Manufacturer: Alkem Laboratories Ltd
Salt Composition : Everolimus(10mg)
Boletraaz 10mg Tablet must be taken in a dose and duration as per the prescription. It can be taken with or without food but make sure to take it at about the same time every day. An overdose of this medicine may have serious side effects on the body.The common side effects of this medicine are weakness, sinus inflammation, infection, fever, cough, etc. If any of the side effects persist or bother you, consult the doctor immediately. Inform the doctor immediately if you experience any allergic reactions (rash, shortness of breath, coughing, swelling, etc.). Always seek medical advice if you have increased thirst or increased frequency of urination, suffer from shortness of breath, cough or fever, or need to receive any vaccination after taking this medication.
Everolimus has a mechanism of action similar to that of sirolimus. It blocks growth-driven transduction signals in the T-cell response to alloantigen and thus acts at a later stage than the calcineurin inhibitors ciclosporin and tacrolimus.
Oral everolimus is absorbed rapidly, and reaches peak concentration after 1.3-1.8 hours. Steady state is reached within 7 days, and steady-state peak and trough concentrations, and area under the concentration-time curve (AUC), are proportional to dosage.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Boletraaz
Weakness
Sinus inflammation
Infection
Fever
Cough
Fatigue
Stomatitis (Inflammation of the mouth)
Otitis media (infection of ear)
Diarrhea
Upper respiratory tract infection
a bad infection.
cancer or malignancy.
diabetes.
high cholesterol.
high amount of triglyceride in the blood.
hemolytic uremic syndrome, a condition that affects the kidney and the blood.
anemia.
decreased blood platelets.
Boletraaz 10mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
It is not known whether it is safe to consume alcohol with Boletraaz 10mg Tablet. Please consult your doctor.
Boletraaz 10mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Use with caution
Below 9years: Contraindicated
Everolimus is indicated for the treatment of postmenopausal women with advanced hormone receptor-positive, HER2-negative breast cancer in combination with exemestane after failure of treatment with letrozole or anastrozole.
liver disease.
vaccination.
renal disease.
hematologic abnormalities.
blood glucose.
cholesterol.
Infections.
wound complication.
Do not chew, crush or break it. Boletraaz 10mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Boletraaz 10mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Boletraaz 10mg Tablet is given for the treatment of certain cancers and to prevent organ transplant rejection.
Boletraaz 10mg Tablet may affect male or female fertility; consult your doctor if you are planning to have a child.
Inform your doctor straight away if you think you are getting a sore throat or if you have a high temperature. This is because Boletraaz 10mg Tablet increases your risk of getting an infection.
While you are taking Boletraaz 10mg Tablet do not take any vaccinations without talking to your doctor first.
If you are having an operation or dental treatment, always tell the person carrying out the treatment that you are taking Boletraaz 10mg Tablet.
Do not drink grapefruit juice while you are taking this medicine. This is because a chemical in grapefruit juice can interfere with the action of Boletraaz 10mg Tablet.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Boletraaz 10mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Q. Is any monitoring required while taking Boletraaz 10mg Tablet?
Regular monitoring is required while you are on Boletraaz 10mg Tablet. The doctor will advise blood tests to see the counts of red blood cells, white blood cells, and platelets since the counts may decrease during treatment with Boletraaz 10mg Tablet. Also, blood tests will be required to check your kidney function, liver function, blood glucose levels, and cholesterol levels.
Q. What should I avoid while taking Boletraaz 10mg Tablet?
You should avoid grapefruit or grapefruit juice while taking Boletraaz 10mg Tablet. This is because taking them together may increase the levels of Boletraaz 10mg Tablet in your blood to harmful levels. Avoid the use of live vaccinations and any possible contact with individuals who have received live vaccinations.
Q. What is the most important information I need to know about Boletraaz 10mg Tablet?
Boletraaz 10mg Tablet can cause serious side effects which include severe allergic reactions, angioedema, and kidney failure which can be severe and can lead to death. It is possible that you may develop an infection or problems related to lung such as breathing problems.
Q. Is Boletraaz 10mg Tablet a chemotherapy?
Boletraaz 10mg Tablet is an anticancer medicine. It belongs to kinase inhibitor class of medicines. It works by reducing the blood supply to the tumor, which slows down the growth and spread of cancer cells.
Q. How is Boletraaz 10mg Tablet administered?
Usually, Boletraaz 10mg Tablet is taken once or twice daily. The medicine should always either be taken with food or always be taken without food. Boletraaz 10mg Tablet should be swallowed whole with water and should not be crushed or chewed.
Q. How long can you take Boletraaz 10mg Tablet?
There is no definite duration of treatment with Boletraaz 10mg Tablet. Boletraaz 10mg Tablet is continued till clinical benefit is seen or unacceptable toxicity or side effects occur.
Q. How will I know that Boletraaz 10mg Tablet is shrinking my brain tumor?
The effect of Boletraaz 10mg Tablet in shrinking the size of tumor can only be checked by getting regular brain scans. It should be done as advised by your doctor and your treatment plan.
Q. Is Boletraaz 10mg Tablet cytotoxic?
Yes, Boletraaz 10mg Tablet is cytotoxic against human cancer cells of breast, stomach, prostate, and kidneys (renal cell carcinoma).
