Manufacturer: Alchemist Life Science Ltd
Salt Composition : Acebrophylline(100mg)
Strip of 10 Capsule
(Inclusive of all taxes)
Amace Tablet is used to treat hypertension (high blood pressure). This is a combination of two medicines that controls blood pressure when a single medication is not effective. It helps to lower high blood pressure and thus reduces the chances of future heart attack and stroke.
You can take Amace Tablet at any time of day, with or without food, but it is best to take it at the same time each day. Keep taking it for as long as advised by your doctor. Even if you feel well, do not stop this medicine on your own because high blood pressure often has no symptoms. If you stop taking it, your condition may get worse. Keeping active with regular exercise, reducing your weight and eating a healthy diet will also help control your blood pressure. Follow your doctor’s advice while taking this medicine.
It may cause side effects like taste change, ankle swelling, headache, weakness, and tiredness. It may also cause dizziness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. This might raise the level of potassium in the blood, hence avoid potassium rich food or supplements. You may be asked for regular monitoring of blood pressure, kidney function, and electrolytes level while on the treatment.
Before taking it, let your doctor know if you have any liver or kidney problems. Pregnant or breastfeeding women should also consult their doctor for advice before taking this medicine. You also need to tell your doctor what other medicines you are taking especially those used to treat high blood pressure or heart conditions.
Acebrophylline modifies mucus secretion by lowering viscosity of 'gel' phase, increasing 'sol' phase and increases mucociliary clearance by augmenting ciliary motility. Acebrophylline inhibits intracellular phosphodiesterase and facilitates bronchial muscles relaxation by increasing cAMP levels
Pharmacokinetics: After oral administration of acebrophylline, the two components of the molecule ambroxol and theophylline-7-acetic acid are released in the stomach and absorbed in the intestine, reaching optimal concentrations of ambroxol within 2hrs and of theophylline-7-acetic acid after 1 hr.
Decreased blood pressure
Sleepiness
Taste change
Ankle swelling
Headache
Flushing (sense of warmth in the face, ears, neck and trunk)
Tiredness
Palpitations
Increased potassium level in blood
Cough
Upset stomach
If you are allergic to acebrophylline, theophylline or similar medicines.
If you have problems with your kidney or liver.
If you have any heart disease such as low blood pressure, unstable blood pressure or abnormal heart rate.
Amace Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
It is unsafe to consume alcohol with Amace Tablet.
Amace Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Acebrophylline is prescribed to reduce the irritation, swelling, and narrowing of the bronchial tubes in patients with asthma, severe or chronic bronchitis, chronic obstructive pulmonary disease (COPD)and tightness of the chest
Drug-Drug Interaction: ACEBROPHYLLINE may interact with water pills (furosemide), medicines used to treat gout (allopurinol), antacid (cimetidine), antibiotics (ciprofloxacin, erythromycin, amoxicillin, doxycycline), drugs used to lower high blood pressure (diltiazem, verapamil), heart-related medicines (isoprenaline),
Swallow it as a whole. Do not chew, crush or break it. Amace Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Amace Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines
You have been prescribed Amace Tablet for the treatment of high blood pressure.
Lowering blood pressure reduces chance of future heart attack & strokes.
It may cause dizziness. Get up slowly when rising from a sitting or lying position.
Do not take Amace Tablet if you are pregnant or planning for pregnancy.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Amace Tablet may be taken with or without food, but it is better to take it at a fixed time.
