Manufacturer: Centaur Pharmaceuticals Pvt Ltd
Salt Composition : Tetrabenazine(25mg)
Strip of 10 Tablet
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Atrest 25 Tablet should be taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember. This medication mustn't be stopped suddenly without talking to your doctor as it may worsen your symptoms. However, discontinue this medicine immediately if you experience neuroleptic malignant syndrome, characterized by fever, muscle rigidity, and altered consciousness or seizures.
Some common side effects of this medicine include nausea, insomnia(difficulty sleeping), anxiety, fatigue, akathisia (restlessness and inability to stay still), and depression. It also causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts while taking this medicine.
This medication is thought to work by decreasing the amount of certain natural substances in the brain (monoamines such as dopamine, serotonin, and norepinephrine), which are involved with nerve and muscle function. Tetrabenazine belongs to a class of drugs called monoamine depletors.
Tetrabenazine belongs to a class of medicines called monoamine depletors. It is used for treating involuntary movements (chorea) caused by Huntington disease. It works by reducing the amount of some chemicals in the brain such as norepinephrine, dopamine, serotonin.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Atrest
Nausea
Insomnia (difficulty in sleeping)
Anxiety
Fatigue
Sleepiness
Akathisia (inability to stay still)
Depression
Tetrabenazine is contraindicated in patients with hepatic impairment (See CONTRAINDICATIONS and CLINICAL PHARMACOLOGY - Special Populations) and in patients with untreated or inadequately treated depression or who are actively suicidal.
Atrest 25 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Atrest 25 Tablet may cause excessive drowsiness with alcohol.
Atrest 25 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Tetrabenazine is used to decrease the uncontrollable movements (chorea) caused by Huntington's disease. However, it is not a cure for the disease. Reducing the chorea will help you take part in more of your normal daily activities.
cardiac arrhythmias.
depression.
hepatic impairment.
Huntington's disease.
dysphagia.
hyperprolactinemia.
hypotension.
Do not chew, crush or break it. Atrest 25 Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
You have been prescribed Atrest 25 Tablet to help control movement disorders such as in Huntington’s disease.
Be cautious while driving or doing anything that requires concentration as Atrest 25 Tablet can cause dizziness and sleepiness.
Inform your doctor if you experience symptoms such as high fever, sweating, muscle stiffness, and faster breathing. These may be due to a rare side effect known as the neuroleptic malignant syndrome.
Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.
Do not stop taking Atrest 25 Tablet without talking to your doctor first as it may cause worsening of symptoms.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Atrest 25 Tablet may be taken with or without food, but it is better to take it at a fixed time.
Q. Can Atrest 25 Tablet be crushed?
No, Atrest 25 Tablet should not be crushed, cut, or chewed. It needs to be swallowed as a whole. But if you cannot swallow the whole tablet, tell your doctor who will probably prescribe you another medicine.
Q. Is Atrest 25 Tablet an antipsychotic?
Atrest 25 Tablet is not an antipsychotic. It belongs to the vesicular monoamine transporter 2 (VMAT2) inhibitor class of medicines. It works by changing the activity of some natural substances in the brain that affect muscles and nerves.
Q. What is the most important information that I should know about Atrest 25 Tablet?
Atrest 25 Tablet may increase the risk of depression or suicidal thoughts in patients with Huntington’s disease. Huntington’s disease is an inherited disease that causes the progressive breakdown of nerve cells in the brain. Therefore, you should not take Atrest 25 Tablet if you have Huntington’s disease along with depression.
Q. What should I avoid while taking Atrest 25 Tablet?
Sleepiness is a common side effect of Atrest 25 Tablet. Therefore, you should avoid driving or operating heavy machinery if you feel sleepy while taking Atrest 25 Tablet.
