Manufacturer: Ornate Labs Pvt Ltd
Salt Composition : Ibuprofen(400mg), Paracetamol(325mg)
Buflam 400mg/325mg Tablet is best taken with food to reduce side effects. The dose and how often you need it will be decided by your doctor. You should take it regularly as advised by your doctor. Medicines used to treat pain are usually best taken at the first sign of pain. It is meant for short-term use only. Consult your doctor if the symptoms persist or worsen or if the medicine is required for use beyond 3 days.
This medicine acts on the brain centers responsible for regulating the body temperature to reduce elevated temperatures. It also inhibits the synthesis and release of certain natural substances responsible for causing pain and swelling.
After oral administration, peak serum concentration is reached after 1–2 hours, and up to 99% of the drug is bound to plasma proteins. The majority of ibuprofen is metabolized and eliminated within 24 hours in the urine; however, 1% of the unchanged drug is removed through biliary excretion.It distributes rapidly and evenly throughout most tissues and fluids and has a volume of distribution of approximately 0.9L/kg. 10 to 20% of the drug is bound to red blood cells. Paracetamol is extensively metabolised (predominantly in the liver), the major metabolites being the sulphate and glucuronide conjugates.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Buflam
Heartburn
Indigestion
Nausea
Stomach pain
Hypersensitivity to Buflam 400mg/325mg Tablet is a contraindication. In addition, Buflam 400mg/325mg Tablet should not be used if you have the following conditions :
Active appendicitis
Aspirin
Pregnant
Gastrointestinal bleeding
Hypersensitivity
For babies born with congenital heart disease
Breastfeeding
Hepatic impairment
Buflam 400mg/325mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is unsafe to consume alcohol with Buflam 400mg/325mg Tablet.
Buflam 400mg/325mg Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Use with caution Below 9years: Contraindicated
Ibuprofen+Paracetamol is used for pain relief and fever. It relieves pain in conditions like headache, mild migraine, muscle pain, dental pain, rheumatoid arthritis, ankylosing spondylitis, osteoarthritis or painful menses. Ibuprofen + Paracetamol is a combination of two medicines: Ibuprofen and Paracetamol.
If you use other drugs or over the counter products at the same time , the effects of Buflam 400mg/325mg Tablet may change. This increases the risk of side effects or drug malfunction. Tell your doctor about all the medications, vitamins and herbal medicines you are using so that your doctor can help prevent or manage drug interactions. Buflam 400mg/325mg Tablet may interact with the following drugs and products:
Alcohol
Aspirin
Corticosteroids
Cyclosporine
Interfere with certain laboratory tests
Juxtapid mipomersen
Ketoconazole
Leflunomide
Lithium drugs
Methotrexate
Do not chew, crush or break it. Buflam 400mg/325mg Tablet is to be taken with food.
Store below 30°C
If you miss a dose of Buflam 400mg/325mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
You have been prescribed this combination medicine to relieve pain, inflammation, and fever.
Take it with food to avoid getting an upset stomach.
Take it as per the dose and duration prescribed by your doctor. Long-term use may lead to stomach bleeding and kidney problems.
Avoid consuming alcohol when taking Buflam 400mg/325mg Tablet as it may cause excessive drowsiness and increase the risk of liver damage.
Do not take it with any other medicine containing paracetamol (drugs for pain/fever or cough and cold) without asking your doctor first.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Buflam 400mg/325mg Tablet is to be taken with food.
Q. Is it safe to use Buflam 400mg/325mg Tablet?
Buflam 400mg/325mg Tablet is safe for most patients. However, in some patients, it may cause some unwanted side effects like nausea, vomiting, stomach pain, heartburn and diarrhea. Inform your doctor if you experience any persistent problem due to this medication.
Q. Can I stop taking Buflam 400mg/325mg Tablet when my pain is relieved?
Buflam 400mg/325mg Tablet should be continued as advised by your doctor, if you are using the medicine for a condition associated with long-term pain. It can be discontinued if you are using it for short-term pain relief.
Q. Can the use of Buflam 400mg/325mg Tablet cause nausea and vomiting?
Yes, the use of Buflam 400mg/325mg Tablet may cause nausea and vomiting. Taking it with milk, food or antacids can prevent nausea. Avoid taking fatty or fried foods along with this medication. In case of vomiting, drink plenty of water or other fluids by taking small frequent sips. Talk to your doctor if vomiting persists and you notice signs of dehydration, like dark colored and strong-smelling urine or a low frequency of urination. Do not take any other medicines without speaking to your doctor.
Q. Can the use of Buflam 400mg/325mg Tablet cause dizziness?
Yes, the use of Buflam 400mg/325mg Tablet can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded, do not drive or use any machines. It is better to rest for sometime and resume once you feel better.
Q. Are there any specific contraindications associated with the use of Buflam 400mg/325mg Tablet?
The use of Buflam 400mg/325mg Tablet is considered to be harmful for patients with known allergy to any of the components of this medicine. It should be avoided in patients with known allergy to other painkillers (NSAIDs). The use of this medicine should preferably be avoided in patients with a history of stomach ulcers or in patients with active or recurrent stomach ulcer/bleeding. It should also be avoided in patients with history of heart failure, high blood pressure, and liver or kidney disease.
Q. Is Buflam 400mg/325mg Tablet helpful in relieving stomach pain?
No, Buflam 400mg/325mg Tablet should not be taken for stomach pain without consulting a physician. This drug can increase stomach acid secretion which may aggravate an unknown underlying condition.
Q. Can the use of Buflam 400mg/325mg Tablet cause damage to kidneys?
Yes, the long-term use of Buflam 400mg/325mg Tablet can cause damage to the kidneys. Normal kidneys produce a chemical called prostaglandins that protect the kidneys from damage. Use of painkillers lowers the levels of prostaglandins in the body, leading to kidney damage because of long-term use. Therefore, the use of painkillers is not recommended in patients with underlying kidney disease.
Q. Is it safe to take a higher than the recommended dose of Buflam 400mg/325mg Tablet ?
No, taking a higher than the recommended dose of Buflam 400mg/325mg Tablet can increase the risks of side effects like nausea, vomiting, heartburn, indigestion and diarrhea. In fact, using this medicine for a long-term can also damage your kidneys on long-term use. If you are experiencing increased severity of pain or if the pain is not relieved by the recommended doses of this medicine, please consult your doctor for re-evaluation.
