Casodex 50mg Tablet (14'S)

Manufacturer: AstraZeneca

Salt Composition : Bicalutamide(50mg)

Prescription
Prescription Required: Consult the Doctor & Get Your ePrescription

Casodex 50mg Tablet should be taken with or without food, preferably at a fixed time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.



Basic Information

Mechanism Of Action

CASODEX is a non-steroidal antiandrogen. It competitively inhibits the action of androgens by binding to cytosol androgen receptors in the target tissue. Prostatic carcinoma is known to be androgen sensitive and responds to treatment that counteracts the effect of androgen and/or removes the source of androgen.

Pharmacokinets

In terms of pharmacokinetics, bicalutamide is well-absorbed when taken by mouth. However, absorption diminishes at higher dosages. It reaches maximal constant levels after 4 to 12 weeks of therapy. Bicalutamide shows extensive plasma protein binding, mainly to albumin.

Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Casodex

Anemia (low number of red blood cells)

Rash

Abdominal pain

Breast enlargement in male

Breast tenderness

Constipation

Decreased appetite

Decreased libido

Depression

Dizziness

Indigestion

Flatulence

Hot flashes

Increased liver enzymes

Nausea

Sleepiness

Weakness

Weight gain

Contra Indications

Hot flashes, breast swelling/tenderness/pain, nausea, vomiting, constipation, diarrhea, stomach upset, weight changes, headache, trouble sleeping, drowsiness, or dizziness may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

Pregnancy Related Information

Casodex 50mg Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.


Product And Alcohol Interaction

It is not known whether it is safe to consume alcohol with Casodex 50mg Tablet. Please consult your doctor.


Breast Feeding Related Information

Information regarding the use of Casodex 50mg Tablet during breastfeeding is not available. Please consult your doctor.


Children Related Information

Use with caution Below 9years: Contraindicated

Indications

Casodex 50mg Tablet is used in the treatment of cancer of the prostate gland. It may be also used to treat other conditions, as determined by the doctor. It works by blocking the effects of male hormones such as testosterone.

Interactions

Adderall (amphetamine / dextroamphetamine)

Aspir 81 (aspirin)

Aspirin Low Strength (aspirin)

Calcium 600 D (calcium / vitamin d)

CoQ10 (ubiquinone)

Crestor (rosuvastatin)

Eliquis (apixaban)

Fish Oil (omega-3 polyunsaturated fatty acids)

Typical Dosage

Do not chew, crush or break it. Casodex 50mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

Storage Requirements

Store below 30°C


Effects Of Missed Dosage

If you miss a dose of Casodex 50mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.


Effects Of Overdose

Consult a doctor before taking any medicines.

Expert Advice

You have been prescribed Casodex 50mg Tablet for the treatment of prostate cancer.

Take it with or without food, preferably at the same time every day.

It may cause your skin to become light sensitive. Avoid direct exposure to excessive sunlight and use sunscreen when outdoors.

If you are diabetic, monitor your blood glucose regularly while taking Casodex 50mg Tablet.

Your doctor may want you to have regular blood tests to monitor your liver function while you are taking this medicine. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.

Do not stop taking the medication without talking to your doctor first.

How To Use

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Casodex 50mg Tablet may be taken with or without food, but it is better to take it at a fixed time.


FAQs

Q. Can Casodex 50mg Tablet cause infertility?

There is limited data to support that Casodex 50mg Tablet causes infertility. Casodex 50mg Tablet has been shown to affect fertility in animals and therefore it is assumed that it may cause fertility on humans. Some studies have shown that it affects spermatogenesis (origin and development of the sperm cells).

Q. What should I avoid while taking Casodex 50mg Tablet?

Skin sensitivity has been observed in some patients while taking Casodex 50mg Tablet. Therefore, you should avoid direct sun exposure, sunlamps, and tanning beds. It is advised to use a sunscreen during treatment with Casodex 50mg Tablet.

Q. Is Casodex 50mg Tablet a form of chemotherapy?

No, Casodex 50mg Tablet is not a form of chemotherapy medicine, it is anti-androgen medicine. Androgens such as testosterone are natural male sex hormones. Casodex 50mg Tablet works by blocking the effect of androgens (testosterone) in order to stop the growth and spread of cancer cells.

Q. Does Casodex 50mg Tablet cause hair loss?

Yes, Casodex 50mg Tablet may cause hair loss as it is a common side effect. However, this does not affect everyone. Consult your doctor, if hair loss is worrying you.

Q. What is Casodex 50mg Tablet prescribed for?

Casodex 50mg Tablet is used with another medication (gonadotropin-releasing hormone (GnRH) agonists; such as leuprolide or goserelin) to treat metastatic prostate cancer (prostate cancer that has spread to other parts of the body). Other than that, Casodex 50mg Tablet has been effective in treating hirsutism in patients with polycystic ovarian disease, though this is not an approved use.

Q. When should I take Casodex 50mg Tablet?

Casodex 50mg Tablet should be taken at the same time every day either in the morning or in the evening. Take it exactly as directed by your doctor.

Q. Can Casodex 50mg Tablet cause diarrhea?

Yes, Casodex 50mg Tablet can cause diarrhea though it is rare. Generally, constipation is more common with this medicine. Consult your doctor if it worries you.

Q. How long do I need to take Casodex 50mg Tablet?

Casodex 50mg Tablet tablets should be taken continuously for a minimum of 2 years or until the disease persists. Do not stop taking it without consulting your doctor.