Manufacturer: Glenmark Pharmaceuticals Ltd
Salt Composition : Guaifenesin(50mg), Terbutaline(1.25mg), Bromhexine(2mg)
Ascoril SF Expectorant is taken with or without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your doctor know about all other medications you are taking as some may affect, or be affected by this medicine.
The most common side effects are nausea, diarrhea, bloating, indigestion, vomiting, stomach pain, sweating, headache, skin rash, tremor, and increased heart rate. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. This medicine can also cause sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can make sleepiness worse.
Ascoril SF Expectorant is a combination of three medicines: Guaifenesin, Terbutaline and Bromhexine, which relieves cough with mucus. Guaifenesin is an expectorant which decreases the stickiness of mucus (phlegm) and helps in its removal from the airways. Terbutaline is a bronchodilator. It works by relaxing the muscles in the airways and widens the airways. Bromhexine is a mucolytic which thins and loosens mucus (phlegm), making it easier to cough out. Together, they make breathing easier.
Serum guaifenesin concentrations were determined and pharmacokinetic parameters calculated. Guaifenesin was rapidly absorbed (Tmax of 15 min) following oral administration. The Cmax was 681.3 ± 323.8 ng/mL and 1080 ± 732.8 following the first and last dose, respectively.The pharmacokinetics of terbutaline has been studied after subcutaneous adminsitration of a therapeutic dose of 250 microgram in 14 patients. Short absorption half-lives of about 7 min resulted in a fast uptake of the drug.Bromhexine hydrochloride is rapidly absorbed from the gastrointestinal tract and undergoes extensive first-pass metabolism in the liver. Its oral bioavailability is stated to be only about 20%. It is widely distributed to body tissues and is highly bound to plasma proteins.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Ascoril SF
Nausea
Diarrhea
Bloating
Indigestion
Vomiting
Stomach pain
Sweating
Dizziness
Headache
Skin rash
Hives
Tremors
Increased heart rate
Allergy
Asthma
Smoking Addiction
High Blood Pressure
Hyperthyroidism
Diabetes
Glaucoma
Ascoril SF Expectorant may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is not known whether it is safe to consume alcohol with Ascoril SF Expectorant. Please consult your doctor.
Information regarding the use of Ascoril SF Expectorant during breastfeeding is not available. Please consult your doctor.
Use with caution
Below 9years: Contraindicated
Guaifenesin+Terbutaline+Bromhexine is used in the treatment of cough with mucus.Guaifenesin is an expectorant which decreases the stickiness of mucus (phlegm) and helps in its removal from the airways. Terbutaline is a bronchodilator. It works by relaxing the muscles in the airways and widens the airways. Bromhexine is a mucolytic which thins and loosens mucus (phlegm), making it easier to cough out. Together, they make breathing easier.
BROMHEXINE+GUAIFENESIN+MENTHOL+TERBUTALINE may have interaction with medicines used to lower high blood pressure (propranolol), hormone (epinephrine), water pills (furosemide), anti-allergic drugs (promethazine), uterine stimulant (oxytocin), bronchodilators (formoterol, dyphylline), anti-sickness drug (ondansetron).
Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Ascoril SF Expectorant may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Ascoril SF Expectorant, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Ascoril SF Expectorant relieves cough accompanied with mucus that is associated with broncho-pulmonary disorders such as bronchitis, bronchial asthma and emphysema.
It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
If you are diabetic, monitor your blood glucose regularly while taking this medicine.
Inform your doctor if you have a history of thyroid or heart disease.
Stop taking Ascoril SF Expectorant and inform your doctor if your cough persists for more than 1 week, tends to recur, or is accompanied by a fever, rash or persistent headache.
Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Ascoril SF Expectorant may be taken with or without food, but it is better to take it at a fixed time.
Q. Will Ascoril SF Expectorant be more effective if taken in more than recommended dose?
No, taking a higher than the recommended dose may not be more effective, rather it may increase the chances of having some serious side effects and toxicity. If you experience increased severity of your symptoms, that are not relieved by the recommended doses, please consult your doctor for re-evaluation.
Q. What are the instructions for storage and disposal of Ascoril SF Expectorant?
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
