Benzylpenicillin 500000IU (Injection)

Prescription
Prescription Required: Consult the Doctor & Get Your ePrescription

Benzylpenicillin 500000IU Injection is also used to prevent some infections such as Rheumatic fever and infection of the heart valves (bacterial endocarditis) in people with pre-existing heart disease. It is a penicillin-type of antibiotic, which mainly fights and stops the growth of the gram-positive type of bacteria. It is given as a drip (intravenous infusion) or as an injection directly into a vein or a muscle under the supervision of a healthcare professional. This medicine should be used regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping the medicine too early may lead to the infection returning or worsening. The total duration of treatment and precise dosage will be decided by your doctor, depending on the type of infection that you have and how well you respond to the medication.

Before taking this medicine, inform your doctor if you are allergic to penicillin or any penicillin-type of medicine. Rash, allergic reactions or pain, swelling, and redness at the site of injection may be seen as side effects in some patients. These are temporary and usually resolve quickly. Consult your doctor if any of these side effects persist or if your condition worsens. This medicine is generally regarded as safe to use during pregnancy if used under a doctor’s supervision.


Basic Information

Mechanism Of Action

Penicillin G exerts a bactericidal action against penicillin-susceptible microorganisms during the stage of active multiplication. It acts through the inhibition of biosynthesis of cell-wall peptidoglycan, rendering the cell wall osmotically unstable.


Pharmacokinets

The pharmacokinetic advantage to this drug is that high serum concentrations are achieved rapidly, but the half-life is approximately 30 minutes, necessitating redoing every 4-6 hours. Penicillin G is poorly absorbed orally, with a bioavailability of 15-30%.


Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Benzylpenicillin

Rash

Allergic reaction

Injection site reactions (pain, swelling, redness)


Contra Indications

Contraindications of penicillin include a previous history of severe allergic reactions or penicillin and its derivatives. Penicillin is also contraindicated in patients who have had Stevens-Johnson syndrome after administering penicillin or a penicillin derivative.

Pregnancy Related Information

Benzylpenicillin 500000IU Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.


Product And Alcohol Interaction

Consuming alcohol with Benzylpenicillin 500000IU Injection does not cause any harmful side effects.


Breast Feeding Related Information

Benzylpenicillin 500000IU Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.


Indications

Pneumonia. Indicated for moderately severe uncomplicated pneumococcal pneumonia. ...

Streptococcal Infections (Group A) ...

Staphylococcal Infections. ...

Bacterial Endocarditis. ...

Syphilis. ...

Anthrax. ...

Diphtheria. ...

Vincent's Infection (fusospirochetosis)


Interactions

colitis.

renal dysfunction.

hyperkalemia.

asthma/allergies.

hemodialysis.


Typical Dosage

Kindly do not self administer.


Storage Requirements

Store below 30°C


Effects Of Missed Dosage

If you miss a dose of Benzylpenicillin 500000IU Injection, consult your doctor.


Effects Of Overdose

Consult a doctor before taking any medicines.


Expert Advice

You have been prescribed Benzylpenicillin 500000IU Injection for the treatment of bacterial infections.

It is given by an injection into a vein or muscle, or via a drip into a vein.

Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.

Inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking this medicine.


How To Use

Your doctor or nurse will give you this medicine. Kindly do not self administer.


FAQs

Q. What should I discuss with my doctor before receiving Benzylpenicillin 500000IU Injection?

Before taking Benzylpenicillin 500000IU Injection, you should tell your doctor if you have ever had an allergic reaction to Benzylpenicillin 500000IU Injection or any similar medicine. Inform the doctor if you have any type of allergy, asthma or breathing problems, heart disease or kidney disease. Let your doctor know about all the medicines that you may be taking as they may affect or be affected by Benzylpenicillin 500000IU Injection. Pregnant or breastfeeding mothers should also seek their doctor’s advice before taking Benzylpenicillin 500000IU Injection.

Q. Why does Benzylpenicillin 500000IU Injection shot hurt so much?

Benzylpenicillin 500000IU Injection is injected deeply into the muscle, usually into the butt muscle, using a lot of fluid used to inject it. Moreover, it is injected slowly which makes it even more painful.

Q. How is Benzylpenicillin 500000IU Injection given?

Benzylpenicillin 500000IU Injection must be injected slowly and deeply into a muscle of the buttock or hip. Do not inject this medicine near or into an artery, vein, or nerve as it could lead to some serious side effects.

Q. The solution looks discolored. Can I still use Benzylpenicillin 500000IU Injection?

No. You should not use Benzylpenicillin 500000IU Injection if the medicine has changed colors or has particles in it. The discolored solution may be contaminated and may not be as effective as it is expected to be. Also, it may cause additional side effects. So, it is better, that you discard the solution and go for another vial.