Manufacturer: Biocon
Salt Composition : Cefepime(1000mg), Tazobactum(125mg)
Celrim TZ 1000 mg/125 mg Injection should only be administered under the supervision of a healthcare professional. Do not miss any scheduled appointments for taking this medicine. The course of the medicine should be completed even if you feel better.
Cefepime-tazobactam can be used for treatment of ESBL producing Enterobacteriaceae. This will help to reduce the usage of carbapenems in ESBL positive Enterobacteriaceae strains and prevent development of carbapenem resistance. This combination has shown good in-vivo response in many patients who were treated.
For cefepime, the mean (plus or minus standard deviation [SD]) elimination half-life was 3.33 ± 0.74 h and the peak concentration in serum was 70.5 ± 20.8 mg/liter. Mean (plus or minus SD) total body clearance was 75.5 ± 12.9 ml/min. Renal clearance accounted for 80.3% ± 10.6% of drug removal.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Celrim TZ-
Diarrhea
Injection site reaction
Injection site pain
Injection site inflammation
Allergic reaction
Rash
diarrhea from an infection with Clostridium difficile bacteria.
a decrease in the blood clotting protein prothrombin.
an increased risk of bleeding.
myoclonus, quick and involuntary muscle jerks.
inflammation of the large intestine.
mild to moderate kidney impairment.
seizures.
low amount of potassium in the blood.
increased risk of bleeding due to clotting disorder.
seizures.
a significant drop in a certain type of white blood cell called a neutrophil.
Celrim TZ 1000 mg/125 mg Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Caution is advised when consuming alcohol with Celrim TZ 1000 mg/125 mg Injection. Please consult your doctor.
Celrim TZ 1000 mg/125 mg Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Cefepime/tazobactam (FORPAR XP) is a BL/BLI and is indicated for uncomplicated and complicated urinary tract infections, uncomplicated skin and skin structure infections, complicated intra-abdominal infections, LRTIs, including pneumonia and bronchitis, septicaemia and for empiric treatment in febrile neutropenic
Drug-Drug Interactions: CEFEPIME+TAZOBACTAM may interact with aminoglycoside antibiotics (streptomycin, neomycin, and gentamicin) as it may cause severe nephrotoxicity (damage to the kidney). It may also interact with a medicine used to treat gout
Kindly do not self-administer.
Store below 30°C
If you miss a dose of Celrim TZ 1000 mg/125 mg Injection, please consult your doctor.
Consult a doctor before taking any medicines.
You have been prescribed this combination medicine to treat bacterial infections, even if they have developed resistance.
Finish the full course of treatment even if you feel better. Stopping it early may make the infection to come back and harder to treat.
Talk to your doctor if you notice bloody stools or develop abdominal cramps.
Inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking it.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. How long does Celrim TZ 1000 mg/125 mg Injection takes to work?
Usually, Celrim TZ 1000 mg/125 mg Injection starts working soon after taking it. However, it may take some days to kill all the harmful bacteria and make you feel better.
Q. What if I don't get better after using Celrim TZ 1000 mg/125 mg Injection?
Inform your doctor if you don't feel better after finishing the full course of treatment. Also, inform him if your symptoms are getting worse while using this medicine.
Q. Can I stop taking Celrim TZ 1000 mg/125 mg Injection when I feel better?
No, do not stop taking Celrim TZ 1000 mg/125 mg Injection and complete the full course of treatment even if you feel better. Your symptoms may improve before the infection is completely cured.
