Manufacturer: Celon Laboratories Ltd
Salt Composition : Tranexamic Acid(500mg)
Vial of 5ml Injection
(Inclusive of all taxes)
Celtranz 500mg Injection is an anti-fibrinolytic. It works by preventing the breakdown of clots which leads to the stoppage of bleeding. This injection must be administered under the supervision of a healthcare professional. You should not take it if you have any known allergy to this injection.
Tranexamic acid is a synthetic derivative of the amino acid lysine and binds the 5 lysine binding sites on plasminogen. This inhibits plasmin formation and displaces plasminogen from the fibrin surface. It may also directly inhibit plasmin and partially inhibit fibrinogenolysis at higher concentrations.
Tranexamic acid 1 g was given intravenously to three healthy volunteers. Plasma concentrations decayed in three monoexponential phases. Most elimination took place during the first eight hours, giving an apparent elimination half-life of approximately two hours. Plasma clearance ranged between 110-116 ml/min.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Celtranz
Tiredness
Nasal congestion (stuffy nose)
Musculoskeletal (bone, muscle or joint) pain
increased risk of blood clotting.
fluid accumulation in the brain.
a clot in the small veins that carry blood to or from the retina of the eye.
a heart attack.
acute blood clot in a blood vessel supplying the lungs.
heart valve disease
Celtranz 500mg Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Celtranz 500mg Injection may cause excessive drowsiness with alcohol.
Celtranz 500mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Menorrhagia. Indicated for the treatment of cyclic heavy menstrual bleeding.
Hereditary Angioedema
Cone Biopsy
Epistaxis
Hyphema
Hereditary Angioedema
Administration.
intravascular clotting.
subarachnoid hemorrhage.
color vision defect.
convulsions.
renal dysfunction.
Kindly do not self administer.
Store below 30°C
If you miss a dose of Celtranz 500mg Injection, skip it and continue with your normal schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Celtranz 500mg Injection helps prevent or reduce heavy bleeding post surgery and in conditions such as heavy periods, dysfunctional uterine bleeding, and nosebleeds.
It is given as a slow injection into a vein.
Your doctor will prescribe the lowest effective dose for the shortest possible time necessary to relieve your symptoms.
Your doctor may monitor your vision regularly while you are taking this medicine.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. Can Celtranz 500mg Injection be given or injected into muscles?
No, Celtranz 500mg Injection should not be administered by injection into the muscles. It should be given strictly through slow injection into the veins to prevent side effects.
Q. Is Celtranz 500mg Injection dangerous?
Every medicine has its own side effects and these side effects are unlikely to happen if taken as directed. Usually, the benefits of the medicine are greater than the risk of side effects. Celtranz 500mg Injection can rarely cause serious side-effects which can be dangerous, like anaphylaxis (red and lumpy skin rash, difficulty breathing, swelling of face, mouth, lips or eyelids), clot in another part of the body or eye problems. Do consult your doctor before you start this medication and follow the instructions strictly as given.
Q. Can Celtranz 500mg Injection cause DVT?
Yes, Celtranz 500mg Injection promotes blood clotting, thereby preventing blood loss. However, in rare cases, this can lead to a chance of developing a clot in the deep leg veins, a condition known as deep vein thrombosis (DVT). Although many research studies have shown that the increased risk of clot can be due to some other additional factors rather than Celtranz 500mg Injection itself. This condition has been found to be more common in female patients taking Celtranz 500mg Injection. Do consult your doctor before you start this medication and follow the instructions strictly as given.
Q. Can Celtranz 500mg Injection affect the colour vision of eyes?
Yes, there are chances of possible disturbances in your colour vision when you are on long term treatment with Celtranz 500mg Injection. Hence, regular eye check should be done during treatment and doctor should be informed if you notice any change in your vision. If any changes are seen your doctor may stop the medicine and suggest an alternative.
Q. Can Celtranz 500mg Injection cause pulmonary embolism?
Celtranz 500mg Injection promotes blood clotting and can rarely cause blood clot to travel to the lungs (pulmonary embolism) which can turn fatal sometimes. Pulmonary embolism is not a common side effect in patients taking Celtranz 500mg Injection but can occur in overdosing, patients with long bedrest or prone individuals. Evidence suggests that the increased risk of clot can be due to some other additional risk factors as well.
Q. Can you take Celtranz 500mg Injection on an empty stomach?
Celtranz 500mg Injection can be taken with or without food with a glass of water. The medicine should be swallowed as a whole and should not be crushed or chewed.
Q. Can I take Celtranz 500mg Injection for more than 5 days?
The dose and duration of this medicine is decided by the type of disease for which it is prescribed. For heavy bleeding during monthly menstruation, it is usually taken for up to 5 days. For other conditions it can be prescribed for less than 5 days and even more that 5 days which is decided by the prescribing physician.
Q. Does Celtranz 500mg Injection affect fertility?
No, Celtranz 500mg Injection does not affect fertility. It is taken for heavy menstrual bleeding and evidence suggests no interference of this medicine with ovulation (release of eggs from the ovaries). Therefore, this medicine is not a type of contraceptive medicine and it will not affect your chances of becoming pregnant.
Q. Can Celtranz 500mg Injection be taken for nose bleeding?
Yes, Celtranz 500mg Injection can be used for nose bleeding. It helps to clot the blood and prevent bleeding. If the bleeding is frequently observed then the medicine can be even taken for a week.
