Cefokem XP 2000 mg / 1000 mg (Injection)

Prescription
Prescription Required: Consult the Doctor & Get Your ePrescription

Cefokem XP 2000 mg/1000 mg Injection should only be administered under the supervision of a healthcare professional. Do not miss any scheduled appointments for taking this medicine. The course of the treatment must be completed even if you feel better. Sudden discontinuation of the treatment may affect the potency of the medicine.



Basic Information

Mechanism Of Action

Cefokem XP 2000 mg/1000 mg Injection contains two different medicines, Cefoperazone and Sulbactum, that work together to kill the bacteria that cause infections. Cefoperazone works by stopping the growth of bacteria. Sulbactam reduces resistance and enhances the activity of Cefoperazone against bacteria

Pharmacokinets

Cefoperazone was 90% bound to serum proteins. The apparent volume of distribution was 10 to 13L. The half-life of the drug varied from 1.6 to 2.4 hours; serum clearance was between 75 and 96 ml/min. Urinary excretion was rapid, but only 15 to 36% of the cefoperazone dose was recovered in the urine

Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Cefokem XP

Diarrhea

Abnormal liver function tests

Allergic reaction

Anemia (low number of red blood cells)


Contra Indications

diarrhea from an infection with Clostridium difficile bacteria.

low vitamin K levels.

a decrease in the blood clotting protein prothrombin.

increased risk of bleeding due to clotting disorder.

alcohol intoxication.

inflammation of the large intestine.

liver problems.

The use of UNASYN is contraindicated in individuals with a history of serious hypersensitivity reactions (e.g., anaphylaxis or Stevens-Johnson syndrome) to ampicillin, sulbactam or to other beta-lactam antibacterial drugs (e.g., penicillins and cephalosporins).

Pregnancy Related Information

Cefokem XP 2000 mg/1000 mg Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.


Product And Alcohol Interaction

Consuming alcohol while taking Cefokem XP 2000 mg/1000 mg Injection may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).


Breast Feeding Related Information

Cefokem XP 2000 mg/1000 mg Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.


Indications

Respiratory tract infections (upper and lower)

Urinary tract infections (upper and lower)

Peritonitis, cholecystitis, cholangitis, and other intra-abdominal infections.

Septicaemia.

Meningitis.

Skin and soft tissue infections.

Bone and joint infections

Interactions

colitis.

hypoprothrombinemia.

renal/liver disease.

sodium.

dialysis.

disulfiram-like reaction.

liver disease.

Typical Dosage

Kindly do not self administer.


Storage Requirements

Store below 30°C


Effects Of Missed Dosage

If you miss a dose of Cefokem XP 2000 mg/1000 mg Injection, please consult your doctor.


Effects Of Overdose

If you miss a dose of Cefokem XP 2000 mg/1000 mg Injection, please consult your doctor.


Expert Advice

You have been prescribed this combination medicine to treat bacterial infections even if they have developed resistance. 

Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.

Diarrhea may occur as a side effect. Taking probiotics along with Cefokem XP 2000 mg/1000 mg Injection may help. Talk to your doctor if you notice bloody stools or develop abdominal cramps.

Stop taking Cefokem XP 2000 mg/1000 mg Injection and inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking it

How To Use

Your doctor or nurse will give you this medicine. Kindly do not self administer.


FAQs

Q. What is Cefokem XP 2000 mg/1000 mg Injection?

Cefokem XP 2000 mg/1000 mg Injection is a combination of two medicines: Cefoperazone and Sulbactam. Cefoperazone is an antibiotic which works by preventing the formation of the bacterial protective covering which is essential for the survival of bacteria. Sulbactam is a beta-lactamase inhibitor which reduces resistance and enhances the activity of Cefoperazone against bacteria.

Q. How long does Cefokem XP 2000 mg/1000 mg Injection takes to work?

Usually, Cefokem XP 2000 mg/1000 mg Injection starts working soon after taking it. However, it may take some days to kill all the harmful bacteria and make you feel better.

Q. What if I don't get better after using Cefokem XP 2000 mg/1000 mg Injection?

Inform your doctor if you don't feel better after finishing the full course of treatment. Also, inform him if your symptoms are getting worse while using this medicine.