Manufacturer: Cipla Ltd
Salt Composition : Mycophenolate mofetil(500mg)
The amount of Cellmune 500mg Tablet you take and how often you take it depends on the type of transplant you have. Follow your doctor’s instructions on this. You should take it on an empty stomach, at least 1 hour before or 2 hours after a meal. Swallow it as a whole, do not crush, chew, or break it. Take the medicine regularly to get maximum benefit and keep taking it even when you feel well. The treatment will continue for as long as you need it to prevent rejection.
Mycophenolate mofetil (MMF, CellCept) is a prodrug of mycophenolic acid (MPA), an inhibitor of inosine-5'-monophosphate dehydrogenase. MPA depletes guanosine nucleotides preferentially in T and B lymphocytes and inhibits their proliferation, thereby suppressing cell-mediated immune responses and antibody formation.
Mycophenolate mofetil is rapidly absorbed in the small intestine. The maximum concentration of its active metabolite, MPA, is attained 60 to 90 minutes following an oral dose. The average bioavailability of orally administered mycophenolate mofetil in a pharmacokinetic study of 12 healthy patients was 94%.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Cellmune
Nausea
Vomiting
Diarrhea
Abdominal pain
Headache
High blood pressure
Decreased white blood cell count (neutrophils)
shingles in patients without a normal immune system.
a herpes simplex infection.
an unusual viral infection called cytomegalovirus infection.
opportunistic fungal infection.
a bad infection.
cancer or malignancy.
decreased function of bone marrow.
Cellmune 500mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Consuming alcohol with Cellmune 500mg Tablet does not cause any harmful side effects.
Cellmune 500mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Mycophenolate mofetil is indicated for the prophylaxis of organ rejection in patients undergoing allogeneic renal, hepatic, or cardiac transplants. It should be used with cyclosporine and corticosteroids.
neutropenia.
GI hemorrhage.
hepatic dysfunction.
renal dysfunction.
HGPRT deficiency.
vaccination.
Do not chew, crush or break it. Cellmune 500mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
Consult a doctor before taking any medicines.
Your doctor has prescribed Cellmune 500mg Tablet to stop your body from rejecting a transplanted organ (e.g. kidney, heart or liver).
It may take 6 to 12 weeks for Cellmune 500mg Tablet to start working. Keep taking it as prescribed.
It may cause birth defects so birth control is required in females with reproductive potential.
It makes you more susceptible to getting infections. Avoid contact with people who have an infection. Consult your doctor immediately if you develop a sore throat, high temperature, any other signs of infections.
Protect yourself from direct sunlight by wearing protective clothing and applying a sunscreen with a high sun protection factor (SPF).
Take it with food to minimize possible side effects like nausea and stomach pain.
Your doctor may get regular blood tests done to monitor the levels of blood cells in your blood. Inform your doctor if you experience symptoms such as unexplained bruising or bleeding, sore throat, mouth ulcers, or fever.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Cellmune 500mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Q. Can Cellmune 500mg Tablet cause cancer?
Cellmune 500mg Tablet may increase your chances of certain cancers like skin cancer and lymphoma (cancer of the lymph system). When outside, avoid unnecessary or prolonged exposure to sunlight, wear protective clothing, and apply sunscreen. Call your doctor if you experience a new skin sore or bump, a change in the size or color of a mole, a brown or black skin lesion (sore) with uneven edges or a sore whose one part does not look like the other, skin changes, sores that do not heal. Also, inform the doctor if you experience unexplained fever, tiredness that does not go away, weight loss, or pain or swelling in the neck, groin, or armpits.
Q. Why has my doctor given me Cellmune 500mg Tablet after I have had a kidney transplant?
Cellmune 500mg Tablet is an immunosuppressant. Cellmune 500mg Tablet has been prescribed to you to help your body accept the donor's kidney. It does so by working on the cells of your immune system, which fight with any foreign substance and reject its presence. This helps in making the transplanted organ more acceptable to your body.
Q. How long does Cellmune 500mg Tablet take to start working?
Cellmune 500mg Tablet does not start working immediately and may take about 8 to 12 weeks before you see any benefits. To ensure that your condition does not reappear, you may have to keep taking the medicine for several years.
Q. Is Cellmune 500mg Tablet a steroid or chemotherapy medicine? Can it cause hair loss?
Cellmune 500mg Tablet is neither a steroid nor a chemotherapy medicine. It is an immunosuppressant which means that it acts on your immune system to suppress or weaken it so that your body does not reject the donated organ of another person. Hair loss is a common side effect of Cellmune 500mg Tablet.
Q. Do I need any special tests while taking Cellmune 500mg Tablet?
Since Cellmune 500mg Tablet can affect blood count and affect the kidneys and liver, your doctor will ask you to have a blood test before you start the treatment. Once the treatment starts, your doctor will suggest you take regular blood tests to check for any changes in the blood. These blood tests will help monitor your response to the medicine and the development of any side effects.
Q. My doctor has asked me to stay away from a person who has chickenpox or shingles. Why?
Cellmune 500mg Tablet is an immunosuppressant, which means that it decreases the activity of the immune system. Since your immune system is already weak, if you come in contact with a patient of chickenpox or shingles, you may develop it too. This is the reason that your doctor has advised you to be cautious. Therefore, follow your doctor’s advice and contact your doctor immediately if you get chickenpox or shingles as you may require special treatment.
Q. What precautions should a female follow while taking Cellmune 500mg Tablet?
Do not take Cellmune 500mg Tablet if you are pregnant or are planning a pregnancy. There is a high risk of miscarriage (loss of the pregnancy) during the first 3 months of pregnancy. It may even cause birth defects (problems that are present at birth) in the newborn. Therefore, it is advised that you should use two acceptable forms of birth control together for 4 weeks before you start taking Cellmune 500mg Tablet, during the treatment, and for 6 weeks after you stop taking Cellmune 500mg Tablet. It is important to use a second form of birth control along with birth control pills as Cellmune 500mg Tablet may decrease the effectiveness of birth control pills. Your doctor will suggest the two birth control methods that\ suit you the best.
Q. What precautions should a male follow while taking Cellmune 500mg Tablet?
It is recommended that either the man or her partner should use reliable contraception during treatment and for 90 days after the treatment. Men should not donate semen during the therapy or for 90 days following discontinuation of Cellmune 500mg Tablet.
