Manufacturer: Dr Reddy's Laboratories Ltd
Salt Composition : Cabazitaxel(60mg/ml)
Cazat Injection is given under the supervision of a healthcare professional and should not be self-administered. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. You should avoid drinking alcohol as it may increase your risk of liver damage.
Cabazitaxel is a novel second-generation, semisynthetic microtubule inhibitor (specifically, a taxane derivative) that induces cell death by microtubule stabilization. Its mechanism of action is similar to that of paclitaxel and docetaxel.
Cabazitaxel is excreted mainly into feces (76% of the administered dose) as approximately 20 metabolites, with a low urinary excretion (3.7% of the administered dose with 2.3% excreted as unchanged drug).
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Cazat
Vomiting
Back pain
Weakness
Low blood platelets
Hair loss
Abdominal pain
Loss of appetite
Anemia (low number of red blood cells)
Diarrhea
Stomatitis (Inflammation of the mouth)
Blood in urine
Constipation
Cough
Taste change
Breathing problems
Decreased white blood cell count (neutrophils)
Nausea
Vomiting.
Back pain.
Weakness.
Low blood platelets.
Hair loss.
Abdominal pain.
Loss of appetite.
Anemia (low number of red blood cells)
Cazat Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
It is unsafe to consume alcohol with Cazat Injection.
Cazat Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Use with caution Below 9years: Contraindicated
Cabazitaxel injection is used along with prednisone to treat prostate cancer (cancer of a male reproductive organ) that has already been treated with other medications. Cabazitaxel injection is in a class of medications called microtubule inhibitors. It works by slowing or stopping the growth of cancer cells.
Key Points. In the first-line treatment of metastatic castration-resistant prostate cancer, there was no difference in overall survival observed for cabazitaxel vs docetaxel regimens. However, toxicity profiles differed, with lower-dose cabazitaxel being associated with less toxicity overall.
Kindly do not self administer.
Store below 30°C
If you miss a dose of Cazat Injection, please consult your doctor.
Consult a doctor before taking any medicines.
Cazat Injection is given as an infusion into a vein (IV infusion) under the supervision of a doctor only.
Do not skip any dose and complete the course as suggested by your doctor.
Use an effective method of birth control to avoid pregnancy while taking this medication.
You may need to have blood tests to monitor your blood cells, platelets count, liver function and kidney function during treatment.
Inform your doctor immediately if you notice unusual bruising or bleeding or if you have dark, tarry, or bloody stools and sore throat.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. Is Cazat Injection a vesicant or chemotherapeutic drug?
Cazat Injection is a chemotherapeutic drug (drug used for the management of cancer). It is, however, not a vesicant (drug which causes severe blisters on the skin).
