Manufacturer: BestoChem Formulations India Ltd
Salt Composition : Ceftriaxone(250mg), Sulbactam(125mg)
Vial of 1 Injection
(Inclusive of all taxes)
Big-Tum 375 Injection should only be administered under the supervision of a healthcare professional. Do not miss any scheduled appointments for taking this medicine. The course of the treatment must be completed even if you feel better. Sudden discontinuation of the treatment may affect the potency of the medicine.
Big-Tum 375 Injection contains two different medicines, Ceftriaxone and Sulbactum, that work together to kill the bacteria that cause infections. Ceftriaxone works by stopping the growth of bacteria. Sulbactam reduces resistance and enhances the activity of Ceftriaxone against bacteria.
Ceftriaxone can be administered intravenously and intramuscularly, and the drug is completely absorbed. It is not available orally. Distribution: Ceftriaxone penetrates tissues and body fluids well, including cerebrospinal fluid to treat central nervous system infections.Sulbactam, a new beta-lactamase inhibitor, has pharmacokinetic characteristics in humans similar to those of ampicillin and amoxicillin. Its half-life in humans is approximately 1 h.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Big-Tum
Diarrhea
Increased liver enzymes
Allergic reaction
Rash
Hypersensitivity to Big-Tum 375 Injection is a contraindication. In addition, Big-Tum 375 Injection should not be used if you have the following conditions:
Asthma
Clostridium difficile bacterial infection
Diabetes
Hyperbilirubinemic infants
Hypersensitivity
Hypersensitivity to cephalosporins
Kidney or gastrointestinal disease
Neonates requiring IV solutions that contain calcium
Pseudomembranous colitis
Runny nose due to allergy
Big-Tum 375 Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Consuming alcohol with Big-Tum 375 Injection does not cause any harmful side effects.
Big-Tum 375 Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Use with caution Below 9years: Contraindicated
Ceftriaxone & Sulbactam for Injection is indicated in infections caused by Ceftriaxone sodium- sensitive pathogens and may be used in the clinical settings in Sepsis, Meningitis, Abdominal Infections (e.g. Peritonitis, infection of the biliary tract), infections of the Bones, Joints, Soft tissue, Skin and of wounds.
If you use other drugs or over the counter products at the same time, the effects of Big-Tum 375 Injection may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. Big-Tum 375 Injection may interact with the following drugs and products:
Allopurinol
Calcium
Chloramphenicol
Probenecid
Tetracyclines
Kindly do not self administer.
Store below 30°C
If you miss a dose of Big-Tum 375 Injection, please consult your doctor.
Consult a doctor before taking any medicines.
You have been prescribed this combination medicine to treat bacterial infections even if they have developed resistance.
Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
Diarrhea may occur as a side effect. Taking probiotics along with Big-Tum 375 Injection may help. Talk to your doctor if you notice bloody stools or develop abdominal cramps.
Stop taking Big-Tum 375 Injection and inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking it.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. Can the use of Big-Tum 375 Injection cause allergic reaction?
Yes, Big-Tum 375 Injection can cause an allergic reaction and is considered to be harmful for patients with known allergy to a group of antibiotic called cephalosporins. Seek emergency medical help if you have any sign of an allergic reaction like hives; difficulty in breathing; swelling of your face, lips, tongue, or throat.
Q. Can the use of Big-Tum 375 Injection cause diarrhea?
Yes, the use of Big-Tum 375 Injection can cause diarrhea. It is an antibiotic which kills the harmful bacteria. However, it also affects the helpful bacteria in your stomach or intestine and causes diarrhea. If you are experiencing severe diarrhea, talk to your doctor about it.
Q. How long does Big-Tum 375 Injection takes to work?
Usually, Big-Tum 375 Injection starts working soon after taking it. However, it may take some days to kill all the harmful bacteria and make you feel better.
Q. What if I don't get better after using Big-Tum 375 Injection?
Inform your doctor if you don't feel better after finishing the full course of treatment. Also, inform him if your symptoms are getting worse while using this medicine.
Q. Can I stop taking Big-Tum 375 Injection when I feel better?
No, do not stop taking Big-Tum 375 Injection and complete the full course of treatment even if you feel better. Your symptoms may improve before the infection is completely cured.
