Manufacturer: Macleods Pharmaceuticals Pvt Ltd
Salt Composition : Ceftriaxone(250mg), Sulbactam(125mg)
Vial of 5ml Injection
(Inclusive of all taxes)
Cefrine Plus 250 mg/125 mg Injection should only be administered under the supervision of a healthcare professional. Do not miss any scheduled appointments for taking this medicine. The course of the treatment must be completed even if you feel better. Sudden discontinuation of the treatment may affect the potency of the medicine.
Ceftriaxone is a cephalosporin antibiotic. It has bactericidal action (kills bacteria). It works by preventing the formation of the cell wall (the outer protective layer of bacteria, which is essential for its survival) by preventing protein synthesis. Sulbactam inhibits the action of beta-lactamase
The mean peaks of ceftriaxone and sulbactam concentrations in plasma were 152.06+/-6.65 microg/ml and 21.32+/-1.80 microg/ml, respectively and plasma half-lives for ceftriaxone and sulbactam were 5.2+/-0.35 hr and 0.94+/-0.038 hr, respectively
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Cefrine Plus
Diarrhea
Increased liver enzymes
Allergic reaction
Rash
diarrhea from an infection with Clostridium difficile bacteria.
a type of blood disorder where the red blood cells burst called hemolytic anemia.
liver problems.
disease of the gallbladder.
severe renal impairment.
yellowing of the skin in a newborn child
Cefrine Plus 250 mg/125 mg Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Consuming alcohol with Cefrine Plus 250 mg/125 mg Injection does not cause any harmful side effects.
Cefrine Plus 250 mg/125 mg Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Ceftriaxone+Sulbactam is used in the treatment of bacterial infections. Ceftriaxone + Sulbactam is a combination of two medicines: Ceftriaxone and Sulbactam. Ceftriaxone is an antibiotic. It works by preventing the formation of the bacterial protective covering which is essential for the survival of bacteria
Drug-Drug Interactions: CEFTRIAXONE+SULBACTAM may interact with vaccines (cholera vaccine) estrogens (ethinyl estradiol), penicillin antibiotics (mezlocillin and azlocillin), aminoglycoside antibiotics (amikacin, streptomycin, neomycin and gentamicin), immuno-suppressant(cyclosporine) and medicine used to treat gout
Kindly do not self administer.
Store below 30°C
If you miss a dose of Cefrine Plus 250 mg/125 mg Injection, please consult your doctor.
Consult a doctor before taking any medicines.
You have been prescribed this combination medicine to treat bacterial infections even if they have developed resistance.
Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
Diarrhea may occur as a side effect. Taking probiotics along with Cefrine Plus 250 mg/125 mg Injection may help. Talk to your doctor if you notice bloody stools or develop abdominal cramps.
Stop taking Cefrine Plus 250 mg/125 mg Injection and inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking it.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. Can the use of Cefrine Plus 250 mg/125 mg Injection cause allergic reaction?
Yes, Cefrine Plus 250 mg/125 mg Injection can cause an allergic reaction and is considered to be harmful for patients with known allergy to a group of antibiotic called cephalosporins. Seek emergency medical help if you have any sign of an allergic reaction like hives; difficulty in breathing; swelling of your face, lips, tongue, or throat.
Q. Can the use of Cefrine Plus 250 mg/125 mg Injection cause diarrhea?
Yes, the use of Cefrine Plus 250 mg/125 mg Injection can cause diarrhea. It is an antibiotic which kills the harmful bacteria. However, it also affects the helpful bacteria in your stomach or intestine and causes diarrhea. If you are experiencing severe diarrhea, talk to your doctor about it.
Q. How long does Cefrine Plus 250 mg/125 mg Injection takes to work?
Usually, Cefrine Plus 250 mg/125 mg Injection starts working soon after taking it. However, it may take some days to kill all the harmful bacteria and make you feel better.
Q. What if I don't get better after using Cefrine Plus 250 mg/125 mg Injection?
Inform your doctor if you don't feel better after finishing the full course of treatment. Also, inform him if your symptoms are getting worse while using this medicine.
Q. Can I stop taking Cefrine Plus 250 mg/125 mg Injection when I feel better?
No, do not stop taking Cefrine Plus 250 mg/125 mg Injection and complete the full course of treatment even if you feel better. Your symptoms may improve before the infection is completely cured.
