Manufacturer: Mankind Pharma Ltd
Salt Composition : Amlodipine(5mg), Bisoprolol(2.5mg)
Packet of 10 Tablet
(Inclusive of all taxes)
Bisoheart AM 5mg / 2.5mg Tablet is a medicine used to treat hypertension (high blood pressure). It is a combination of two medicines that effectively controls blood pressure when a single medication is not effective. It helps to lower high blood pressure and thus reduces the chances of future heart attack and stroke. It should be taken empty stomach preferably in the morning at a fixed time every day. This medicine should not be stopped abruptly as it may result in sudden increase of blood pressure. It should be used along with a proper diet, salt restriction, and regular exercise for best results. Some patients may develop swelling of ankle as a side effect of this medicine. It may also produce dizziness initially, but this improves with time.
Bisoheart AM 5mg / 2.5mg Tablet contains Amlodipine (calcium channel blocker) that acts by relaxing the blood vessels. This reduces the workload on the heart and makes the heart more efficient at pumping blood throughout the body.
Amlodipine is a dihydropyridine calcium antagonist drug with distinctive pharmacokinetic characteristics which appear to be attributable to a high degree of ionisation. Following oral administration, bioavailability is 60 to 65% and plasma concentrations rise gradually to peak 6 to 8h after administration.Bisoprolol exhibits a high absolute bioavailability (90%) because of its nearly complete absorption (greater than 90%) and small first-pass effect (10%). Bioavailability is independent of food intake. A long plasma-elimination half-life (10-11h) allows a once-a-day dose regimen.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Bisoheart-AM
Headache
Edema (swelling)
Fatigue
Dizziness
Hypersensitivity to Bisoheart AM 5mg / 2.5mg Tablet is a contraindication. In addition, Bisoheart AM 5mg / 2.5mg Tablet should not be used if you have the following conditions:
Allergic to bisoprolol
Bradycardia (heart rate less than 60)
Cardiogenic shock
Hypersensitivity
Overt cardiac failure
Second or third degree heart block
Bisoheart AM 5mg / 2.5mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is unsafe to consume alcohol with Bisoheart AM 5mg / 2.5mg Tablet.
Bisoheart AM 5mg / 2.5mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Use with caution
Below 9years: Contraindicated
Amlodipine + Bisoprolol is a combination of two medicines: Amlodipine and Bisoprolol, which lowers blood pressure effectively. Amlodipine is a calcium channel blocker which works by relaxing blood vessels while bisoprolol is a beta blocker that works specifically on the heart to slow down the heart rate.
If you use other drugs or over the counter products at the same time, the effects of Bisoheart AM 5mg / 2.5mg Tablet may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. Bisoheart AM 5mg / 2.5mg Tablet may interact with the following drugs and products:
Adrenaline
Amiodarone
CYP3A4 inhibitors
Cimetidine
Clonidine
Cyclosporine
Digoxin
Diltiazem
Indomethacin
Itraconazole
Do not chew, crush or break it. Bisoheart AM 5mg / 2.5mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Bisoheart AM 5mg / 2.5mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
You have been prescribed Bisoheart AM 5mg / 2.5mg Tablet for the treatment of high blood pressure.
Lowering blood pressure reduces chance of future heart attack & strokes.
It may cause dizziness. Get up slowly when rising from a sitting or lying position.
Do not stop taking the medication suddenly without talking to your doctor as it can cause sudden increase in your blood pressure.
Let your doctor know if you are pregnant or planning for pregnancy.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Bisoheart AM 5mg / 2.5mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Q. Can I feel dizzy after taking Bisoheart AM 5mg / 2.5mg Tablet?
Yes, the use of Bisoheart AM 5mg / 2.5mg Tablet can make you feel dizzy. This may occur when you suddenly rise up from lying or sitting position. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
Q. Can I stop taking Bisoheart AM 5mg / 2.5mg Tablet if I feel well?
No, keep using Bisoheart AM 5mg / 2.5mg Tablet as advised by your doctor, even if you feel well. Stopping Bisoheart AM 5mg / 2.5mg Tablet suddenly may lead to serious complications such as heart attack and stroke.
Q. What are the instructions for the storage and disposal of Bisoheart AM 5mg / 2.5mg Tablet?
Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Q. What are the contraindications associated with the use of Bisoheart AM 5mg / 2.5mg Tablet?
Bisoheart AM 5mg / 2.5mg Tablet is considered to be harmful for patients who are allergic to amlodipine, bisoprolol or any of its ingredients. It should be avoided in patients with a history of asthma or lung disease. Inform your doctor about your medical history and the medicines you might be taking.
Q. Can the use of Bisoheart AM 5mg / 2.5mg Tablet cause headache?
Yes, the use of Bisoheart AM 5mg / 2.5mg Tablet can cause headaches at the beginning of the treatment. Headaches usually go away after the first week of the treatment. Contact your doctor if the headaches are frequent and do not go away.
