Manufacturer: Natco Pharma Ltd
Salt Composition : Bosentan(62.5mg)
Bosenat 62.5 Tablet should be taken with or without food. This medicine should be used regularly to get the most benefit from it. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed for you.
Bosentas 62.5 Tablet 10's is an anti-hypertension medication primarily used to treat pulmonary arterial hypertension. It works by blocking the action of endothelin. Endothelin narrows the blood vessels and increases the pressure in the blood vessels of the lungs.
The pharmacokinetics of bosentan are dose-proportional up to 600 mg (single dose) and 500 mg/day (multiple doses). The pharmacokinetics of bosentan in paediatric PAH patients are comparable to those in healthy subjects, whereas adult PAH patients show a 2-fold increased exposure.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Bosenat
Headache
Ankle swelling
Edema (swelling)
Diarrhea
Anemia (low number of red blood cells)
Respiratory tract infection
anemia.
decreased blood platelets.
sudden and serious symptoms of heart failure called acute decompensated heart failure.
fluid in the lungs.
liver problems.
severe liver disease.
visible water retention.
high amount of bilirubin in the blood.
Bosenat 62.5 Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Bosenat 62.5 Tablet may cause excessive drowsiness with alcohol.
Bosenat 62.5 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Use with caution
Below 9years: Contraindicated
Bosentan is used to treat pulmonary arterial hypertension (PAH, high blood pressure in the vessels that carry blood to the lungs) in adults and children 3 years of age and older. Bosentan may improve the ability to exercise and slow the worsening of symptoms in patients with PAH.
hepatotoxicity/liver impairment.
anemia.
fluid retention.
Do not chew, crush or break it. Bosenat 62.5 Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Bosenat 62.5 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Your doctor has prescribed Bosenat 62.5 Tablet to treat high pressure in the blood vessels that carry blood from the heart to the lungs (the pulmonary arteries).
It helps improve your quality of life, exercising ability, and delay disease progression.
Notify your doctor if you are pregnant or planning to conceive or breastfeeding.
Your doctor may ask you to get routine blood tests done to check for anemia and to assess the functioning of your liver.
Do not drive or do anything requiring concentration until you know how Bosenat 62.5 Tablet affects you.
Females with reproductive potential should use a reliable form of birth control while using and 1 month after stopping Bosenat 62.5 Tablet as it is toxic to an unborn baby.
Inform your doctor if you notice weight gain, swelling of your arms and legs, or difficulty breathing.
Inform your doctor if you notice yellowing of skin/eye, dark urine, or stomach pain.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Bosenat 62.5 Tablet may be taken with or without food, but it is better to take it at a fixed time.
Q. How is Bosenat 62.5 Tablet administered?
Bosenat 62.5 Tablet is given as a tablet form and can be taken with or without food. The tablets are to be taken twice daily in the morning and evening. The exact dosage and frequency of dose will be decided by the doctor on the basis of age and weight of the patient.
Q. Are there chances of anemia with Bosenat 62.5 Tablet?
Yes, there are chances that Bosenat 62.5 Tablet may cause anemia. It can cause a dose-related decrease in hemoglobin in the blood which could lead to anemia. Regular hemoglobin check is advised while taking this medicine and consult your prescribing doctor for his advice. In some cases, blood transfusion is done to treat anemia.
Q. Can I take Bosenat 62.5 Tablet if I have liver problems?
It has been found that in some cases Bosenat 62.5 Tablet can cause liver damage in patients who are prone to have liver disease. This medicine can also lead to increased liver enzymes. Hence, it should be used with caution in prone patients or in patients with history of liver disease. Before starting the medication inform your doctor if you have had a history of liver disease.
Q. Is Bosenat 62.5 Tablet safe in pregnancy?
No, Bosenat 62.5 Tablet is not safe during pregnancy. There is evidence to show that it can cause major birth defects in the newborn baby and can harm the baby in womb. It is not advised to take Bosenat 62.5 Tablet if you are planning to become pregnant. You should use reliable contraception methods while you take Bosenat 62.5 Tablet. Consult your doctor before starting this medication or planning pregnancy.
