Manufacturer: Algen Healthcare Limited
Salt Composition : Ampicillin(250mg), Sulbactam(125mg)
Aticef 250 mg/125 mg Tablet is best-taken on an empty stomach. Take it preferably half to one hour before food. You should take it in the dose and duration as advised by your doctor. The dose will depend on the condition you are being treated for, but you should always complete a full course of the medicine even if you feel better. If you stop taking it early, some bacteria may survive and the infection may come back.
Some common side effects of this medicine include nausea, vomiting, diarrhea, and rash. You should contact your doctor if these side effects do not resolve with time and persist for a longer duration.
Before using it, you should tell your doctor if you are allergic to any antibiotics or have any kidney or liver problems. Your doctor may change the dose or prescribe a different medicine. This medicine is generally regarded as safe to use during pregnancy if used under a doctor’s supervision. However, you should consult with your doctor if you are breastfeeding.
Aticef 250 mg/125 mg Tablet is a combination of two medicines: Ampicillin and Sulbactam. Ampicillin is an antibiotic. It works by preventing the formation of the bacterial protective covering which is essential for the survival of bacteria. Sulbactam is a beta-lactamase inhibitor which reduces resistance and enhances the activity of Ampicillin against bacteria.
Ampicillin is well-absorbed from the GI tract (though food reduces its absorption), and reaches peak concentrations in one to two hours. The bioavailability is around 62% for parenteral routes. Unlike other penicillins, which usually bind 60–90% to plasma proteins, ampicillin binds to only 15–20%.Sulbactam, a new beta-lactamase inhibitor, has pharmacokinetic characteristics in humans similar to those of ampicillin and amoxicillin. Its half-life in humans is approximately 1 h.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Aticef
Rash
Vomiting
Nausea
Diarrhea
Abdominal pain
Headache
Fungal infection
Itching
Anemia (low number of red blood cells)
Low blood platelets
Increased white blood cell count (eosinophils)
Injection site reactions (pain, swelling, redness)
Increased bilirubin in the blood
Serve side effects of Aticef
Toxic epidermal necrolysis
Stevens-Johnson syndrome
Erythema multiforme
Angioedema (swelling of deeper layers of skin)
Urticaria
Increased liver enzymes
Abnormal liver function
Pseudomembranous colitis
Asthma
Diabetes
Hypersensitivity
Kidney or gastrointestinal disease
Runny nose due to allergy
Aticef 250 mg/125 mg Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Consuming alcohol with Aticef 250 mg/125 mg Tablet does not cause any harmful side effects.
Aticef 250 mg/125 mg Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Use with caution
Below 9years: Contraindicated
The combination of ampicillin and sulbactam injection is used to treat certain infections caused by bacteria, including infections of the skin, female reproductive organs, and abdomen (stomach area). Ampicillin is in a class of medications called penicillin-like antibiotics. It works by stopping the growth of bacteria.
Allopurinol
Probenecid
Tetracyclines
Do not chew, crush or break it. Aticef 250 mg/125 mg Tablet is to be taken empty stomach.
Store below 30°C
If you miss a dose of Aticef 250 mg/125 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines
You have been prescribed this combination medicine to treat bacterial infections even if they have developed resistance.
Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
Diarrhea may occur as a side effect. Taking probiotics along with Aticef 250 mg/125 mg Tablet may help. Talk to your doctor if you notice bloody stools or develop abdominal cramps.
Stop taking Aticef 250 mg/125 mg Tablet and inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking it.
Do not use leftover medicine for treating any infection in the future. Always consult your doctor before taking any antibiotic.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Aticef 250 mg/125 mg Tablet is to be taken empty stomach.
Q. What is Aticef 250 mg/125 mg Tablet?
Aticef 250 mg/125 mg Tablet is a combination of two medicines. It is used to treat bacterial infections like tonsillitis, sinusitis, otitis media, respiratory tract infections, urinary tract infections, boils, abscesses, cellulitis, wound infection, bone infection and oral cavity infections. The medicine works by killing the harmful bacteria that cause infection.
Q. Is it safe to use Aticef 250 mg/125 mg Tablet?
Aticef 250 mg/125 mg Tablet is safe to use when taken as advised by the doctor. However, in some patients, it may cause common side effects like diarrhea, nausea, vomiting, rash, allergic reaction, etc. If you experience any persistent problem while taking this medicine, inform your doctor as soon as possible.
Q. Are there any specific cautions associated with the use of Aticef 250 mg/125 mg Tablet?
The use of Aticef 250 mg/125 mg Tablet is considered to be harmful for patients with known allergy to penicillins or any other ingredient of the medicine. It should not be used in patients with a history of liver disease. Therefore, inform your doctor if you are allergic to any medicines.
Q. Can the use of Aticef 250 mg/125 mg Tablet cause contraceptive failure?
Yes, the use of Aticef 250 mg/125 mg Tablet can lower the efficacy of birth control pills. Consult your doctor and seek advice regarding the use of other methods of contraception (e.g., condom, diaphragm, spermicide) while you are taking Aticef 250 mg/125 mg Tablet.
Q. Can I take a higher than the recommended dose of Aticef 250 mg/125 mg Tablet?
No, Aticef 250 mg/125 mg Tablets should be taken at the recommended dose only. Overdose of Aticef 250 mg/125 mg Tablet can increase the risks of side effects. Aticef 250 mg/125 mg Tablet may take some time to show its full effect and treat your infection, be patient. If you are experiencing increased severity of your symptoms, please consult your doctor for re-evaluation.
Q. What are the instructions for the storage and disposal of Aticef 250 mg/125 mg Tablet?
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Q. Can I stop taking Aticef 250 mg/125 mg Tablet when my symptoms are relieved?
No, do not stop taking Aticef 250 mg/125 mg Tablet before completing the full course of the treatment, even if you feel better. Your symptoms may improve before the infection is completely cured, but the medicine may still be showing beneficial effects. Therefore, it is important to take this medicine for the duration advised by the doctor.
Q. Can Aticef 250 mg/125 mg Tablet cause an allergic reaction?
Yes, Aticef 250 mg/125 mg Tablet can cause an allergic reaction. It is considered to be harmful for patients with known allergy to penicillins. Get emergency medical help if you have any signs of allergic reaction like hives, difficulty breathing, swelling of your face, lips, tongue or throat.
Q. Can the use of Aticef 250 mg/125 mg Tablet cause diarrhea?
Yes, the use of Aticef 250 mg/125 mg Tablet can cause diarrhea. It is an antibiotic which kills the harmful bacteria. In addition to that, it can also affect the helpful bacteria in your stomach or intestine and cause diarrhea. In case you experience diarrhea, drink plenty of water or other fluids. Talk to your doctor if diarrhea persists and you notice any signs of dehydration, like less frequency of urination with dark colored and strong-smelling urine. Do not take any other medicine without consulting a doctor.
