Manufacturer: Ajanta Pharma Ltd
Salt Composition : Brinzolamide(1% w/v), Brimonidine(0.2% w/v)
Brivex Eye Drop is to be used only in the affected eye in the dose and duration as advised by the doctor. Wash your hands before using this medicine. It is advised to check the label for directions before use. Do not skip any doses and finish the full course of treatment even if you feel better.
Brivex Eye Drop is a prescription medicine having a combination of medicines that is used to treat glaucoma. It works by decreasing the pressure of fluid in the eye (aqueous humor), which helps in lowering the increased eye pressure.
After ocular administration of either a 0.1% or 0.2% solution, plasma concentrations peaked within 0.5 to 2.5 hours and declined with a systemic half-life of approximately 2 hours. In humans, systemic metabolism of brimonidine is extensive. It is metabolized primarily by the liver.Brinzolamide is a topical carbonic anhydrase inhibitor which reduces the production of aqueous humor in the ciliary body, thereby reducing intra-ocular pressure. It is formulated as an ophthalmic suspension. The pharmacokinetics of ocular suspensions is not well understood.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Brivex
Application site reactions (burning, irritation, itching and redness)
Blurred vision
Hypersensitivity to Brivex Eye Drops is a contraindication. In addition, Brivex Eye Drops should not be used if you have the following conditions:
Adolescents under the age of 18 years
Allergic
Children
Children under the age of 2
Fever
Hypersensitivity
Infants
Infected eyes
Kidney problem
Monoamine oxidase inhibitors therapy
Information regarding the use of Brivex Eye Drop during pregnancy is not available. Please consult your doctor.
No interaction found/established
Information regarding the use of Brivex Eye Drop during breastfeeding is not available. Please consult your doctor.
Use with caution
Below 9years: Contraindicated
Brimonidine and brinzolamide ophthalmic (eye) drops is used to treat increased pressure in the eye caused by open-angle glaucoma or a condition called ocular hypertension. Both eye conditions are caused by high pressure in your eye and can lead to pain from pressure in your eye and then can eventually harm your vision.
If you use other drugs or over the counter products at the same time, the effects of Brivex Eye Drops may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. Brivex Eye Drops may interact with the following drugs and products:
Acetaminophen
Acetazolamide
Alcohol
Ascorbic acid
Aspirin
Atorvastatin
Cholecalciferol
Clopidogrel
Cyanocobalamin
Dichlorphenamide
Check the label for directions before use. Hold the dropper close to the eye without touching it. Gently squeeze the dropper and place the medicine inside the lower eyelid. Wipe off the extra liquid.
Store below 25°C
If you miss a dose of Brivex Eye Drop, skip it and continue with your normal schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Brivex Eye Drop is a combination of two medicines that lowers high pressure in the eye and reduces the risk of vision loss.
Apply pressure on the corner of the eye (close to the nose) for about 1 minute, immediately after instilling the drop.
If you wear soft contact lenses, remove them before putting in these eye drops and wait at least 15 minutes before putting your lenses back in.
Do not touch the tip of the dropper to any surface, or to your eye, to avoid contaminating the eye drops.
Wait for at least 5-10 minutes before delivering the next medication in the same eye to avoid dilution.
It may cause short term blurring of vision when first used. Use caution before driving or using machines.
It may cause temporary burning or itching sensation in the eye. Inform your doctor if this does not go away.
Make sure to use within 4 weeks of opening the bottle.
This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Hold the dropper close to the eye without touching it. Gently squeeze the dropper and place the medicine inside the lower eyelid. Wipe off the extra liquid.
