Manufacturer: Avis Lifecare Pvt Ltd
Salt Composition : Glimepiride(1mg), Metformin(500mg)
Strip of 10 Tablet
(Inclusive of all taxes)
Axiglim M 1mg Tablet should be taken with food. Take it regularly at the same time each day to get the most benefit. Your doctor will decide what dose is best for you and this may change from time to time according to how it is working according to your blood sugar levels. You should not take it if you have type 1 diabetes mellitus, if you have diabetic ketoacidosis (high levels of acid in your blood), or if you have severe kidney or liver disease. Before taking this medicine, tell your doctor if you have ever had heart disease. It may not be suitable. Pregnant or breastfeeding women should also consult their doctor before taking it. Your blood sugar levels should be checked regularly and your doctor may also advise blood tests to monitor your blood cell counts and liver function.
Both of these components are known to increase the insulin sensitivity of the body (allows the cells of the body to use blood glucose more effectively, reducing blood sugar).
Glimepiride is completely metabolized by oxidative biotransformation after either an IV or oral dose. The major metabolites are the cyclohexyl hydroxy methyl derivative (M1) and the carboxyl derivative (M2). Cytochrome P450 2C9 has been shown to be involved in the biotransformation of glimepiride to M1.
Metformin is rapidly distributed following absorption and does not bind to plasma proteins. No metabolites or conjugates of metformin have been identified. The absence of liver metabolism clearly differentiates the pharmacokinetics of metformin from that of other biguanides, such as phenformin.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Axiglim M
Hypoglycemia (low blood glucose level)
Headache
Nausea
Diarrhea
Flatulence
low blood sugar.
pituitary hormone deficiency.
a condition where the adrenal glands produce less hormones called Addison's disease.
glucose-6-phosphate dehydrogenase (G6PD) deficiency.
hepatic porphyria.
a type of blood disorder where the red blood cells burst called hemolytic anemia.
Axiglim M 1mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is unsafe to consume alcohol with Axiglim M 1mg Tablet.
Axiglim M 1mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Axiglim M 1mg Tablet is a combination of two medicines: Glimepiride and Metformin. This medicine is used in the treatment of type 2 diabetes mellitus (DM). It improves blood glucose levels in adults when taken along with proper diet and regular exercise.
Glimepiride increases the risk of dangerously low blood sugar levels. People who take this medication must, therefore, check their blood sugar levels regularly.
Interactions
atypical antipsychotics (e.g. olanzapine and clozapine)
thiazides and other diuretics.
corticosteroids.
estrogens.
Do not chew, crush or break it. Axiglim M 1mg Tablet
Store below 30°C
If you miss a dose of Axiglim M 1mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
You have been prescribed this combination medicine as it can control blood sugar better than metformin alone.
You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with Axiglim M 1mg Tablet.
Take it with food to lower your chance of having an upset stomach.
Monitor your blood sugar level regularly while you are taking this medicine.
It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic.
Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as Axiglim M 1mg Tablet may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.
Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Axiglim M 1mg Tablet is to be taken with food.
Q. What are the recommended storage conditions for Axiglim M 1mg Tablet?
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Q. Can the use of Axiglim M 1mg Tablet lead to lactic acidosis?
Yes, the use of Axiglim M 1mg Tablet can lead to lactic acidosis. It is a medical emergency which is caused by increased levels of lactic acid in the blood. It is also known as MALA (Metformin-associated lactic acidosis). It is a rare side effect associated with the use of metformin and therefore, it is considered to be harmful for patients with underlying kidney disease, old age patients or who take large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, feeling of cold in arms and legs, difficulty in breathing, nausea, vomiting, stomach pain or slow heart rate. If you have these symptoms, stop taking Axiglim M 1mg Tablet and consult your doctor immediately.
Q. What is Axiglim M 1mg Tablet?
Axiglim M 1mg Tablet is a combination of two medicines: Glimepiride and Metformin. This medicine is used in the treatment of type 2 diabetes mellitus (DM). It improves blood glucose levels in adults when taken along with proper diet and regular exercise. Glimepiride lowers the blood glucose levels by increasing the release of insulin from the pancreas. Metformin works by lowering the glucose production in the liver and improving insulin sensitivity. This combination is not indicated for the treatment of type 1 DM.
Q. What are the possible side effects of Axiglim M 1mg Tablet?
The use of Axiglim M 1mg Tablet is associated with common side effects like hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, headache and upper respiratory tract infection. Its use can also lead to serious but rare side effects like lactic acidosis. On long-term use it can also lead to Vitamin B12 deficiency.
