Buminate Infusion

Manufacturer: Baxter India Pvt Ltd

Salt Composition : Albumin(0.2)


Buminate Infusion must be administered under the supervision of a healthcare professional. You should not take it if you have any known allergies to this injection. Before taking it, inform the doctor you are suffering from any severe heart disease.Your doctor may check your blood pressure and ask you to get regular blood tests done while you are using this injection. The most common side effects include flushing, nausea, vomiting, chills, and fever.


Basic Information

Mechanism Of Action

Albumin in the Buminate Infusion replaces the blood or body fluids lost during excessive blood loss in certain conditions.

Pharmacokinets

Albumin is normally present in the blood and constitutes 50% to 60% of the plasma proteins and 80% to 85% of the oncotic pressure. Exogenously administered albumin increases the oncotic pressure of the intravascular system, pulling fluids from the interstitial space, thereby decreasing edema and increasing the circulating blood volume.

Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Buminate

Vomiting

Flushing (sense of warmth in the face, ears, neck and trunk)

Fever

Nausea

Chills

Hives

Slow heart rate

Contra Indications

significant anemia.

an increased risk of bleeding.

high blood pressure.

failure of the heart to maintain adequate circulation.

esophageal varices.

fluid in the lungs.

fluid overload.

cessation of urine production.

Pregnancy Related Information

Buminate Infusion may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.


Product And Alcohol Interaction

It is not known whether it is safe to consume alcohol with Buminate Infusion. Please consult your doctor.


Breast Feeding Related Information

Information regarding the use of Buminate Infusion during breastfeeding is not available. Please consult your doctor.


Children Related Information

Use with caution Below 9years: Contraindicated

Indications

Fluid resuscitation (should not be used as first line treatment – use crystalloids first)

Significant hypoalbuminemia.

Nephrotic syndrome.

Therapeutic plasma exchange.

Cardiothoracic surgery as a pump prime for cardiopulmonary bypass.

Interactions

Drug binds to some specific binding sites on human serum albumin.

Drug–albumin interactions are changed in diseased states.

Drug–drug interactions at the protein binding level are clinically used to enhance the efficacy of drugs.

Drug–albumin interactions are clinically applied to remove overdosed drugs.

Typical Dosage

Kindly do not self-administer.

Storage Requirements

Store in a refrigerator (2 - 8°C). Do not freeze.


Effects Of Missed Dosage

If you miss a dose of Buminate Infusion, please consult your doctor.


Effects Of Overdose

Consult a doctor before taking any medicines.

Expert Advice

It is given as an injection into veins under the supervision of a medical professional.

Inform your doctor immediately if you experience a skin rash, itching, breathing difficulties, swelling of face and changes in heartbeat while using this medicine.

Inform your doctor if you have history of severe anemia (lack of red blood cells), or severe heart failure.

How To Use

Your doctor or nurse will give you this medicine. Kindly do not self-administer.


FAQs

Q. What do you need to inform your doctor before you are given Buminate Infusion?

Before you are given this medicine, you need to inform your doctor if you are allergic to albumin preparations or to any of the other ingredients of this medicine. Suspicion of allergic or anaphylactic type reactions requires an immediate stop of the infusion.

Q. What vitals should be monitored before giving Buminate Infusion

Before giving this injection, your doctor or nurse will measure your blood pressure, heart rate and conduct blood tests to make sure you are not given an excess dose. If you experience a headache, difficulty in breathing, or increased blood pressure, inform your doctor immediately.

Q. How is Buminate Infusion given?

This medicine must be administered intravenously at a rate not to exceed 1 mL/min to patients with normal blood volume, due to the risk of developing circulatory overload and pulmonary edema (excess fluid in lungs).