Manufacturer: Cadila Pharmaceuticals Ltd
Salt Composition : Doxorubicin(Plain)(50mg)
It is given as a drip or infusion vein with extreme caution by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. It makes contraceptive pills less effective, so it advised to both male and female to use reliable contraception during the treatment.
Cadria 50mg Injection is an anti-cancer medication. It works by suppressing the activity of an enzyme (topoisomerase II) involved in DNA multiplication of the cancer cells. It also forms harmful chemicals (free radicals) which cause DNA damage. This slows the growth of cancer cells and eventually kills them.
Doxorubicin interacts with DNA by intercalation and inhibition of macromolecular biosynthesis. This inhibits the progression of topoisomerase II, an enzyme which relaxes supercoils in DNA for transcription.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Cadria
Vomiting
Allergic reaction
Nausea
Mouth sore
Hair loss
Stomach pain
Eye disorder
Increased thirst
Arrhythmia (irregular heartbeats)
Nail disorder
a bad infection.
glucose-6-phosphate dehydrogenase (G6PD) deficiency.
anemia.
decreased blood platelets.
low levels of a type of white blood cell called neutrophils.
heart attack within the last 30 days.
cardiomyopathy, a disease of the heart muscle.
Cadria 50mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
It is not known whether it is safe to consume alcohol with Cadria 50mg Injection. Please consult your doctor.
Cadria 50mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Use with caution Below 9years: Contraindicated
Cadria 50mg Injection is used in the treatment of various types of cancers of blood, breast, lung, ovaries and soft tissues. It can be used on its own, or sometimes given together with certain other medicines as part of combination chemotherapy.
If you use other drugs or over the counter products at the same time, the effects of Cadria Injection may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. Cadria Injection may interact with the following drugs and products:
Aprepitant
Cholecalciferol
Cyclophosphamide
Dexamethasone
Diphenhydramine
Docetaxel
Docusate
Esomeprazole
Hydromorphone
Loratadine
Kindly do not self administer.
Store in a refrigerator (2 - 8°C). Do not freeze.
If you miss a dose of Cadria 50mg Injection, please consult your doctor.
Consult a doctor before taking any medicines.
Cadria 50mg Injection is given as an injection into the vein under the supervision of a doctor.
Do not skip any dose and complete the course as suggested by your doctor.
Use an effective method of birth control to avoid pregnancy while taking this medication.
Your doctor may get regular blood tests done to monitor your electrolyte levels, liver function, blood cell count in your blood.
Inform your doctor if you experience fever, chills, shortness of breath and swelling of face or lips.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. How does doxorubicin work?
Doxorubicin is anti-cancer or antineoplastic chemotherapy drug that belongs to a class of medications called anthracyclines. It slows down or stops the growth of cancer cells by interfering with DNA of the cancer cells. This helps treat the cancer.
Q. Is doxorubicin a vesicant?
Yes doxorubicin is a vesicant (irritant).
