Manufacturer: Celon Laboratories Ltd
Salt Composition : Oxaliplatin(100mg)
Celdach 100mg Injection is given as an injection into vein by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
After activation, oxaliplatin binds preferentially to the guanine and cytosine moieties of DNA, leading to cross-linking of DNA, thus inhibiting DNA synthesis and transcription. Cytotoxicity is cell-cycle nonspecific. Bioavailability is complete following intravenous administration.
The pharmacokinetics of oxaliplatin are described by a 3-compartment model. The drug rapidly crosses the cellular membrane as a result of its lipophilicity. Hence, at the end of a 2-hour infusion, approximately 40% of the blood platinum is found in erythrocytes.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Celdach
Nausea
Fatigue
Anemia (low number of red blood cells)
Vomiting
Diarrhea
Decreased white blood cell count (neutrophils)
Low blood platelets
Increased liver enzymes
Peripheral neuropathy (tingling and numbness of feet and hand)
Stomatitis (Inflammation of the mouth)
Platinum hypersensitivity anaphylaxis
Posterior reversible encephalopathy syndrome
Grade 3 or 4 peripheral sensory neuropathy
Severe renal impairment
Chronic lung disease
Rhabdomyolysis
Sepsis
Pregnant or intending to get pregnant
Celdach 100mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
It is not known whether it is safe to consume alcohol with Celdach 100mg Injection. Please consult your doctor.
Celdach 100mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
adjuvant treatment of stage III colon cancer in patients who have undergone complete resection of the primary tumor.
treatment of advanced colorectal cancer.
arrhythmias.
pulmonary toxicity.
neurologic toxicity.
neutropenia.
renal impairment.
rhabdomyolysis.
thrombocytopenia.
Kindly do not self administer.
Store below 30°C
If you miss a dose of Celdach 100mg Injection, please consult your doctor.
Consult a doctor before taking any medicines.
Celdach 100mg Injection is given as an injection into veins under the supervision of a doctor.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
