidney disease, liver disease or diabetes before starting treatment with this medicine. If you are diabetic, monitor your blood sugar level regularly as Arvast 40 Tablet may cause an increase in your blood sugar level.

Do not take Arvast 40 Tablet if you are pregnant, planning a pregnancy or breastfeeding.

How To Use

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Arvast 40 Tablet may be taken with or without food, but it is better to take it at a fixed time.


FAQs

Q. For how long should I take Arvast 40 Tablet?

You may need to take Arvast 40 Tablet for life or for as long as directed by your doctor. The cholesterol levels will be maintained only till you are taking Arvast 40 Tablet. Stopping Arvast 40 Tablet without starting a different treatment may increase your cholesterol levels again. This medicine has only a few side effects and is usually considered safe if taken as directed by the doctor.

Q. Does Arvast 40 Tablet cause weight gain?

No, there is no evidence of Arvast 40 Tablet causing weight gain. If you are taking Arvast 40 Tablet and gaining weight, consult your doctor. The doctor may get some investigations done to know the reason for the weight gain.

Q. Does Arvast 40 Tablet make you tired?

Yes, Arvast 40 Tablet can make you feel tired. This is because it reduces the energy supply to the muscles in the body. However, the exact reason behind the phenomenon is unknown and needs more research. Tiredness usually occurs after exertion. Generalized fatigue is more often in people with heart disease or those suffering from liver illness. Arvast 40 Tablet also causes muscle damage which further worsens the tiredness. Therefore, you must consult your doctor if you feel tired while taking Arvast 40 Tablet.

Q. Should Arvast 40 Tablet be taken at night?

Arvast 40 Tablet should be taken once a day. It can be taken in the morning or at night or any time of the day, with or without food. Try taking this medicine at the same time every day. Doing this will help you remember to take it daily.

Q. What foods should be avoided when taking Arvast 40 Tablet?

Arvast 40 Tablet is used to decrease your blood cholesterol levels. Therefore, to seek the best results of this medicine, you should avoid foods that are high in calories like fried food and junk food. It is recommended to eat a low-fat and low-cholesterol diet. Be sure to follow all the exercise and dietary recommendations made by your doctor or dietician.

Q. How do I know whether Arvast 40 Tablet is beneficial for me or not?

All medicines have side effects, but the benefits of Arvast 40 Tablet in reducing cholesterol levels and the risk of heart attack and stroke are proven by a large number of studies. However, if you do have any concerns, then discuss it with your doctor. Your doctor will consider and explain to you the benefits of taking Arvast 40 Tablet versus the risks of not taking it at all.

Q. Can Arvast 40 Tablet cause memory loss?

Arvast 40 Tablet may cause memory loss in very rare cases. This is generally non-serious and may occur within 1 day of taking this medicine or may take years to appear. These symptoms may disappear within about 3 weeks of discontinuing Arvast 40 Tablet. However, you should consult your doctor if you experience this side effect as it could be due to some other reason.

Q. Can Arvast 40 Tablet cause muscle problems or muscle injury?

Yes, taking Arvast 40 Tablet can cause muscle problems or muscle injury. This is because of the reduced oxygen supply to the muscle cells which leads to fatigue, muscle pain, tenderness or muscle weakness. The soreness may be significant enough to interfere with your daily activities. Do not take it lightly and consult your doctor to know about ways to prevent this and to avoid making it worse.

Q. Is it true that Arvast 40 Tablet can cause diabetes?

If you are at high risk of developing type 2 diabetes, taking Arvast 40 Tablet may slightly increase this risk. This is because Arvast 40 Tablet has the potential to cause a slight increase in your blood sugar levels. If you already have type 2 diabetes, your doctor may advise you to keep monitoring your blood sugar levels closely for the first few months. Tell your doctor if you find it harder to control your blood sugar.