Manufacturer: Biochem Pharmaceutical Industries
Salt Composition : Pioglitazone(15mg), Metformin(500mg)
Strip of 10 Tablet
(Inclusive of all taxes)
Bioglita M 15 mg/500 mg Tablet should be taken in the dose and duration as advised by your doctor. It must be taken with food to avoid stomach upset. If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose. Overdose may lead to low blood sugar (hypoglycemia).
Bioglita M 15 mg/500 mg Tablet is a medicine that helps to control high blood glucose (sugar) levels. It helps get rid of extra glucose from your body through urine. It also improves the body’s response to the hormone insulin, which is responsible for regulating blood glucose (sugar) levels in our body.
Pioglitazone is a thiazolidinedione that increases insulin sensitivity in target tissues. It is well-absorbed, with a mean absolute bioavailability of 83% and reaching maximum concentrations in around 1.5 hours. It is metabolised by the hepatic cytochrome P450 enzyme system.Metformin has an oral bioavailability of 50–60% under fasting conditions, and is absorbed slowly. Peak plasma concentrations (Cmax) are reached within 1–3 hours of taking immediate-release metformin and 4–8 hours with extended-release formulations.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Bioglita M
Headache
Dizziness
Hypoglycemia (low blood glucose level)
Diarrhea
Nausea
Vomiting
Flatulence
Urinary tract infection
Upper respiratory tract infection
Edema (swelling)
You should not use metformin and pioglitazone if you have severe heart failure, severe kidney disease, active bladder cancer, metabolic acidosis, or ketoacidosis (call your doctor for treatment). Metformin and pioglitazone can cause or worsen congestive heart failure.
Bioglita M 15 mg/500 mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is unsafe to consume alcohol with Bioglita M 15 mg/500 mg Tablet.
Bioglita M 15 mg/500 mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Use with caution
Below 9years: Contraindicated
Pioglitazone and metformin combination is used with proper diet and exercise to treat high blood sugar levels caused by type 2 diabetes. Pioglitazone works by helping your body use insulin better.
If you use other drugs or over the counter products at the same time, the effects of Bioglita M Tablet may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. Bioglita M Tablet may interact with the following drugs and products:
Anti-diabetic drugs
Beta blockers
Furosemide
Gatifloxacin
Gemfibrozil
Leflunomide
Lomitapide
Mipomersen
Prednisone
Rifampin
Do not chew, crush or break it. Bioglita M 15 mg/500 mg Tablet is to be taken with food.
Store below 30°C
If you miss a dose of Bioglita M 15 mg/500 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Take it as per the dose and duration prescribed by your doctor.
Monitor your blood sugar level regularly while you are taking this medicine.
It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms such as cold sweats, cool pale skin, tremor, and anxiety.
Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).
Inform your doctor if you notice weight gain, shortness of breath, irregular heartbeat, or any abnormal swelling.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Bioglita M 15 mg/500 mg Tablet is to be taken with food.
