Azactum 2gm (Injection)

Manufacturer: BMS India Pvt Ltd

Salt Composition : Aztreonam(2gm)

Prescription
Prescription Required: Consult the Doctor & Get Your ePrescription

Azactum 2gm Injection is given as a drip (intravenous infusion) or as an injection directly into a vein or a muscle under the supervision of a healthcare professional. It should be used regularly at evenly spaced time intervals as prescribed by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping the medicine too early may lead to the infection returning or worsening.


Basic Information

Mechanism Of Action

The bactericidal action of aztreonam results from the inhibition of bacterial cell wall synthesis due to a high affinity of aztreonam for penicillin binding protein 3 (PBP3). By binding to PBP3, aztreonam inhibits the third and last stage of bacterial cell wall synthesis.


Pharmacokinets

Aztreonam (AZM) is a monobactam antibiotic with a high level of activity against gram-negative micro-organisms, including Pseudomonas aeruginosa. We evaluated AZM pharmacokinetics and pharmacokinetic-pharmacodynamic relationships in patients with cystic fibrosis (CF) and healthy subjects.


Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Azactum

Rash

Injection site reactions (pain, swelling, redness)

Vomiting

Nausea

Diarrhea


Contra Indications

diarrhea from an infection with Clostridium difficile bacteria.

liver problems.

decreased kidney function.


Pregnancy Related Information

Azactum 2gm Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.


Product And Alcohol Interaction

Consuming alcohol with Azactum 2gm Injection does not cause any harmful side effects.


Breast Feeding Related Information

Azactum 2gm Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.


Indications

Aztreonam injection is used to treat certain infections that are caused by bacteria, including respiratory tract (including pneumonia and bronchitis), urinary tract, blood, skin, gynecological, and abdominal (stomach area) infections, that are caused by bacteria.

Interactions

bazedoxifene/conjugated estrogens.

cefoxitin.

conjugated estrogens.

dienogest/estradiol valerate.

digoxin.

estradiol.

estrogens conjugated synthetic.

estropipate.

Typical Dosage

Kindly do not self administer.


Storage Requirements

Store below 30°C


Expert Advice

You have been prescribed Azactum 2gm Injection for the treatment of bacterial infections.

It is given by an injection or drip into a vein or into a muscle in the buttock or thigh.

Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.

Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools.

Inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking this medicine.

Inform your doctor if you are pregnant, planning to conceive or breastfeeding.


How To Use

Your doctor or nurse will give you this medicine. Kindly do not self administer.


FAQs

Q. Is Azactum 2gm Injection safe to use in patients who are allergic to penicillins?

Azactum 2gm Injection can be safely used in patients who are allergic to penicillins. This medicine has shown no cross-reactivity when used in patients with penicillin allergy.