Manufacturer: United Biotech Pvt Ltd
Salt Composition : Pamidronate(90mg)
Biodronate 90mg Injection is given by a doctor or nurse. You will not need to do this yourself. How much you are given, and how often, will be decided by your doctor. It may just be a single injection but if you are being treated for bone problems caused by the spread of cancer you may need regular injections. Your doctor will ask you to drink plenty of water before the injection, to avoid getting dehydrated. It may take several days to get the full benefit of this drug. Biodronate 90mg Injection is only part of a program of treatment that may also include changes to your diet and taking calcium and vitamin supplements.
Biodronate 90mg Injection is a bisphosphonate. It acts by suppressing the activity of osteoclasts, cells that cause the destruction of bone, thereby strengthening the bones and minimizing the risk of fractures.
Pamidronate is exclusively eliminated in the urine. By 120 hours after administration, 46±16% of the dose has been eliminated in the urine. The mean elimination half life of pamidronate is 28±7 hours. The mean total clearance of pamidronate is 107±50mL/min and the mean renal clearance is 49±28mL/min.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Biodronate
Headache
Back pain
Musculoskeletal (bone, muscle or joint) pain
Heartburn
Diarrhea
Indigestion
surgery on the thyroid gland.
low amount of magnesium in the blood.
low amount of phosphate in the blood.
low amount of calcium in the blood.
dehydration.
low amount of potassium in the blood.
inflammation of the tissues surrounding a tooth.
decreased kidney function.
Biodronate 90mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Consuming alcohol with Biodronate 90mg Injection does not cause any harmful side effects.
Biodronate 90mg Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
If you are taking Biodronate 90mg Injection during breastfeeding, monitor the baby's blood calcium levels during the first two months.
Use with caution
Below 9years: Contraindicated
Pamidronate is indicated to treat moderate to severe hypercalcemia of malignancy, moderate to severe Paget's disease of bone, osteolytic bone metastases of breast cancer, and osteolytic lesions of multiple myeloma.
If you use other drugs or over the counter products at the same time, the effects of Biodronate Injection may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. Biodronate Injection may interact with the following drugs and products:
Alendronate
Ibuprofen
Naproxen
Kindly do not self administer.
Store below 30°C
If you miss a dose of Biodronate 90mg Injection, skip it and continue with your normal schedule. Do not double the dose.
Consult a doctor before taking any medicines.
It is given by injection into a vein, usually over at least 15 minutes or as directed by your doctor.
Drink plenty of fluids to prevent dehydration and kidney damage.
It can lower the level of calcium in the blood. Take calcium and vitamin D supplements as suggested by your doctor.
You may develop fever or flu like symptoms, such as chills, tiredness and weakness. These are usually temporary and should go away after a few days. You may take a pain reliever/fever reducer to prevent or treat these symptoms.
It may cause a rare condition called osteonecrosis of the jaw. Have regular dental check-ups and inform your doctor if you develop sudden pain in your jaw.
Your doctor will monitor your response to Biodronate 90mg Injection by testing your bone mineral density (BMD). This is usually done every 1-3 years.
Do not take it if you are pregnant or breastfeeding.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. What does Biodronate 90mg Injection do?
Biodronate 90mg Injection helps in preventing breakdown of the bones. Bone is continuously being broken down and regenerated by special kinds of bone cells by a process called remodelling or turnover. However, conditions like bone stress and bone marrow edema may create pain and imbalance in this daily turnover. Biodronate 90mg Injection acts in the areas with increased bone turnover, decreases this process of breakdown and thereby reduces the pain and discomfort associated with it.
Q. How is Biodronate 90mg Injection administered?
Biodronate 90mg Injection should be administered under the supervision of a doctor or a trained healthcare professional and should not be self-administered. It is given as a 1-2 hour infusion by a drip into a vein in your arm. The dose will depend on the condition you are being treated for and will be decided by your doctor. Follow your doctor’s instructions carefully to get maximum benefit from Biodronate 90mg Injection.
Q. How often will I be given Biodronate 90mg Injection?
Your dose of Biodronate 90mg Injection will be decided by your doctor depending on your condition. Usually, an individual requires 1-3 doses of Biodronate 90mg Injection.However, the exact dose and its frequency will depend on your illness and how well you respond to the treatment.
Q. Is Biodronate 90mg Injection safe in pregnancy or breastfeeding?
No, Biodronate 90mg Injection may not be safe in pregnancy or breastfeeding. Although Biodronate 90mg Injection does not affect the fertility of women or the sperm count in males, it is best to consult your doctor before taking Biodronate 90mg Injection. In general, avoid Biodronate 90mg Injection if you are pregnant, planning to get pregnant or breastfeeding to avoid any harmful effects on the baby. There is not enough data available to know the exact effect of Biodronate 90mg Injection on the unborn baby or via breast milk. Also, women who are taking Biodronate 90mg Injection are advised to avoid pregnancy after 6 months of completing treatment with Biodronate 90mg Injection.. This is because traces of Biodronate 90mg Injection stays in the bones for long periods of time and may be released during this time which can cause harm to the baby.
Q. Does Biodronate 90mg Injection cause hair loss?
Yes, Biodronate 90mg Injection can cause hair loss, but this is not a common side effect. If you experience hair loss while taking this medication immediately report to your doctor and follow the advice given.
Q. Is Biodronate 90mg Injection safe?
Biodronate 90mg Injection is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.
Q. What other lifestyle changes should I make?
To get maximum benefit from Biodronate 90mg Injection, there are certain lifestyle changes that you must adhere to. Include some calcium or Vitamin D rich foods for bone strength. Try to spend more time in sunlight to get natural vitamin D. Quit smoking and reduce alcohol consumption as they may harm your bones. You can take up an exercise regime such as walking and low-impact aerobics as they are good for your bones. Similarly, you can try strength-training exercises where you use your own body weight which in turn improve bone health.
