Manufacturer: Parenteral Drugs India Ltd
Salt Composition : Cefotaxime(500mg), Sulbactam(250mg)
Vial of 1 Injection
(Inclusive of all taxes)
Cefnimax S 500 mg/250 mg Injection should only be administered under the supervision of a healthcare professional. Do not miss any scheduled appointments for taking this medicine. The course of the treatment must be completed even if you feel better. Sudden discontinuation of the treatment may affect the potency of the medicine.
Cefotaxime sodium, a parenteral cephalosporin antibiotic, exerts its bactericidal action through inhibition of bacterial cell wall synthesis. Chemical structure modifications have enabled this compound to be resistant to the action of Richmond I, III, IV, and V beta-lactamase enzymes.
Sulbactam is an irreversible inhibitor of β-lactamase; by binding and inhibiting β-lactamase produced by bacterial cells, sulbactam is thereby able to prevent it from reducing antibiotic activity.
Ceftriaxone is primarily eliminated in the urine (33-67%). The remainder is eliminated through secretion in the bile and removed from the body via the feces. The elimination half-life of ceftriaxone is 5.8-8.7 hours. The half-life of ceftriaxone in the middle ear fluid has been estimated to be 25 hours.
The rationale behind addition of sulbactam and disodium edetate (EDTA) with ceftriaxone was to provide multiple mechanisms of antibacterial actions. Sulbactam, a BLI can be effective against various beta lactamase producing microbes.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Cefnimax S
Injection site reactions (pain, swelling, redness)
Diarrhea
Allergic reaction
Nausea
Vomiting
diarrhea from an infection with Clostridium difficile bacteria.
decreased kidney function.
inflammation of the liver with stoppage of bile flow.
inflammation of the large intestine.
severe renal impairment.
Cefnimax S 500 mg/250 mg Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Caution is advised when consuming alcohol with Cefnimax S 500 mg/250 mg Injection. Please consult your doctor.
Cefnimax S 500 mg/250 mg Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
CEFOTAXIME+SULBACTAM is used to treat bacterial infections. It contains Cefotaxime and Sulbactam. Cefotaxime reduces the infection by inhibiting bacterial growth. It disrupts the formation of the cell wall (outer layer), which is essential for bacteria's survival.
Drug-Drug Interactions: CEFOTAXIME+SULBACTAM may interact with penicillin antibiotics (mezlocillin and azlocillin), aminoglycoside antibiotics (streptomycin, neomycin, and gentamicin), diuretic or water pill (furosemide), and medicine used to treat gout (probenecid).
Kindly do not self administer.
Store below 30°C
If you miss a dose of Cefnimax S 500 mg/250 mg Injection, please consult your doctor.
Consult a doctor before taking any medicines.
You have been prescribed this combination medicine to treat bacterial infections even if they have developed resistance.
Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
Diarrhea may occur as a side effect. Taking probiotics along with Cefnimax S 500 mg/250 mg Injection may help. Talk to your doctor if you notice bloody stools or develop abdominal cramps.
Stop taking Cefnimax S 500 mg/250 mg Injection and inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking it.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. Can the use of Cefnimax S 500 mg/250 mg Injection cause diarrhea?
Yes, the use of Cefnimax S 500 mg/250 mg Injection can cause diarrhea. It is an antibiotic which kills the harmful bacteria. However, it also affects the helpful bacteria in your stomach or intestine and causes diarrhea. If you are experiencing severe diarrhea, talk to your doctor about it.
Q. How long does Cefnimax S 500 mg/250 mg Injection takes to work?
Usually, Cefnimax S 500 mg/250 mg Injection starts working soon after taking it. However, it may take some days to kill all the harmful bacteria and make you feel better.
Q. What if I don't get better after using Cefnimax S 500 mg/250 mg Injection?
Inform your doctor if you don't feel better after finishing the full course of treatment. Also, inform him if your symptoms are getting worse while using this medicine.
