Manufacturer: Sun Pharmaceutical Industries Ltd
Salt Composition : Bicalutamide(50mg)
Caluran 50 CP Tablet should be taken with or without food, preferably at a fixed time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Caluran 50 CP Tablet is used in the treatment of cancer of the prostate gland. It may be also used to treat other conditions, as determined by the doctor. It works by blocking the effects of male hormones such as testosterone.
Bicalutamide is an androgen receptor inhibitor used to treat Stage D2 metastatic carcinoma of the prostate. Bicalutamide is an oral non-steroidal anti-androgen for prostate cancer. It is comprised of a racemic mixture that is a 50:50 composition of the (R)-bicalutamide and (S)-bicalutamide enantionmers.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Caluran
Anemia (low number of red blood cells)
Rash
Abdominal pain
Breast enlargement in male
Breast tenderness
Constipation
Decreased appetite
Decreased libido
Depression
Dizziness
Indigestion
Flatulence
Hot flashes
Increased liver enzymes
Nausea
Sleepiness
Weakness
Weight gain
diabetes.
anemia.
a type of inflammation of the lung called interstitial pneumonitis.
damage to the liver and inflammation.
liver problems.
abnormal liver function tests.
pregnancy.
Caluran 50 CP Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
It is not known whether it is safe to consume alcohol with Caluran 50 CP Tablet. Please consult your doctor.
Information regarding the use of Caluran 50 CP Tablet during breastfeeding is not available. Please consult your doctor.
Use with caution Below 5years: Contraindicated
Bicalutamide is used together with a luteinizing hormone releasing hormone (LHRH) analog (eg, goserelin or leuprolide) to treat stage D2 metastatic prostate cancer (cancer that has spread) in men. Bicalutamide belongs to the group of medicines called antiandrogens.
If you use other drugs or over the counter products at the same time, the effects of Caluran 50 CP Tablet may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. Caluran 50 CP Tablet may interact with the following drugs and products:
Atorvastatin
Midazolam
Other CYP3A4 substrates
Warfarin
Do not chew, crush or break it. Caluran 50 CP Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 25°C
If you miss a dose of Caluran 50 CP Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
You have been prescribed Caluran 50 CP Tablet for the treatment of prostate cancer.
Take it with or without food, preferably at the same time every day.
It may cause your skin to become light sensitive. Avoid direct exposure to excessive sunlight and use sunscreen when outdoors.
If you are diabetic, monitor your blood glucose regularly while taking Caluran 50 CP Tablet.
Your doctor may want you to have regular blood tests to monitor your liver function while you are taking this medicine. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
Do not stop taking the medication without talking to your doctor first.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Caluran 50 CP Tablet may be taken with or without food, but it is better to take it at a fixed time.
Q. Can Caluran 50 CP Tablet cause infertility?
There is limited data to support that Caluran 50 CP Tablet causes infertility. Caluran 50 CP Tablet has been shown to affect fertility in animals and therefore it is assumed that it may cause fertility on humans. Some studies have shown that it affects spermatogenesis (origin and development of the sperm cells).
Q. What should I avoid while taking Caluran 50 CP Tablet?
Skin sensitivity has been observed in some patients while taking Caluran 50 CP Tablet. Therefore, you should avoid direct sun exposure, sunlamps, and tanning beds. It is advised to use a sunscreen during treatment with Caluran 50 CP Tablet.
Q. Is Caluran 50 CP Tablet a form of chemotherapy?
No, Caluran 50 CP Tablet is not a form of chemotherapy medicine, it is anti-androgen medicine. Androgens such as testosterone are natural male sex hormones. Caluran 50 CP Tablet works by blocking the effect of androgens (testosterone) in order to stop the growth and spread of cancer cells.
Q. Does Caluran 50 CP Tablet cause hair loss?
Yes, Caluran 50 CP Tablet may cause hair loss as it is a common side effect. However, this does not affect everyone. Consult your doctor, if hair loss is worrying you.
Q. What is Caluran 50 CP Tablet prescribed for?
Caluran 50 CP Tablet is used with another medication (gonadotropin-releasing hormone (GnRH) agonists; such as leuprolide or goserelin) to treat metastatic prostate cancer (prostate cancer that has spread to other parts of the body). Other than that, Caluran 50 CP Tablet has been effective in treating hirsutism in patients with polycystic ovarian disease, though this is not an approved use.
Q. When should I take Caluran 50 CP Tablet?
Caluran 50 CP Tablet should be taken at the same time every day either in the morning or in the evening. Take it exactly as directed by your doctor.
Q. Can Caluran 50 CP Tablet cause diarrhea?
Yes, Caluran 50 CP Tablet can cause diarrhea though it is rare. Generally, constipation is more common with this medicine. Consult your doctor if it worries you.
Q. How long do I need to take Caluran 50 CP Tablet?
Caluran 50 CP Tablet tablets should be taken continuously for a minimum of 2 years or until the disease persists. Do not stop taking it without consulting your doctor.
