Manufacturer: Avinash Health Products Pvt Ltd
Salt Composition : Glimepiride(1mg), Metformin(500mg), Pioglitazone(15mg)
Strip of 10 Tablet
(Inclusive of all taxes)
Some people may develop hypoglycemia (low blood sugar level) when this medicine is taken along with other antidiabetic medicines, alcohol or upon skipping a meal. Monitor your blood sugar levels regularly while taking it. Other common side effects of this medicine include nausea, taste changes, diarrhea, stomach pain, headache, edema (swelling), blurred vision, bone fracture, and respiratory tract infection.
The BEPRIDE 2MG TABLET contains Glimepiride which acts on insulin-secreting cells called beta cells inside the pancreas, activates calcium channels on cells which lets insulin pass out of the cell. This insulin then makes each cell in the body take up glucose and utilize it, thus lowering raised blood glucose.
Pharmacokinetics. Gastrointestinal absorption is complete, with no interference from meals. Significant absorption can occur within one hour, and distribution is throughout the body, 99.5% bound to plasma protein. Metabolism is by oxidative biotransformation, it is hepatic and complete,Metformin has an oral bioavailability of 50–60% under fasting conditions, and is absorbed slowly. Peak plasma concentrations (Cmax) are reached within 1–3 hours of taking immediate-release metformin and 4–8 hours with extended-release formulations,Pioglitazone is a thiazolidinedione that increases insulin sensitivity in target tissues. It is well-absorbed, with a mean absolute bioavailability of 83% and reaching maximum concentrations in around 1.5 hours. It is metabolised by the hepatic cytochrome P450 enzyme system.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Bepride Plus
Hypoglycemia (low blood glucose level)
Nausea
Taste change
Diarrhea
Stomach pain
Headache
Edema (swelling)
Weight gain
Blurred vision
Bone fracture
Respiratory tract infection
Drug-Disease Interaction: If you have bladder cancer, uncontrolled diabetes, lactic acidosis, diabetic ketoacidosis (accumulation of ketone bodies in the blood), eye problems caused by diabetes, liver, kidney or heart problems, inform your doctor before taking Bepride Plus 1mg/500mg/15mg Tablet
Bepride Plus 1mg/500mg/15mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is unsafe to consume alcohol with Bepride Plus 1mg/500mg/15mg Tablet.
Use with caution
Bepride Plus 1mg/500mg/15mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Monitor the breastfed baby’s blood sugar during treatment with Bepride Plus 1mg/500mg/15mg Tablet
Bepride Plus 1mg/500mg/15mg Tablet contains three antidiabetic drugs Bepride Plus 1mg/500mg/15mg Tablet used in the treatment of type 2 diabetes. Glimepiride stimulates cells in the pancreas that produce insulin which helps to remove sugar from the blood.
You are not recommended to take Bepride Plus 1mg/500mg/15mg Tablet with pregabalin as it may cause weight gain and fluid retention that could lead to heart failure. However, please consult a doctor before using Bepride Plus 1mg/500mg/15mg Tablet with other medicines.
Do not chew, crush or break it. Bepride Plus 1mg/500mg/15mg Tablet is to be taken with food.
Store below 30°C
If you miss a dose of Bepride Plus 1mg/500mg/15mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Take it with food to lower your chance of having an upset stomach.
It may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms such as cold sweats, cool pale skin, tremor, and anxiety.
Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Bepride Plus 1mg/500mg/15mg Tablet is to be taken with food.
Q. Can I drink alcohol while taking Bepride Plus 1mg/500mg/15mg Tablet?
No, it is not safe to drink alcohol while using Bepride Plus 1mg/500mg/15mg Tablet. Drinking alcohol may lower your blood sugar levels (hypoglycemia). Also, it can increase the chances of lactic acidosis.
Q. What should I inform the doctor before taking Bepride Plus 1mg/500mg/15mg Tablet?
Before taking Bepride Plus 1mg/500mg/15mg Tablet inform your doctor if you have congestive heart failure, kidney problems, liver problems, swelling of the back of the eye. Inform the doctor if you are pregnant, breastfeeding or a premenopausal woman. Let the doctor know if you are taking any prescription and non-prescription medicines, vitamins, and herbal supplements.
Q. Can the use of Bepride Plus 1mg/500mg/15mg Tablet lead to Vitamin B12 deficiency?
Yes, the use of Bepride Plus 1mg/500mg/15mg Tablet can cause vitamin B12 deficiency as it contains metformin in it. On long-term use, it interferes with absorption of vitamin B12 in the stomach.
Q. Can the use of Bepride Plus 1mg/500mg/15mg Tablet cause hypoglycemia?
Yes, the use of Bepride Plus 1mg/500mg/15mg Tablet can cause hypoglycemia (low blood sugar level). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate and feeling anxious or shaky. It happens more often if you miss or delay your meal, drink alcohol, over-exercise or take other antidiabetic medicine along with it. So, regular monitoring of blood sugar level is important. Always carry some sugary item like a candy or chocolate with you.
Q. What are the instructions for the storage and disposal of Bepride Plus 1mg/500mg/15mg Tablet?
Keep this medicine in the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
