Bevatas 100mg Injection

Manufacturer: Intas Pharmaceuticals Ltd

Salt Composition : Bevacizumab(100mg)


Bevatas 100 Injection is an effective medicine, first-line option when used together with other cancer medicines. It is given as an infusion. That means you get it through a small needle in your vein or through a port, which is a device placed under your skin. The doctor will decide your dose and duration and will check you for signs of an infusion reaction such as high blood pressure and trouble breathing. You keep taking Bevatas 100 Injection as long as your disease is controlled and your side effects are manageable. Your doctor will determine whether you should stop taking it or not. You may be advised to check blood pressure and levels of protein in urine while you are taking this medication.



Basic Information

Mechanism Of Action

Bevatas 100 Injection is a anti-angiogenic medication. It works by blocking a protein called vascular endothelial growth factor (VEGF). This stops the formation of blood vessels that bring oxygen and nutrients to cancerous cells.

Pharmacokinets

Bevacizumab acts by selectively binding circulating VEGF, thereby inhibiting the binding of VEGF to its cell surface receptors. This inhibition leads to a reduction in microvascular growth of tumor blood vessels and thus limits the blood supply to tumor tissues.

Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Bevatas

Rectal bleeding

Taste change

Headache

Nosebleeds

Back pain

Dry skin

High blood pressure

Protein in urine

Inflammation of the nose

Contra Indications

Hypersensitivity to Bevatas 100 Injection is a contraindication. In addition, Bevatas 100 Injection should not be used if you have the following conditions:

Gastrointestinal perforation

Hypertensive crisis

Recent history of coughing blood

Within 28 days of major surgery

Pregnancy Related Information

Bevatas 100 Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.


Product And Alcohol Interaction

It is not known whether it is safe to consume alcohol with Bevatas 100 Injection. Please consult your doctor.


Breast Feeding Related Information

Bevatas 100 Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.


Children Related Information

Use with caution Below 5years: Contraindicated

Indications

Bevacizumab, in combination with erlotinib, is indicated for first-line treatment of adult patients with unresectable advanced, metastatic or recurrent non-squamous non-small cell lung cancer with Epidermal Growth Factor Receptor (EGFR) activating mutations.

Interactions

fistula formation.

GI perforation.

bleeding.

hypertension.

PRES.

proteinuria.

thromboembolic disorders.

Typical Dosage

Kindly do not self-administer.

Storage Requirements

Store in a refrigerator (2 - 8°C). Do not freeze.


Effects Of Missed Dosage

If you miss a dose of Bevatas 100 Injection, please consult your doctor.


Effects Of Overdose

Consult a doctor before taking any medicines.

Expert Advice

Bevatas 100 Injection is an effective, first-line option when used together with other medicines for certain types of cancers such as colorectal, lung, cervical, and kidney cancers.

Bevatas 100 Injection is given as an infusion. Your doctor or nurse will monitor you for signs of an infusion reaction such as high blood pressure and trouble breathing.

It can lower your wound healing ability. Inform your doctor that you are taking this medication before undergoing any surgical procedure.

It can increase the risk of bleeding. Inform your doctor if you notice any unusual bleeding or bleeding that doesn't stop easily.

Your doctor may regularly check your blood pressure and levels of protein in your urine while you are on Bevatas 100 Injection.

How To Use

Your doctor or nurse will give you this medicine. Kindly do not self-administer.


FAQs

Q. What kinds of cancer can Bevatas 100 Injection be used for ?

Bevatas 100 Injection is approved for the treatment of cancer of the colon or rectum that has spread to other parts of the body. It must be given along with chemotherapy. Other types of cancers that it helps with includes certain types of lung cancer, kidney cancer, ovarian cancer, cervical cancer, and glioblastoma (a type of brain tumor).

Q. How is Bevatas 100 Injection given?

Bevatas 100 Injection is given as an infusion. That means you get it through a small needle in your vein or through a port, which is a device placed under your skin. Your doctor will decide your dose and duration and will monitor you for signs of an infusion reaction.

Q. How long can I take Bevatas 100 Injection for?

You keep taking Bevatas 100 Injection as long as your disease is controlled and your side effects are manageable. Your doctor will determine whether you should stop taking Bevatas 100 Injection. If your cancer progresses during this initial treatment, talk to your doctor if a different chemotherapy may be an option.

Q. How Bevatas 100 Injection works differently from chemotherapy?

Chemotherapy attacks fast-growing cells, like cancer cells. In contrast, the purpose of Bevatas 100 Injection is to prevent the growth of new blood vessels that feed tumors. This causes the tumour to shrink, or to stop growing.

Q. Does a person taking Bevatas 100 Injection still need chemotherapy?

Chemotherapy is still needed along with taking Bevatas 100 Injection. It makes chemotherapy work better.