Manufacturer: Sun Pharmaceutical Industries Ltd
Salt Composition : Timolol(5mg), Brimonidine(1.5mg)
Brimolol Eye Drop is to be used only in the affected eye in the dose and duration as advised by the doctor. Wash your hands before using this medicine. Check the label thoroughly for directions before use. Do not skip any doses and finish the full course of treatment even if you feel better.
They work by decreasing the raised intraocular (inside the eye). Brimonidine has the dual action of reducing the aqueous humour fluid (fluid in the front part of the eye) production and increasing the outflow of aqueous fluid.
Timolol maleate can exert pharmacological actions for as long as 24 hours if given in the 0.5% or 0.25% doses. Timolol competes with adrenergic neurotransmitters for binding to beta(1)-adrenergic receptors in the heart and the beta(2)-receptors in the vascular and bronchial smooth muscle.After ocular administration of either a 0.1% or 0.2% solution, plasma concentrations peaked within 0.5 to 2.5 hours and declined with a systemic half-life of approximately 2 hours. In humans, systemic metabolism of brimonidine is extensive. It is metabolized primarily by the liver.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Brimolol
Application site reactions (burning, irritation, itching and redness)
Blurred vision
Hypersensitivity to Brimolol Eye Drops is a contraindication. In addition, Brimolol Eye Drops should not be used if you have the following conditions:
Children under the age of 2
Hypersensitivity
Monoamine oxidase inhibitors therapy
Pregnancy
Information regarding the use of Brimolol Eye Drop during pregnancy is not available. Please consult your doctor.
No interaction found/established
Information regarding the use of Brimolol Eye Drop during breastfeeding is not available. Please consult your doctor.
Use with caution
Below 9years: Contraindicated
This combination medication is used to treat high pressure inside the eye due to glaucoma (open-angle type) or other eye diseases (such as ocular hypertension). Lowering high pressure inside the eye helps to prevent blindness. This product contains brimonidine and timolol.
If you use other drugs or over the counter products at the same time, the effects of Brimolol Eye Drops may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. Brimolol Eye Drops may interact with the following drugs and products:
Acetaminophen
Alcohol
Ascorbic acid
Aspirin
Atorvastatin
Cholecalciferol
Clopidogrel
Cyanocobalamin
Digoxin
Furosemide
Check the label for directions before use. Hold the dropper close to the eye without touching it. Gently squeeze the dropper and place the medicine inside the lower eyelid. Wipe off extra liquid.
Store below 30°C
If you miss a dose of Brimolol Eye Drop, skip it and continue with your normal schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Brimolol Eye Drop is a combination of two medicines that lowers high pressure in the eye and reduces the risk of vision loss.
Apply pressure on the corner of the eye (close to the nose) for about 1 minute, immediately after instilling the drop.
If you wear soft contact lenses, remove them before putting in these eye drops and wait at least 15 minutes before putting your lenses back in.
Do not touch the tip of the dropper to any surface, or to your eye, to avoid contaminating the eye drops.
Wait for at least 5-10 minutes before delivering the next medication in the same eye to avoid dilution.
It may cause short term blurring of vision when first used. Use caution before driving or using machines.
It may cause temporary burning or itching sensation in the eye. Inform your doctor if this does not go away.
Make sure to use within 4 weeks of opening the bottle.
This medicine is for external use only. Take it in the dose and duration as advised by your doctor. Check the label for directions before use. Hold the dropper close to the eye without touching it. Gently squeeze the dropper and place the medicine inside the lower eyelid. Wipe off extra liquid.
Q. How to use Brimolol Eye Drop?
Wash your hands before applying Brimolol Eye Drop to avoid contamination, and do not touch the tip of the dropper. If you wear contact lenses, remove them before using Brimolol Eye Drop. For applying Brimolol Eye Drop, tilt your head back, look up, and pull down the lower eyelid to make a pouch and then put the drops in the pouch.
Q. Can Brimolol Eye Drop be stopped when symptoms are relieved?
No, Brimolol Eye Drop should be continued as advised by the doctor. If any problems are experienced due to the use of Brimolol Eye Drop, consult the doctor for re-evaluation.
Q. Can the use of Brimolol Eye Drop cause blurry vision?
Brimolol Eye Drop can blur your eyes for a short period of time. Avoid driving or operating machinery just after using Brimolol Eye Drop.
Q. What are the instructions for the storage and disposal of Brimolol Eye Drop?
Keep this medicine in the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Q. What are the contraindications associated with the use of Brimolol Eye Drop?
Brimolol Eye Drop should not be used by patients who are hypersensitive to Timolol, Brimonidine or any of its constituents. This medicine should be avoided in patients who have airway disease, lung disease or heart disease. This medicine should not be used in children who are 2 years old or younger.
