Celcarb 450mg (Injection)

Manufacturer: Celon Laboratories Ltd

Salt Composition : Carboplatin(450mg)

Prescription
Prescription Required: Consult the Doctor & Get Your ePrescription

Celcarb 450mg Injection is given as an injection into veins under the supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.



Basic Information

Mechanism Of Action

Carboplatin undergoes activation inside cells and forms reactive platinum complexes that cause the intra- and inter-strand cross-linkage of DNA molecules within the cell. This modifies the DNA structure and inhibits DNA synthesis. This may affect a cell in all the phases of its cycle.


Pharmacokinets

Carboplatin did not bind to plasma protein in vitro but did degrade (t1/2-26 hours) to yield a reactive intermediate that bound rapidly and irreversibly to protein. The long terminal elimination half-life of plasma platinum was associated with irreversible binding of a platinum metabonate to plasma protein.


Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Celcarb

Nausea

Vomiting

Anemia (low number of red blood cells)

Fatigue

Low blood platelets

Increased liver enzymes

Decreased white blood cell count (neutrophils)

Stomatitis (Inflammation of the mouth)

Peripheral neuropathy (tingling and numbness of feet and hand)

Diarrhea

Contra Indications

a bad infection.

decreased function of bone marrow.

anemia.

an increased risk of bleeding.

decreased blood platelets.

low levels of white blood cells.

low levels of a type of white blood cell called neutrophils.

Pregnancy Related Information

Celcarb 450mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.


Product And Alcohol Interaction

It is not known whether it is safe to consume alcohol with Celcarb 450mg Injection. Please consult your doctor.


Breast Feeding Related Information

Celcarb 450mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.


Indications

Carboplatin injection is indicated for the palliative treatment of patients with ovarian carcinoma recurrent after prior chemotherapy, including patients who have been previously treated with cisplatin.


Interactions

adenovirus types 4 and 7 live, oral.

amphotericin B deoxycholate.

bacitracin.

cidofovir.

influenza virus vaccine trivalent, adjuvanted.

palifermin.

tofacitinib.

Typical Dosage

Kindly do not self administer.


Storage Requirements

Store below 30°C


Effects Of Missed Dosage

If you miss a dose of Celcarb 450mg Injection, please consult your doctor.


Effects Of Overdose

Consult a doctor before taking any medicines.


Expert Advice

It is given as an injection into the veins under the supervision of a doctor.


How To Use

Your doctor or nurse will give you this medicine. Kindly do not self administer.


FAQs

Q. Is Celcarb 450mg Injection cell cycle specific?

No, Celcarb 450mg Injection is not a cell cycle specific anticancer medication

Q. Is Celcarb 450mg Injection FDA approved?

Yes Celcarb 450mg Injection is an FDA approved drug

Q. Is it a platinum based drug?

Yes carboplatin is a platinum based drug and is effectively used in combination with other drug

Q. Does Celcarb 450mg Injection cause neuropathy/ hearing loss/ hair loss/ weight gain/ constipation/ leukemia?

Yes Celcarb 450mg Injection is known to cause side effects like neuropathy, hearing loss, hair loss, weight gain, and constipation. Please inform your doctor about any side-effect that you may observe on taking this drug. Infertility while on therapy may be caused as a side effect of this drug but it may be reverse after stopping the therapy. Yes Celcarb 450mg Injection may cause leukemia if it is used for a long duration.

Q. Is Celcarb 450mg Injection a generic?

Yes, Celcarb 450mg Injection is a generic platinum-based compound

Q. Is Celcarb 450mg Injection vesicant/cardio-toxic/ anthracycline?

No Celcarb 450mg Injection is not cardio-toxic/ anthracycline/vesicant

Q. Is Celcarb 450mg Injection used for breast cancer?

It is used to treat advanced stage breast cancer

Q. Is Celcarb 450mg Injection available in pill form?

No Celcarb 450mg Injection is not available in pill form