Atazor 300mg Capsule (30'S)

Manufacturer: Emcure Pharmaceuticals Ltd

Salt Composition : Atazanavir(300mg)

Prescription
Prescription Required: Consult the Doctor & Get Your ePrescription

Atazor 300 Capsule should be taken with food, as this increases the absorption of the medicine into the body. You should take it in the dose and duration as advised by your doctor. Taking it at the same time every day will help you to remember to take it. Do not stop taking it until you have finished the complete course, even when you feel better. If you stop taking this medicine too early then infection may return or worsen.

The most common side effects of this medicine include rash, headache, dizziness, and vomiting. These are usually mild but let your doctor know if they bother you or last more than a few days.

Before using it, you should tell your doctor if you are allergic to any antibiotics or have any kidney or liver problems. You should also let your doctor know all other medicines you are taking as they may affect, or be affected by this medicine. Pregnant and breastfeeding mothers should consult their doctor before using it. Your doctor may monitor your liver function while taking this medication.


Basic Information

Mechanism Of Action

Atazanavir binds to the active site HIV protease and prevents it from cleaving the pro-form of viral proteins into the working machinery of the virus. If the HIV protease enzyme does not work, the virus is not infectious, and no mature virions are made.


Pharmacokinets

Atazanavir is rapidly absorbed and administration of a single dose of atazanavir with a light meal resulted in a 70% increase in area under the plasma concentration-time curve (AUC); therefore atazanavir should be taken with food. Atazanavir is 86% bound to human serum protein independently of concentration.


Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Atazor

Rash

Headache

Dizziness

Vomiting

Abdominal pain

Blood in urine

Cough

Crystals in urine

Diarrhea

Indigestion

Hypercholesterolemia (high cholesterol)

Increased liver enzymes

Increased triglyceride level in blood

Nausea

Paresthesia (tingling or pricking sensation)

Peripheral neuropathy (tingling and numbness of feet and hand)

Protein in urine

Taste change

Throat pain


Contra Indications

chronic hepatitis B.

chronic hepatitis C.

diabetes.

increased blood acidity due to high levels of lactic acid.

hemophilia.

atrioventricular block, a type of slow heart rhythm disorder.

gallstones.

end-stage renal disease.


Pregnancy Related Information

Atazor 300 Capsule is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.


Product And Alcohol Interaction

It is not known whether it is safe to consume alcohol with Atazor 300 Capsule. Please consult your doctor.


Breast Feeding Related Information

Atazor 300 Capsule is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.


Indications

Atazanavir is used along with other medications to treat human immunodeficiency virus (HIV) infection in adults and children who are at least 3 months of age and weigh at least 22 lb (10 kg). Atazanavir is in a class of medications called protease inhibitors. It works by decreasing the amount of HIV in the blood.

Interactions

heart block.

nephrolithiasis.

renal impairment.

hemophilia.

liver disease.

PKU.

hyperglycemia.

hyperlipidemia.


Typical Dosage

Atazor 300 Capsule is to be taken with food.


Storage Requirements

Store below 30°C


Effects Of Missed Dosage

If you miss a dose of Atazor 300 Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.


Effects Of Overdose

Consult a doctor before taking any medicines.


Expert Advice

Atazor 300 Capsule should be taken with food.

Do not skip any doses and finish the full course of treatment even if you feel better.

Do not take antacids an hour before or two hours after taking Atazor 300 Capsule.

It may cause dizziness or sleepiness. Do not drive or do anything that requires concentration until you know how it affects you.

Stop taking medications (prescribed for erectile dysfunction) like sildenafil or tadalafil while on treatment with this medicine.

Your doctor may check your liver function regularly. Inform your doctor if you develop abdominal pain, loss of appetite darkened urine or yellowing of the eyes or skin (jaundice).

Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.


How To Use

Take this medicine in the dose and duration as advised by your doctor. Atazor 300 Capsule is to be taken with food.


FAQs

Q. What is Atazor 300 Capsule used for?

Atazor 300 Capsule is used in combination with other anti-retroviral medicines for the treatment of human immunodeficiency virus (HIV-1) infection

Q. Does Atazor 300 Capsule cause hyperbilirubinemia?

Yes, hyperbilirubinemia (an increase in the level of bilirubin in the blood) is a known side effect of Atazor 300 Capsule.

Q. How does Atazor 300 Capsule work?

Atazor 300 Capsule belong to a group of medications called azapeptide HIV-1 protease inhibitor. It inhibits some viral polypeptides in the HIV-1 infected cells of the body and inhibits and prevents maturation of virus in the cells. Atazor 300 Capsule does not cure HIV infections; it decreases the risks of developing acquired immunodeficiency syndrome (AIDS) and other HIV-related illnesses due to compromised immunity

Q. Does Atazor 300 Capsule cause lipodystrophy?

Yes, lipodystrophy (changes in body fat - build up or loss of body fat) is a known side effect of Atazor 300 Capsule