Manufacturer: Biocon
Salt Composition : Cefoperazone(1000mg), Tazobactum(125mg)
Cegava TZ 1000 mg/125 mg Injection should only be administered under the supervision of a healthcare professional. Do not miss any scheduled appointments for taking this medicine. The course of the treatment must be completed even if you feel better. Sudden discontinuation of the treatment may affect the potency of the medicine.
Cefoperazone is bactericidal in action. The antibacterial activity of the drug results from inhibition of nucleopeptide synthesis in the bacterial cell wall. Tazobactam has little, clinically relevant activity against bacteria due to its reduced affinity to penicillin binding proteins.
Cefoperazone was 90% bound to serum proteins. The apparent volume of distribution was 10 to 13L. The half-life of the drug varied from 1.6 to 2.4 hours; serum clearance was between 75 and 96 ml/min. Urinary excretion was rapid, but only 15 to 36% of the cefoperazone dose was recovered in the urine.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Cegava TZ
Diarrhea
Abnormal liver function tests
Allergic reaction
Anemia (low number of red blood cells)
Cefoperazone and tazobactam are contraindicated in patients with a known allergy to penicillins, tazobactam, cefoperazone, or any of the cephalosporins. Use of cephalosporin should be avoided in patients who have had an immediate type I (anaphylactic) reaction to penicillins.
Cegava TZ 1000 mg/125 mg Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Consuming alcohol while taking Cegava TZ 1000 mg/125 mg Injection may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).
Cegava TZ 1000 mg/125 mg Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Cefoperazone and tazobactam injection is indicated for the treatment of gynecological infections, urinary tract infections, and post-operative infections.
colitis.
hypoprothrombinemia.
renal/liver disease.
sodium.
dialysis.
disulfiram-like reaction.
liver disease.
coagulation abnormalities.
renal dysfunction.
hemodialysis.
cystic fibrosis.
seizures.
sodium/potassium.
Kindly do not self administer.
Store below 30°C
If you miss a dose of Cegava TZ 1000 mg/125 mg Injection, please consult your doctor.
Consult a doctor before taking any medicines
You have been prescribed this combination medicine to treat bacterial infections even if they have developed resistance.
Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
Diarrhea may occur as a side effect. Taking probiotics along with Cegava TZ 1000 mg/125 mg Injection may help. Talk to your doctor if you notice bloody stools or develop abdominal cramps.
Stop taking Cegava TZ 1000 mg/125 mg Injection and inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking it.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. Can the use of Cegava TZ 1000 mg/125 mg Injection cause diarrhea?
Yes, the use of Cegava TZ 1000 mg/125 mg Injection can cause diarrhea. It is an antibiotic which kills the harmful bacteria. However, it also affects the helpful bacteria in your stomach or intestine and causes diarrhea. If you are experiencing severe diarrhea, talk to your doctor about it.
Q. How long does Cegava TZ 1000 mg/125 mg Injection takes to work?
Usually, Cegava TZ 1000 mg/125 mg Injection starts working soon after taking it. However, it may take some days to kill all the harmful bacteria and make you feel better.
Q. What if I don't get better after using Cegava TZ 1000 mg/125 mg Injection?
Inform your doctor if you don't feel better after finishing the full course of treatment. Also, inform him if your symptoms are getting worse while using this medicine.
Q. Can I stop taking Cegava TZ 1000 mg/125 mg Injection when I feel better?
No, do not stop taking Cegava TZ 1000 mg/125 mg Injection and complete the full course of treatment even if you feel better. Your symptoms may improve before the infection is completely cured.
