Manufacturer: Zydus Cadila
Salt Composition : Cabazitaxel(60mg)
Cabtana 60mg Injection is given under the supervision of a healthcare professional and should not be self-administered. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. You should avoid drinking alcohol as it may increase your risk of liver damage.
Cabazitaxel is a microtubule inhibitor. Cabazitaxel binds to tubulin and promotes its assembly into microtubules while simultaneously inhibiting disassembly. This leads to the stabilization of microtubules, which results in the interference of mitotic and interphase cellular functions.
Cabazitaxel is excreted mainly into feces (76% of the administered dose) as approximately 20 metabolites, with a low urinary excretion (3.7% of the administered dose with 2.3% excreted as unchanged drug).
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Cabtana
Vomiting
Back pain
Weakness
Low blood platelets
Hair loss
Abdominal pain
Loss of appetite
Anemia (low number of red blood cells)
Diarrhea
Stomatitis (Inflammation of the mouth)
Blood in urine
Constipation
Cough
Taste change
Breathing problems
Decreased white blood cell count (neutrophils)
Nausea
Cabazitaxel is contraindicated in patients who have a history of severe hypersensitivity reactions to cabazitaxel or to other drugs formulated with polysorbate 80. Five patients experienced fatal infectious adverse events (sepsis or septic shock). All had grade 4 neutropenia and one had febrile neutropenia.
Cabtana 60mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
It is unsafe to consume alcohol with Cabtana 60mg Injection.
Cabtana 60mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Use with caution Below 9years: Contraindicated
Cabazitaxel is indicated in combination with prednisone for the treatment of patients with metastatic castration-resistant prostate cancer previously treated with a docetaxel-containing treatment regimen.
If you use other drugs or over the counter products at the same time, the effects of Cabtana Injection may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. Cabtana Injection may interact with the following drugs and products:
Abiraterone
Acetaminophen
Alprazolam
Aspirin
Carboplatin
Clotrimazole
Enzalutamide
Oxycodone
Pseudoephedrine
Triprolidine
Kindly do not self administer.
Store below 30°C
If you miss a dose of Cabtana 60mg Injection, please consult your doctor.
Consult a doctor before taking any medicines.
Cabtana 60mg Injection is given as an infusion into a vein (IV infusion) under the supervision of a doctor only.
Do not skip any dose and complete the course as suggested by your doctor.
Use an effective method of birth control to avoid pregnancy while taking this medication.
You may need to have blood tests to monitor your blood cells, platelets count, liver function and kidney function during treatment.
Inform your doctor immediately if you notice unusual bruising or bleeding or if you have dark, tarry, or bloody stools and sore throat.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. Is Cabtana 60mg Injection a vesicant or chemotherapeutic drug?
Cabtana 60mg Injection is a chemotherapeutic drug (drug used for the management of cancer). It is, however, not a vesicant (drug which causes severe blisters on the skin).
