Manufacturer: Celon Laboratories Ltd
Salt Composition : Letrozole(2.5mg)
Celofem 2.5mg Tablet is also helpful in the treatment of infertility. It can be taken with or without food, but take it at about the same time to get the most benefit. The dose and frequency depend on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed.
Letrozole is an aromatase inhibitor used in the treatment of breast cancer. Aromatase inhibitors work by inhibiting the action of the enzyme aromatase, which converts androgens into estrogens by a process called aromatization.
It has a large apparent volume of distribution at steady state (1.87 l/kg [range, 1.47–3.24]), and approximately 60% is bound to plasma proteins, mainly to albumin (55%). The terminal half-life (T1/2) of letrozole is 42 h
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Celofem
Fatigue
Hypercholesterolemia (high cholesterol)
Increased sweating
Hot flashes
high cholesterol.
a disorder of the blood vessels of the brain.
obstruction of a blood vessel by a blood clot.
hardening of the liver.
severe liver disease.
osteoporosis, a condition of weak bones.
decreased calcification or density of bone.
high amount of bilirubin in the blood.
Celofem 2.5mg Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Consuming alcohol with Celofem 2.5mg Tablet does not cause any harmful side effects.
Celofem 2.5mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Letrozole is indicated to treat postmenopausal women with hormone receptor (HR) positive early breast cancer, postmenopausal women with early breast cancer who have periviously been treated with tamoxifen, and postmenopausal women with HR+ or unknown advanced breast cancer.
Letrozole has no known severe interactions with other drugs.
Serious interactions of letrozole include: ethinylestradiol. tamoxifen.
Moderate interactions of letrozole include: cholera vaccine. eluxadoline.
Letrozole has no known minor interactions with other drugs.
Do not chew, crush or break it. Celofem 2.5mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Celofem 2.5mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
You have been prescribed Celofem 2.5mg Tablet for the treatment of breast cancer or infertility due to anovulation.
It can be taken with or without food.
Do not drive or do anything requiring concentration until you know how Celofem 2.5mg Tablet affects you.
It may cause increased sweating and hot flushes. Try to keep cool by wearing light and airy clothes.
Your doctor may monitor your cholesterol level and bone mineral density (BMD) regularly as Celofem 2.5mg Tablet can alter their levels.
Do not take Celofem 2.5mg Tablet if you are pregnant or breastfeeding
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Celofem 2.5mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Q. Why have I been prescribed Celofem 2.5mg Tablet?
Celofem 2.5mg Tablet is an aromatase inhibitor. It is generally prescribed to treat breast cancer in women who no longer have periods, either due to menopause or after surgery or chemotherapy. It is also used to treat infertility caused due to anovulation (during menstrual cycle egg cell from ovaries is not released).
Q. How does Celofem 2.5mg Tablet work?
Celofem 2.5mg Tablet is also known as an anti-estrogen drug. It is called so because it acts by reducing the production of estrogen in your body by blocking the enzyme aromatase, which is responsible for the production of estrogen. Estrogen stimulates the production of certain types of breast cancer in your body. These cancers are called "estrogen-dependent cancers". Reducing the production of estrogen may prevent cancer from growing.
Q. For how long should I take Celofem 2.5mg Tablet?
If the breast tumor is in the advanced stage or has spread to other parts of the body, it is recommended that you continue taking Celofem 2.5mg Tablet till the tumor shows progression. In cases where Celofem 2.5mg Tablet is given after tamoxifen (another anti-estrogen used for breast cancer) or surgery, it should be given for 5 years or until the tumor comes back, whichever is first. It can also be given as a sequential treatment; 2 years of Celofem 2.5mg Tablet followed by 3 years of tamoxifen.
Q. If I am taking irbesartan to control my blood pressure, can I take Celofem 2.5mg Tablet?
Yes, you can take irbesartan and Celofem 2.5mg Tablet together. However, be careful and keep a regular check on your blood pressure since Celofem 2.5mg Tablet may increase your blood pressure. Consult your doctor in case you have problems controlling your blood pressure.
Q. Does Celofem 2.5mg Tablet affect vision?
Although it is very uncommon, Celofem 2.5mg Tablet may cause a cataract. So, if you experience blurred vision or eye irritation, consult your doctor immediately.
Q. My friend who is taking Celofem 2.5mg Tablet often sweats a lot. Is it because of Celofem 2.5mg Tablet?
This could be a sign of hot flushes which is a very common side effect of Celofem 2.5mg Tablet. It happens due to decreased estrogen levels. The frequency of hot flushes reduces once your body adjusts to Celofem 2.5mg Tablet. However, in some people, the flushes and sweats may continue during the treatment and stop a few months after the treatment finishes. You can consult your doctor who will provide you a remedy if it is very bothersome.
Q. What are the serious side effects of Celofem 2.5mg Tablet?
The serious side effects do not occur in everyone and very few people experience them. The serious side effects of Celofem 2.5mg Tablet include stroke, angina, heart attack, blood clotting, cataract, osteoporosis, and severe skin reactions.
