Manufacturer: Celon Laboratories Ltd
Salt Composition : Busulfan(60mg)
Bucelon 60mg Injection is given as an injection into veins by the healthcare provider. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Bucelon 60mg Injection is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication.
In summary, intravenous busulfan has highly predictable, linear pharmacokinetics from 32 mg/m2 (approximately 0.8 mg/kg) to 130 mg/m2 (approximately 3.2 mg/kg). Further, once-daily intravenous busulfan dosing is convenient, favoring its more widespread application.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Bucelon
Decreased blood cells (red cells, white cells, and platelets)
Nausea
Abdominal pain
Vomiting
Loss of appetite
Anxiety
Decreased magnesium level in blood
Decreased potassium level in blood
Diarrhea
Fever
Headache
Increased glucose level in blood
Insomnia (difficulty in sleeping)
Stomatitis (Inflammation of the mouth)
Hypersensitivity to Bucelon Injection is a contraindication. In addition, Bucelon Injection should not be used if you have the following conditions:
Acute leukemia
Anemia
Blockage or closing off of blood vessels in the liver
Bone marrow suppression
Chronic lymphocytic leukemia
Chronic myelogenous leukemia blast crisis
Decreased Neutrophils a type of white blood cell
Decreased blood platelets
Doubtful chronic myelogenous leukemia diagnosis
Epileptic Seizure
Bucelon 60mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
It is not known whether it is safe to consume alcohol with Bucelon 60mg Injection. Please consult your doctor.
Bucelon 60mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Use with caution Below 9years: Contraindicated
Chronic Myelogenous (Myeloid, Myelocytic, Granulocytic) Leukemia. Pre-medicate with anticonvulsants (e.g. benzodiazepines, phenytoin, valproic acid or levetiracetam) and antiemetic.
Brain Malignancies (Orphan).
Stem Cell Transplantation (Orphan).
Hepatic Impairment.
Renal Impairment.
Other Indications & Uses.
If you use other drugs or over the counter products at the same time, the effects of Bucelon Injection may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. Bucelon Injection may interact with the following drugs and products:
Cyclophosphamide
Itraconazole
Phenytoin
Kindly do not self administer.
Store in a refrigerator (2 - 8°C). Do not freeze.
If you miss a dose of Bucelon 60mg Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Bucelon 60mg Injection is given as an injection into the vein by a healthcare provider.
Do not skip any dose and complete the course as suggested by your doctor.
Use an effective method of birth control to avoid pregnancy while taking this medication.
Your doctor may get regular blood tests done to monitor the levels of blood cells in your blood.
Inform your doctor immediately if you notice unusual bruising or bleeding or if you have dark, tarry, or bloody stools and sore throat.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. Does Bucelon 60mg Injection cause hair loss?
Yes, Bucelon 60mg Injection can cause hair loss.
Q. Is Bucelon 60mg Injection a vesicant?
Yes. Bucelon 60mg Injection is a vesicant (irritant).
