Bharglob 16.5% Injection (2ml)


Bharglob 16.5% Injection has been shown to be effective in preventing infections in bone marrow transplant patients more than 20 years of age in the first 100 days post-transplant. It is used in the treatment of patients where antibody-forming capacity is severely impaired thereby subjecting them to a greater risk of infections. Bharglob 16.5% Injection gives you antibodies that your body is not making on its own so you can fight infections. Both children and adults can have this therapy. It is administered as an injection. Your doctor will monitor you for some time after the administration of Bharglob 16.5% Injection to check for any side effects.



Basic Information

Mechanism Of Action

Bharglob 16.5% Injection strengthens or boost the immune system and lower the risk of infection in persons with a weakened immune system. It works by producing antibodies against foreign substances thereby fighting against infection.

Pharmacokinets

The mechanisms of action of Ig not only involve the blockade of Fc receptors of phagocytes, but also control complement pathways, idiotype-anti-idiotype dimer formation, blockage of superantigen binding to T cells, inhibition of dendritic cells and stimulation of regulatory T cells (Tregs).

Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Bharglob

Back pain

Chills

Flushing (sense of warmth in the face, ears, neck and trunk)

Dizziness

Headache

Nausea

Decreased blood pressure

Muscle pain

Slow heart rate

Wheezing

Contra Indications

meningitis not due to an infection.

diabetes.

monoclonal gammopathy, a condition with abnormal proteins in the blood.

a type of blood disorder where the red blood cells burst called hemolytic anemia.

high blood pressure.

chronic heart failure.

hardening of the arteries due to plaque buildup.

Pregnancy Related Information

Bharglob 16.5% Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.


Product And Alcohol Interaction

It is not known whether it is safe to consume alcohol with Bharglob 16.5% Injection. Please consult your doctor.


Breast Feeding Related Information

Bharglob 16.5% Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.


Children Related Information

Use with caution Below 9years: Contraindicated

Indications

Human Normal Immunoglobulin is used for the treatment of certain diseases that are caused due to lack of antibodies in your blood. It may be injected under the skin or given into a muscle. Your doctor will monitor you for some time after administration of Human Normal Immunoglobulin to check for any side effects.

Interactions

HUMAN NORMAL IMMUNOGLOBULIN may interact with loop diuretics (furosemide and ethacrynic acid) and live vaccines (MMR vaccine (measles, mumps, and rubella) and varicella vaccine).

Typical Dosage

Kindly do not self administer.

Storage Requirements

Store in a refrigerator (2 - 8°C). Do not freeze.


Effects Of Missed Dosage

If you miss a dose of Bharglob 16.5% Injection, please consult your doctor.


Effects Of Overdose

Consult a doctor before taking any medicines.

Expert Advice

Bharglob 16.5% Injection is used for the treatment of certain diseases that are caused due to lack of antibodies in your blood.

It may be injected under the skin or given into a muscle.

Your doctor will monitor you for some time after administration of Bharglob 16.5% Injection to check for any side effects.

Do not drive or do anything requiring concentration unless you know how Bharglob 16.5% Injection affects you.

Inform your doctor if you have received any live vaccine (e.g. oral polio, MMR) in the last three months.

How To Use

Your doctor or nurse will give you this medicine. Kindly do not self administer.


FAQs

Q. What should I keep in mind while taking Bharglob 16.5% Injection?

Bharglob 16.5% Injection can reduce the efficiency of some vaccines (like measles/mumps/rubella or chickenpox vaccines). So, inform your doctor that you are on Bharglob 16.5% Injection before you get any vaccines. Also, let your doctor know if you are pregnant, planning to get pregnant or if you are breastfeeding.

Q. If I feel fine, does it mean that I can discontinue my treatment with Bharglob 16.5% Injection?

No, this only means that you are responding well to the treatment. Do not stop taking this medicine without consulting the doctor. If you stop the medication before completing the treatment then you would be putting yourself at risk as your body would no longer be able to fight infections. However, in case of doubt, you should always talk to your doctor.

Q. How long will it take for Bharglob 16.5% Injection to start working?

Your symptoms may take 3-4 weeks to improve. This duration can vary depending on the disease you have and the way you respond to the treatment. If you are not sure, consult your doctor.

Q. Can Bharglob 16.5% Injection cause kidney damage?

Yes, Bharglob 16.5% Injection can cause kidney damage but not in everyone. Patients having a pre-existing kidney problem, diabetes and hypovolemia (a decrease in the volume of circulating blood) are at risk of developing kidney failure. Additionally, patients who are overweight, over 65 years of age and who are using medicines that can cause kidney damage are also at risk of developing kidney failure. Also, Bharglob 16.5% Injection which has sucrose, fructose or maltose as an ingredient in it is more likely to cause kidney damage.

Q. Does Bharglob 16.5% Injection cause hair loss?

No, Bharglob 16.5% Injection does not cause hair loss. If you experience hair loss, it might be due to some other underlying problem. Please consult your doctor if it bothers you.