Manufacturer: Biocon
Salt Composition : Calcipotriol(0.005% w/v), Clobetasol(0.05% w/v)
Calpsor C Lotion should be used in the dose and duration as advised by your doctor. Wash your hands before using this medicine. It is advised to check the label for directions before use. It is for external use only.
Calcipotriol is a vitamin D derivative synthesized in 1985 by the Léo Laboratories. Its mode of action is identical to that of 1-25 vitamin D3 (calcitriol), essentially by regulating the activity of genes capable of responding to vitamin D.
Clobetasol propionate exerts its effect by binding to cytoplasmic glucocorticoid receptors and subsequently activates glucocorticoid receptor mediated gene expression. This results in synthesis of certain anti-inflammatory proteins, while inhibiting the synthesis of certain inflammatory mediators.
After application and systemic uptake, calcipotriol undergoes rapid hepatic metabolism. Calcipotriol is metabolized to MC1046 (the α,β−unsaturated ketone analog), which is subsequently metabolized to its primary metabolite, the saturated ketone analog MC1080,Clobetasol is under investigation for the treatment of Scleroderma. Clobetasol has been investigated for the prevention of Psoriasis and Cutaneous Atrophy Due to Corticosteroids. Clobetasol is a Corticosteroid. The mechanism of action of clobetasol is as a Corticosteroid Hormone Receptor Agonist.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Calpsor C
Itching
Rash
Corticosteroid hypersensitivity.
Cushing's syndrome, hepatic disease, hypothalamic-pituitary-adrenal (HPA) suppression, occlusive dressing, skin abrasion.
Diabetes mellitus.
Children, growth inhibition, increased intracranial pressure, infants, neonates.
Pregnancy.
Breast-feeding.
Calpsor C Lotion may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
No interaction found/established
Calpsor C Lotion is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Use with caution Below 5years: Contraindicated
Calcipotriol+Clobetasol is used in the treatment of psoriasis. Calcipotriol + Clobetasol is a combination of two medicines: Calcipotriol and Clobetasol which treat psoriasis. Calcipotriol is a form of vitamin D. It works by reducing the overproduction of skin cells that may build up and form scales on the skin.
CALCIPOTRIOL+CLOBETASOL may interact with corticosteroids (prednisone), drugs that lower the immune system (cyclosporine), and vitamins (Vitamin D).
Shake it well and apply to the area evenly.
Store below 25°C
If you miss a dose of Calpsor C Lotion, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Calpsor C Lotion is used to treat the redness, swelling, itching, and discomfort associated with psoriasis.
It is advisable to apply it once a day. For best effect, leave it on during the day if you have applied it in the morning, or overnight if you have used it in the evening.
Apply to the affected areas as a thin film two or three times daily, or as advised by your doctor.
Don't cover the area being treated with airtight dressings such as bandages unless directed by a doctor, as this may increase the risk of side effects.
If you are using a moisturizer along with this preparation, apply the moisturizer first. Then wait 10-15 minutes before applying Calpsor C Lotion.
Do not apply it on open wounds and cuts.
Your skin may become more sensitive to sunlight than normal while you are using Calpsor C Lotion. Try to avoid sitting out in the sun and do not use sunbeds.
Consult your doctor if your skin condition has not improved after 2 weeks of treatment.
This medicine is for external use only. Use this medicine in the dose and duration as advised by your doctor. Shake it well and apply to the area evenly.
