Azopt Opthalmic Suspension (5ml)

Manufacturer: Alcon Laboratories

Salt Composition : Brinzolamide(1% w/v)


Never use Azopt Opthalmic Suspension if the seal is broken before you use it for the first time. Wash your hands before using it and shake the bottle well before each use. If you wear contact lenses, make sure you remove them before instilling them and wait for at least 15 minutes before putting them back. Do not stop using this medicine without asking your doctor. Otherwise, the pressure in your eye will not be controlled and this could damage your sight.The most common side effects are blurred vision and a bitter taste in your mouth. Sometimes people experience more general effects such as shortness of breath, dizziness, tiredness, or heart palpitations. If your vision is blurred or you have other changes in sight for a time, do not drive until your vision is clear.


Basic Information

Mechanism Of Action

Inhibition of carbonic anhydrase in the ciliary processes of the eye decreases aqueous humor secretion, presumably by slowing the formation of bicarbonate ions with subsequent reduction in sodium and fluid transport. The result is a reduction in intraocular pressure (IOP).

Pharmacokinets

Brinzolamide is a topical carbonic anhydrase inhibitor which reduces the production of aqueous humor in the ciliary body, thereby reducing intra-ocular pressure. It is formulated as an ophthalmic suspension. The pharmacokinetics of ocular suspensions is not well understood.

Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Azopt

Blurred vision

Bitter taste

Contra Indications

Sulfonamide hypersensitivity. Brinzolamide is contraindicated in patients with hypersensitivity to any component of the product.

Renal disease, renal impairment.

Hepatic disease.

Closed-angle glaucoma.

Pregnancy.

Breast-feeding.

Children.

Contact lenses.

Pregnancy Related Information

Azopt Opthalmic Suspension may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.


Product And Alcohol Interaction

No interaction found/established


Breast Feeding Related Information

Azopt Opthalmic Suspension is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.


Children Related Information

Use with caution

Below 9years: Contraindicated

Indications

Brinzolamide is indicated in the treatment of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma.

Interactions

acetazolamide

aspirin

bismuth subsalicylate

choline salicylate

dichlorphenamide

diflunisal

magnesium salicylate

methazolamide

salsalate

sodium salicylate

sodium thiosalicylate

topiramate

zonisamide

Typical Dosage

Check the label for directions before use. Hold the dropper close to the eye without touching it. Gently squeeze the dropper and place the medicine inside the lower eyelid. Wipe off the extra liquid.

Storage Requirements

Store below 25°C

Effects Of Missed Dosage

If you miss a dose of Azopt Opthalmic Suspension, use it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.


Effects Of Overdose

Consult a doctor before taking any medicines.

Expert Advice

Azopt Opthalmic Suspension helps lower high pressure in the eye and reduce the risk of vision loss.

For best results, put one drop 2-3 times daily in the affected eye(s).

Apply pressure on the corner of the eye (close to the nose) for about 1 minute, immediately after instilling the drop. This minimizes the risk of side effects.

Do not touch the tip of the dropper to any surface, or to your eye, to avoid contaminating the eye drops.

Remove contact lenses before using Azopt Opthalmic Suspension, and wait at least 15 minutes before re-inserting them.

When applying multiple eye medications, wait for at least 5-15 minutes before delivering the next medication in the same eye to avoid dilution of the medicine.

How To Use

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Hold the dropper close to the eye without touching it. Gently squeeze the dropper and place the medicine inside the lower eyelid. Wipe off the extra liquid.


FAQs

Q. What is the right way to use Azopt Opthalmic Suspension?

Always wash your hands before (and after) using Azopt Opthalmic Suspension. This prevents you from passing the infection from one eye to the other. Remove the cap just before using your medicine and replace it as soon as you have finished. Avoid touching the nozzle of the bottle with your fingers. Tilt your head back and gently pull down your lower eyelid with a clean finger. Hold the bottle over the eye and allow a single drop to fall into the space between your lower lid and your eye. Close your eye and gently press your finger over the inside corner of your eye (over the eyelid) for about a minute. This helps prevent the drop from draining out of the eye. Repeat in your other eye if your doctor has told you to do this.

Q. How many times should I use Azopt Opthalmic Suspension in a day?

Ideally, you should use the drops regularly, three times a day, or as prescribed by your doctor.

Q. Does Azopt Opthalmic Suspension cause blurred vision?

When you instill the eye drops for the first time, it can make your eyes watery and may sometimes cause blurred vision. If this happens, it will quickly clear. Make sure you can see clearly again before you drive, or use tools or machines.

Q. I am experiencing headaches after the start of the treatment with Azopt Opthalmic Suspension. Is this normal?

Although rare, headache is one of the side-effects of Azopt Opthalmic Suspension. You may ask your doctor to recommend a suitable painkiller. If the headache continues, speak with your doctor.

Q. When should I seek a doctor’s advice?

You should contact your doctor immediately if you develop swelling in the eyelids, eye pain, dry eye(s), foreign body sensation in the eyes, headache, and discharge from the eyes. Also, inform your doctor if you had or have any scheduled eye surgery.

Q. Can I use Azopt Opthalmic Suspension if I wear contact lenses?

If you usually wear contact lenses, do not wear them while you're using Azopt Opthalmic Suspension. You can re-insert the lens 15 minutes after using Azopt Opthalmic Suspension. Contact your doctor if there is any eye irritation that persists.

Q. Can I use any other eye drop along with Azopt Opthalmic Suspension?

Always consult your doctor before using any other eye drops along with Azopt Opthalmic Suspension. It is advisable to give a gap of atleast 10-15 minutes between the two medications.

Q. In which conditions the use of Azopt Opthalmic Suspension should be avoided?

Use of Azopt Opthalmic Suspension should be avoided in patients who are allergic to it or any of its components. However, if you are not aware of any allergy or if you are using this medicine for the first time, consult your doctor.