Manufacturer: Avinash Health Products Pvt Ltd
Salt Composition : Gliclazide(80mg), Metformin(500mg)
Strip of 10 Tablet
(Inclusive of all taxes)
Aviglic MF 80 mg/500 mg Tablet should be taken with food. Take it regularly at the same time each day to get the most benefit. Your doctor will decide what dose is best for you and this may change from time to time according to how it is working according to your blood sugar levels. Keep taking this medicine, even if you feel well or your blood sugar levels are controlled. If you stop it without consulting your doctor, your blood sugar levels could rise and put you at risk of kidney damage, blindness, nerve problems and loss of limbs. Remember that it is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. Your lifestyle plays a big part in controlling diabetes.
Aviglic MF 80 mg/500 mg Tablet is a combination of two antidiabetic medicines: Gliclazide and Metformin. Gliclazide is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose.
A single oral dose of 40 to 120 mg of gliclazide results in a Cmax of 2.2 to 8.0 µg/ml within 2 to 8 hours. Tmax and cmax are increased after repeated gliclazide administration. Steady state concentration is achieved after 2 days administration of 40 to 120 mg of gliclazide.
Metformin is rapidly distributed following absorption and does not bind to plasma proteins. No metabolites or conjugates of metformin have been identified. The absence of liver metabolism clearly differentiates the pharmacokinetics of metformin from that of other biguanides, such as phenformin.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Aviglic MF
Hypoglycemia (low blood glucose level)
Headache
Nausea
Dizziness
Diarrhea
Flatulence
Contraindicated in patients with diabetic-ketoacidosis, severe liver and kidney impairment, and hypersensitivity.
Renal dysfunction.
Congestive cardiac failure needing drug treatment.
Hypersensitivity to metformin.
Acute or chronic metabolic acidosis.
Impaired hepatic function.
Aviglic MF 80 mg/500 mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
It is unsafe to consume alcohol with Aviglic MF 80 mg/500 mg Tablet.
Aviglic MF 80 mg/500 mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Aviglic MF 80 mg/500 mg Tablet is a combination of two medicines: Gliclazide and Metformin. This medicine is used in the treatment of type 2 diabetes mellitus (DM). It improves blood glucose levels in adults when taken along with proper diet and regular exercise.
Drug-Drug interactions: Before taking AVIGLIC MF inform to your doctor, if you are taking any of these medicines: beta-blockers such as metoprolol, atenolol, angiotensin converting enzyme inhibitors such as captopril, enalapril (treats high blood pressure) warfarin (treats blood clot)
Do not chew, crush or break it. Aviglic MF 80 mg/500 mg Tablet
Store below 30°C
If you miss a dose of Aviglic MF 80 mg/500 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Monitor your blood sugar level regularly while you are taking this medicine.
It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic.
Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as Aviglic MF 80 mg/500 mg Tablet may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.
Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Aviglic MF 80 mg/500 mg Tablet is to be taken with food.
Q. What is Aviglic MF 80 mg/500 mg Tablet?
Aviglic MF 80 mg/500 mg Tablet is a combination of two medicines: Gliclazide and Metformin. This medicine is used in the treatment of type 2 diabetes mellitus (DM). It improves blood glucose levels in adults when taken along with proper diet and regular exercise. Gliclazide lowers the blood glucose levels by increasing the release of insulin from the pancreas. Metformin works by lowering the glucose production in the liver and improving insulin sensitivity. This combination is not indicated for the treatment of Type 1 DM.
Q. What are the possible side effects of Aviglic MF 80 mg/500 mg Tablet?
The use of Aviglic MF 80 mg/500 mg Tablet is associated with common side effects. These side effects may include hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, headache and upper respiratory tract infection. Its use can also lead to serious but rare side effects like lactic acidosis. On long-term use, it can also lead to vitamin B12 deficiency.
Q. Can the use of Aviglic MF 80 mg/500 mg Tablet cause hypoglycemia?
Yes, the use of Aviglic MF 80 mg/500 mg Tablet can cause hypoglycemia (low blood sugar level). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate and feeling anxious or shaky. It happens more often if you miss or delay your food, drink alcohol, over-exercise or take other antidiabetic medicine along with it. So, regular monitoring of blood sugar level is important. Always keep glucose tablets, honey or fruit juice with you.
Q. Can the use of Aviglic MF 80 mg/500 mg Tablet cause lactic acidosis?
Yes, the use of Aviglic MF 80 mg/500 mg Tablet can lead to lactic acidosis. It is a medical emergency which is caused by increased levels of lactic acid in the blood. It is also known as MALA (Metformin associated lactic acidosis). It is a rare side effect associated with the use of metformin. It is avoided in patients with underlying kidney disease, old age patients or who take large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, feeling of cold in arms and legs, difficulty in breathing, nausea, vomiting, stomach pain or slow heart rate. If you have these symptoms, stop taking Aviglic MF 80 mg/500 mg Tablet and immediately consult your doctor.
