Manufacturer: Dr Reddy's Laboratories Ltd
Salt Composition : Topotecan(2.5mg)
Cantop 2.5mg Injection is given as an IV infusion into vein by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Topotecan has the same mechanism of action as irinotecan and is believed to exert its cytotoxic effects during the S-phase of DNA synthesis. Topoisomerase I relieves torsional strain in DNA by inducing reversible single strand breaks.
Topotecan (Hycamtin), a semisynthetic water-soluble derivative of camptothecin, is a potent inhibitor of DNA topoisomerase I in vitro and has demonstrated encouraging antitumour activity in a wide variety of tumours, including ovarian cancer and small cell lung cancer.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Cantop
Tiredness
Vomiting
Weakness
Nausea
Abdominal pain
Indigestion
Decreased white blood cell count
Decreased blood cells (red cells, white cells, and platelets)
Diarrhea
Injection site reactions (pain, swelling, redness)
Topotecan Injection is contraindicated in patients who have a history of severe hypersensitivity reactions to topotecan. Reactions have included anaphylactoid reactions [see Adverse Reactions (6.2)]. If you provide additional keywords, you may be able to browse through our database of Scientific Response Documents.
Cantop 2.5mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Consuming alcohol with Cantop 2.5mg Injection does not cause any harmful side effects.
Cantop 2.5mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Use with caution Below 9years: Contraindicated
Topotecan Injection is indicated for the treatment of chemotherapy-sensitive small cell lung cancer (SCLC) after failure of first-line chemotherapy. Chemotherapy-sensitive SCLC is defined as responding to first-line chemotherapy but subsequently progressing at least 60 days after chemotherapy.
infections.
bleeding disorders.
myelosuppression.
renal dysfunction.
diarrhea.
interstitial lung disease.
Kindly do not self administer.
Store below 30°C
If you miss a dose of Cantop 2.5mg Injection, please consult your doctor.
Consult a doctor before taking any medicines.
Cantop 2.5mg Injection helps treat ovarian cancer.
It is given by a drip into a vein (intravenous infusion).
Do not drive or operate machinery as Cantop 2.5mg Injection may cause tiredness, drowsiness or weakness.
Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.
Your doctor may get regular blood tests done to monitor your blood cells during treatment with this medicine.
Inform your doctor immediately if you notice any signs of infection such as fever, sore throat, rash or severe diarrhea.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. How often is Cantop 2.5mg Injection given?
Generally Cantop 2.5mg Injection treatment is for 4 cycles of 21 day each, patient is given Cantop 2.5mg Injection for first 5 days of each cycle.
Q. Does Cantop 2.5mg Injection cause hair loss?
Yes, Cantop 2.5mg Injection may cause temporary hair loss.
Q. Does Cantop 2.5mg Injection cause flare reaction?
Yes, Cantop 2.5mg Injection may cause flare reaction.
Q. How long does Cantop 2.5mg Injection take to work?
Cantop 2.5mg Injection may start its action once the infusion is started, however, the complete effect may be assessed only after completion of 4 cycles.
Q. Is Cantop 2.5mg Injection a vesicant?
Cantop 2.5mg Injection is a vesicant (irritant).
Q. Is Cantop 2.5mg Injection effective?
Yes Cantop 2.5mg Injection is effective if used at prescribed doses for the prescribed duration as advised by your doctor.
Q. What is Cantop 2.5mg Injection chemotherapy?
It is a treatment therapy that includes Cantop 2.5mg Injection with or without combination of other drugs in treatment of cancer (Usually ovarian or lung cancer).
Q. How is Cantop 2.5mg Injection administered?
Cantop 2.5mg Injection is either administered orally as a capsule or as an intravenous Infusion in the arm over a period of 30 min.
