Manufacturer: BMS India Pvt Ltd
Salt Composition : Aztreonam(1gm)
Azactum 1gm Injection is given as a drip (intravenous infusion) or as an injection directly into a vein or a muscle under the supervision of a healthcare professional. It should be used regularly at evenly spaced time intervals as prescribed by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping the medicine too early may lead to the infection returning or worsening. Inform your doctor if you have any previous history of allergy or heart problems before taking this medicine. Pregnant or breastfeeding women should consult their doctor before using this medicine.
The bactericidal action of aztreonam results from the inhibition of bacterial cell wall synthesis due to a high affinity of aztreonam for penicillin binding protein 3 (PBP3). By binding to PBP3, aztreonam inhibits the third and last stage of bacterial cell wall synthesis.
Aztreonam (AZM) is a monobactam antibiotic with a high level of activity against gram-negative micro-organisms, including Pseudomonas aeruginosa. We evaluated AZM pharmacokinetics and pharmacokinetic-pharmacodynamic relationships in patients with cystic fibrosis (CF) and healthy subjects.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Azactum
Rash
Injection site reactions (pain, swelling, redness)
Vomiting
Nausea
Diarrhea
diarrhea from an infection with Clostridium difficile bacteria.
liver problems.
decreased kidney function.
Azactum 1gm Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Consuming alcohol with Azactum 1gm Injection does not cause any harmful side effects.
Azactum 1gm Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Aztreonam injection is used to treat certain infections that are caused by bacteria, including respiratory tract (including pneumonia and bronchitis), urinary tract, blood, skin, gynecological, and abdominal (stomach area) infections, that are caused by bacteria.
bazedoxifene/conjugated estrogens.
cefoxitin.
conjugated estrogens.
dienogest/estradiol valerate.
digoxin.
estradiol.
estrogens conjugated synthetic.
estropipate.
Kindly do not self administer.
Store below 30°C
You have been prescribed Azactum 1gm Injection for the treatment of bacterial infections.
It is given by an injection or drip into a vein or into a muscle in the buttock or thigh.
Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools.
Inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking this medicine.
Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. Is Azactum 1gm Injection safe to use in patients who are allergic to penicillins?
Azactum 1gm Injection can be safely used in patients who are allergic to penicillins. This medicine has shown no cross-reactivity when used in patients with penicillin allergy.
