Manufacturer: Abbott
Salt Composition : Atazanavir(300mg), Ritonavir(100mg)
Ataclip 300 mg/100 mg Tablet should be used in the dose and duration as advised by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. Take it with food, as this increases the absorption of the medicine into the body. Some of the common side effects include nausea, decreased appetite, weakness and headache. Please consult your doctor if these side effects persist for a longer duration.
Atazanavir binds to the protease active site and inhibits the activity of the enzyme. This inhibition prevents cleavage of the viral polyproteins resulting in the formation of immature non-infectious viral particles. Protease inhibitors are almost always used in combination with at least two other anti-HIV drugs.
Atazanavir is rapidly absorbed and administration of a single dose of atazanavir with a light meal resulted in a 70% increase in area under the plasma concentration-time curve (AUC); therefore atazanavir should be taken with food. Atazanavir is 86% bound to human serum protein independently of concentration.
The pharmacokinetics of ritonavir are relatively linear after multiple doses, with apparent oral clearance averaging 7 to 9 L/h. In vitro, ritonavir is a potent inhibitor of CYP3A.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Ataclip
Rash
Headache
Dizziness
Vomiting
Crystals in urine
Nausea
Abdominal pain
Indigestion
Paresthesia (tingling or pricking sensation)
Throat pain
Increased liver enzymes
Diarrhea
Blood in urine
Peripheral neuropathy (tingling and numbness of feet and hand)
Cough
Taste change
Hypercholesterolemia (high cholesterol)
Increased triglyceride level in blood
Protein in urine
diabetes.
high cholesterol.
high amount of triglyceride in the blood.
a type of joint disorder due to excess uric acid in the blood called gout.
hemophilia.
a low supply of oxygen rich blood to the heart.
cardiomyopathy, a disease of the heart muscle.
complete heart block.
Information regarding the use of Ataclip 300 mg/100 mg Tablet during pregnancy is not available. Please consult your doctor.
Caution is advised when consuming alcohol with Ataclip 300 mg/100 mg Tablet. Please consult your doctor.
Information regarding the use of Ataclip 300 mg/100 mg Tablet during breastfeeding is not available. Please consult your doctor.
Atazanavir is used along with other medications to treat human immunodeficiency virus (HIV) infection in adults and children who are at least 3 months of age and weigh at least 22 lb (10 kg). Atazanavir is in a class of medications called protease inhibitors. It works by decreasing the amount of HIV in the blood.
Drug-Food Interactions: No interactions found. Drug-Disease Interactions: ATAZANAVIR+RITONAVIR should not be used in patients with liver disease, hepatitis B or C (liver infections), haemophilia (bleeding disorder), erectile dysfunction, diabetes, gall stones, and kidney disease.
Do not chew, crush or break it. Ataclip 300 mg/100 mg Tablet
Store below 30°C
If you miss a dose of Ataclip 300 mg/100 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Atazanavir
Atazanavir should be taken with food.
Do not skip any doses and finish the full course of treatment even if you feel better.
Do not take antacids an hour before or two hours after taking Atazanavir.
It may cause dizziness or sleepiness. Do not drive or do anything that requires concentration until you know how it affects you.
Stop taking medications (prescribed for erectile dysfunction) like sildenafil or tadalafil while on treatment with this medicine.
Your doctor may check your liver function regularly. Inform your doctor if you develop abdominal pain, loss of appetite darkened urine or yellowing of the eyes or skin (jaundice).
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Ritonavir
Ritonavir should be taken with food.
Do not skip any doses and finish the full course of treatment even if you feel better.
Do not take antacids an hour before or two hours after taking Ritonavir.
It may cause dizziness or sleepiness. Do not drive or do anything that requires concentration until you know how it affects you.
Stop taking medications (prescribed for erectile dysfunction) like sildenafil or tadalafil while on treatment with this medicine.
Your doctor may check your liver function regularly. Inform your doctor if you develop abdominal pain, loss of appetite darkened urine or yellowing of the eyes or skin (jaundice).
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ataclip 300 mg/100 mg Tablet is to be taken with food.
Atazanavir
Q. What is Atazanavir used for?
Atazanavir is used in combination with other anti-retroviral medicines for the treatment of human immunodeficiency virus (HIV-1) infection
Q. Does Atazanavir cause hyperbilirubinemia?
Yes, hyperbilirubinemia (an increase in the level of bilirubin in the blood) is a known side effect of Atazanavir.
Q. How does Atazanavir work?
Atazanavir belong to a group of medications called azapeptide HIV-1 protease inhibitor. It inhibits some viral polypeptides in the HIV-1 infected cells of the body and inhibits and prevents maturation of virus in the cells. Atazanavir does not cure HIV infections; it decreases the risks of developing acquired immunodeficiency syndrome (AIDS) and other HIV-related illnesses due to compromised immunity
Q. Does Atazanavir cause lipodystrophy?
Yes, lipodystrophy (changes in body fat - build up or loss of body fat) is a known side effect of Atazanavir
Ritonavir
Q. What is Ritonavir used for?
It is used along with other medication for treating human immunodeficiency virus (HIV) infection. It does not completely cure HIV or AIDS
Q. Why is ritonavir used along with lopinavir?
Ritonavir is available with lopinavir as a fixed dose combination as it improves the availability of lopinavir which helps in increasing activity against HIV
Q. Is ritonavir a protease inhibitor?
Ritonavir, a protease inhibitor
Q. How does Ritonavir work and what does it inhibit?
Ritonavir belongs to a class of medication called protease inhibitors. It inhibits protease enzymes from breaking down proteins and thus prevents HIV from multiplying inside the body. It does not cure HIV completely but reduces the chances of getting acquired immunodeficiency syndrome (AIDS) and HIV related infections or cancer
