Manufacturer: BestoChem Formulations India Ltd
Salt Composition : Methylcobalamin(1000mcg), Niacinamide(100mg), Vitamin B6(Pyridoxine)(100mg)
Vial of 2ml Injection
(Inclusive of all taxes)
Bigvin Plus Injection is administered under the supervision of a healthcare professional. Do not self-administer this injection. Inform your doctor if you have any known allergies to this medication.
Bigvin Plus Injection is a combination of three nutritional supplements: Methylcobalamin, Niacinamide and Vitamin B6 (Pyridoxine), which replenishes the body's stores of important nutrients.
Methylcobalamin can be administered orally, parenterally and intranasal. Methylcobalamin binds with an intrinsic factor and form a complex which is absorbed in distal ileum. Its half life is 6 days.The pharmacokinetics of nicotinamide were studied in four human volunteers after oral doses of 1–6 g. Plasma concentrations and clearance rates of the vitamin were found to be dose-dependent, with a half-life of ∼7–9 h for the two highest doses administered (4 and 6 g), ∼4 h with 2 g and ∼1.5 h with a 1-g dose.There is no indication of circadian rhythm in vitamin B6-levels in blood plasma. Pharmacokinetics of vitamin B6 differ fundamentally, depending from the route of administration. The rate constants of elimination of B6-metabolites indicate a tendency of accumulation. Pyridoxine is rapidly metabolized in erythrocytes.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Bigvin Plus
No common side effects seen
If you are suffering from any of the following diseases, you should not take Methylcobalamin + Niacinamide + Vitamin B6 (Pyridoxine) unless your doctor advises you to do so -
Leber Congenital Amaurosis
Iron Deficiency Anemia
Kidney Disease
Polycythemia Vera
Peptic Ulcer
Low Blood Pressure
Liver Disease
Drug Allergy
Gout
Kidney Disease
High Uric Acid Levels in the Blood
Kidney Disease
Drug Allergy
Seizures
Information regarding the use of Bigvin Plus Injection during pregnancy is not available. Please consult your doctor.
Caution is advised when consuming alcohol with Bigvin Plus Injection. Please consult your doctor.
Bigvin Plus Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Use with caution
Below 9years: Contraindicated
General debility.
Diabetic disorders.
Cardiovascular Disease.
Pre & post operative condition.
Adjuvant therapy with antibiotics.
Improve blood components.
Muscular dystrophy.
Tongue infection.
If you use other drugs or over the counter products at the same time, the effects of Bigvin Plus Injection may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. Bigvin Plus Injection may interact with the following drugs and products:
Arsenic trioxide
Chloramphenicol
Cimetidine
Colchicine
Famotidine
Lansoprazole
Neomycin
Omeprazole
Ranitidine
Sodium Succinate
Kindly do not self administer.
Store below 30°C
If you miss a dose of Bigvin Plus Injection, please consult your doctor.
Consult a doctor before taking any medicines.
Bigvin Plus Injection helps treat vitamin B deficiency.
Inform your doctor if you are also taking medication for parkinson’s disease such as levodopa.
Inform your doctor if you are pregnant or breastfeeding.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. What is Bigvin Plus Injection?
Bigvin Plus Injection is a combination of three medicines: Nicotinamide, Cynacobalamin, and Folic acid. This medicine is used for treating or preventing vitamin deficiency. Deficiency of vitamins may cause anemia and other nerve problems.
Q. What is Vitamin deficiency anemia?
Vitamin deficiency anemia is a lack of healthy red blood cells caused when you have lower than normal amounts of certain vitamins. Vitamins whose deficiency leads to vitamin deficiency anemia include folic acid, vitamin B-12, and vitamin C. Vitamin deficiency anemia can also occur if your body has trouble absorbing or processing the vitamins. Vitamin deficiency anemia can usually be corrected with vitamin supplements and by making changes to your diet.
