Manufacturer: Khandelwal Laboratories Pvt Ltd
Salt Composition : Bleomycin(15IU)
Bleocin Injection may be used alone or with other medicines as part of combination therapy. It is given under the supervision of a healthcare professional and should not be self-administered. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. You should avoid drinking alcohol as it may increase your risk of liver damage.
Bleomycin, a non-heme iron protein, acts by induction of DNA strand breaks. Some studies suggest bleomycin also inhibits incorporation of thymidine into DNA strands. DNA cleavage by bleomycin depends on oxygen and metal ions, at least in vitro.
In humans, bleomycin is rapidly eliminated primarily by renal excretion. This accounts for approximately half of a dose. In patients with renal compromise or extensive prior cisplatin therapy, the drug half-life can extend from 2 to 4 hours up to 21 hours.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Bleocin
Fever
Hair loss
Interstitial pneumonia
Loss of appetite
Low blood platelets
Nail discoloration
Nausea
Pulmonary fibrosis
Rigors
Scratch dermatitis
Skin pigmentation
Stomatitis (Inflammation of the mouth)
Vomiting
Weight loss
a type of inflammation of the lung called interstitial pneumonitis.
a condition where there is formation of fibrous tissue in the lung called pulmonary fibrosis.
pregnancy.
a patient who is producing milk and breastfeeding.
chronic obstructive pulmonary disease.
Bleocin Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
It is not known whether it is safe to consume alcohol with Bleocin Injection. Please consult your doctor.
Bleocin Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Use with caution
Below 9years: Contraindicated
Bleomycin belongs to the general group of medicines called antineoplastics. It is used to treat several types of cancer, including cervix and uterus cancer, head and neck cancer, testicle and penile cancer, and certain types of lymphoma.
BLEOMYCIN interacts with other anti-cancer medicines (carmustine, mitomycin, cyclophosphamide, gemcitabine, Cisplatin), a medicine for cardiac disorders (acetyldigoxin), a medicine for epilepsy (Phenytoin), a medicine for schizophrenia (Clozapine), antibiotic (Gentamicin, amikacin, and ticarcillin), medicines that reduce the efficacy of immune system (cyclosporine and tacrolimus) and live vaccines (e.g., rubella, mumps, measles, shingles).
Kindly do not self administer.
Store in a refrigerator (2 - 8°C). Do not freeze.
If you miss a dose of Bleocin Injection, please consult your doctor.
Consult a doctor before taking any medicines.
Bleocin Injection is given as an injection into the veins, muscles or under the skin by the healthcare provider.
Do not skip any dose and complete the course as suggested by your doctor.
Use an effective method of birth control to avoid pregnancy while taking this medication.
You may need to have blood tests to monitor your blood cells, liver function and kidney function during treatment.
Inform your doctor immediately if you experience coughing, shortness of breath and cracking sound while breathing.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. What does Bleocin Injection treat?
Bleocin Injection is used to treat squamous cell cancers, certain types of blood cancers, skin cancers and cancer of the thyroid, bladder, lungs, abdomen or genitals.
Q. Does Bleocin Injection cause pulmonary fibrosis, nausea or hair loss?
Yes. Bleocin Injection may cause pulmonary fibrosis, nausea and hair loss. If you notice any such symptoms, please consult your doctor.
Q. How does Bleocin Injection cause pulmonary fibrosis?
Pulmonary fibrosis (scarring of the tissue of the lungs) is one of the side effects of Bleocin Injection. It is reportedly caused by lack of an enzyme that metabolises Bleocin Injection in the lungs.
