Manufacturer: Biochem Pharmaceutical Industries
Salt Composition : Methotrexate(500mg)
Biotrexate 500mg Injection is given under the supervision of a healthcare professional and should not be self-administered. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. You should avoid drinking alcohol as it may increase your risk of liver damage.
The composition of Biotrexate Injection works by stopping or slowing down the growth of cancer cells and suppressing the immune system.
Methotrexate is mainly excreted by the kidney as intact drug regardless of the route of administration. The drug is filtered by the glomeruli, and then undergoes both secretion and reabsorption processes within the tubule.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Biotrexate
Abdominal pain
Indigestion
Loss of appetite
Nausea
Vomiting
Tiredness
Mouth sore
a bad infection.
dehydration.
condition resulting from a defective immune system.
low blood counts due to bone marrow failure.
anemia.
decreased blood platelets.
low levels of white blood cells.
low levels of a type of white blood cell called neutrophils.
Biotrexate 500mg Injection is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Caution is advised when consuming alcohol with Biotrexate 500mg Injection. Please consult your doctor.
Biotrexate 500mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Use with caution
Below 9years: Contraindicated
Methotrexate is indicated in the management of selected adults with severe, active, rheumatoid arthritis (ACR criteria), or children with active polyarticular-course juvenile rheumatoid arthritis, who have had an insufficient therapeutic response to, or are intolerant of, an adequate trial of first-line therapy
infections.
liver disease.
myelosuppression.
renal dysfunction.
stomatitis.
Kindly do not self administer.
Store below 25°C
If you miss a dose of Biotrexate 500mg Injection, please consult your doctor.
Consult a doctor before taking any medicines.
Biotrexate 500mg Injection helps treat various types of cancer such as blood cancer, bone cancer, non-Hodgkin lymphoma (NHL), breast cancer, lung cancer, head and neck cancer, cervical cancer, ovarian cancer and testicular cancer.
Take it once a week, on the same day every week.
Drink plenty of liquids to stay hydrated while taking this medication.
Always take folic acid as advised by your doctor. This will help lessen the side effects of this medicine.
It may take 6 to 8 weeks for Biotrexate 500mg Injection to work. Keep taking the medication as prescribed.
Avoid drinking alcohol while taking this medicine as it may increase the risk of side effects.
It can be harmful to an unborn baby. Avoid pregnancy for at least 6 months after your last dose.
Your doctor may get regular blood test done to monitor your kidney function, liver function and level of blood cells in your blood.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
