Manufacturer: Abbott
Salt Composition : Sulfamethoxazole(400mg), Trimethoprim(80mg)
Bactrim DS Tablet is a combination medicine that is used to treat various types of bacterial infections such as pneumonia, bronchitis, infections of the urinary tract, ear, and abdomen. It prevents the growth of microorganisms to cure the infection.
Bactrim DS Tablet is a prescription medicine that is advised to be taken as suggested by the doctor. It should be taken with food and it must be taken at a fixed time to ensure better efficacy. Do not consume more than the recommended dose, as an overdose of it may have harmful effects on your body. If you miss a dose, take it as soon as you remember. The treatment must be completed even if you feel better to ensure a complete recovery.
Bactrim DS Tablet may lead to some side effects such as nausea, vomiting, stomach pain, loss of appetite, headache, etc. To overcome any such side effects, it is advised to eat a healthy balanced diet and drink plenty of fluid. If any of the side effects get aggravated, contact your doctor immediately. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must consult your doctor immediately.
Before taking this medicine, you should tell your doctor if you have any problems with your liver or kidneys. Also, tell your doctor if you are on any medication for any health condition. Pregnant or breastfeeding women should also consult with the doctor before taking it. Avoid drinking alcohol as it can cause excessive dizziness with this medicine. It usually does not impair your ability to drive, but you should not drive if it makes you feel sleepy or dizzy. If you are a known allergic to the medicine, you must refrain from using this medicine and consult your doctor. It is advised to take proper rest during the course of treatment for the medicine to work effectively.
Sulfamethoxazole inhibits the synthesis of dihydrofolic acid. Trimethoprim inhibits thymidine and DNA synthesis. These two agents act synergistically in inhibiting folic acid synthesis
The pharmacokinetics of trimethoprim and sulfamethoxazole were compared in eight critically ill versus nine non-critically ill male patients and were as follows, respectively: clearance, 1.88 +/- 0.44 versus 1.73 +/- 0.64 ml/min/kg for trimethoprim and 0.40 +/- 0.12 versus 0.34 +/- 0.11 ml/min/kg for sulfamethoxazole
Nausea
Vomiting
Skin rash
Allergic reaction
Use during early pregnancy has been related to congenital malformations and maternal folic acid deficiency; this may cause neural tube defects (spina bifida), urinary tract defects, oral clefts, and clubbed feet.
Bactrim DS Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
It is not known whether it is safe to consume alcohol with Bactrim DS Tablet. Please consult your doctor.
Bactrim DS Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
There may be a possibility of skin rash in the baby.
The FDA-Approved indications include acute infective exacerbation of chronic bronchitis, otitis media in pediatrics only, travelers diarrhea for treatment and prophylaxis, urinary tract infections, shigellosis, pneumocystis jirovecii, pneumonia/pneumocystis carinii pneumonia (PJP/PCP), and toxoplasmosis
colitis.
hematologic toxicity.
hypersensitivity reactions.
liver disease.
porphyria.
renal dysfunction.
folate deficiency.
crystalluria.
Do not chew, crush or break it. Bactrim DS Tablet is to be taken with food.
If you miss a dose of Bactrim DS Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines
You have been prescribed Bactrim DS Tablet for the treatment of many types of bacterial infections.
Finish the prescribed course of Bactrim DS Tablet, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it does not stop or if you find blood in your stools.
Stop taking Bactrim DS Tablet and inform your doctor if you develop skin rash/blisters or other unexplained skin reaction while taking Bactrim DS Tablet.
In case of long-term use, have regular monthly blood tests to monitor your blood cells as suggested by your doctor.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Bactrim DS Tablet is to be taken with food.
Q. What is Bactrim DS Tablet?
Bactrim DS Tablet is a combination of two medicines: Sulfamethoxazole+Trimethoprim. It is an antibiotic used to treat certain bacterial infections and works by stopping the growth of the bacteria causing the infection. It treats urinary tract infections, ear infections, enteritis (inflammation of the small intestine), pneumonia, traveler's diarrhea, and episodes of difficulty breathing in people with chronic (long-term) bronchitis.
Q. Is it safe to use Bactrim DS Tablet?
Yes, Bactrim DS Tablet is safe to use in most patients. However, in some patients, it may cause some unwanted common side effects like Nausea, Vomiting, Skin rash, Allergic reaction. Inform your doctor as soon as possible if you experience any persistent problem while taking this medication.
Q. Can the use of Bactrim DS Tablet cause nausea and vomiting?
Yes, the use of Bactrim DS Tablet can cause nausea and vomiting. In case, you experience nausea while taking this medicine, take it with milk, food or with antacids. Avoid taking fatty or fried foods. If you start to experience vomiting, drink plenty of water or other fluids. Try small frequent sips of the liquid. Talk to your doctor if you have persistent vomiting and signs of dehydration like dark colored and strong-smelling urine and a low frequency of urination. Do not take any other medicines without speaking to a doctor.
Q. Are there any specific contraindications associated with the use of Bactrim DS Tablet?
Bactrim DS Tablet is contraindicated in patients with known allergy to any of the component or excipients of this medicine and in patients with a history of drug-induced immune thrombocytopenia (low platelet count), megaloblastic anemia due to folate deficiency. The medicine is also contraindicated in pediatric patients less than 2 months of age and in patients with marked hepatic damage or with severe renal insufficiency when renal function status cannot be monitored.
