Manufacturer: Sun Pharmaceutical Industries Ltd
Salt Composition : Paracetamol, Phenylpropanolamine, Cetirizine
Strip of 10 Tablet
(Inclusive of all taxes)
Cerzin Cold Tablet may be prescribed alone or in combination with another medicine. You should take it regularly as advised by your doctor. It is usually best taken with food otherwise it may upset your stomach. Do not take more or use it for longer than recommended.
Cerzin Cold Tablet is a common painkiller used to treat aches and pains. It works by blocking chemical messengers in the brain that tell us we have pain. It is effective in relieving pain caused by headache, migraine, nerve pain, toothache, sore throat, period (menstrual) pains, arthritis, and muscle aches
Paracetamol is readily absorbed from the gastrointestinal tract with peak plasma concentrations occurring about 30 minutes to 2 hours after ingestion. It is metabolised in the liver (90-95%) and excreted in the urine mainly as the glucuronide and sulphate conjugates. Less than 5% is excreted as unchanged paracetamol
The drug was shown to be rapidly absorbed with a mean tmaxof 1.47 ± 0.49 h and a mean elimination half-life of 4.0 ± 0.5 h. Phenylpropanolamine is predominantly excreted via the kidney with a mean renal clearance of 0.646 ± 0.089 liter/kg/h and 90.2 ± 1.7% excreted unchanged in the urine.
The pharmacokinetics of cetirizine have been found to increase linearly with dose across a range of 5 to 60 mg. Its Cmax following a single dose has been found to be 257 ng/mL for 10 mg and 580 ng/mL for 20 mg.
SIDE EFFECTS OF PARACETAMOL
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Cerzin Cold
Nausea
Vomiting
Insomnia (difficulty in sleeping)
Headache
Constipation
Itching
SIDE EFFECTS OF PHENYLPROPANOLAMINE
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Cerzin Cold
Systemic hypertension (high blood pressure)
Nausea
Insomnia (difficulty in sleeping)
Palpitations
SIDE EFFECTS OF CETIRIZINE
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Cerzin Cold
Sleepiness
Fatigue
Vomiting
Dryness in mouth
Headache
Constipation
caloric undernutrition.
acute liver failure.
liver problems.
a condition where the body is unable to maintain adequate blood flow called shock.
acetaminophen overdose.
acute inflammation of the liver due to hepatitis C virus.
overactive thyroid gland.
increased pressure in the eye.
closed angle glaucoma.
high blood pressure.
stenosing peptic ulcer.
blockage of the urinary bladder.
enlarged prostate.
an inability to completely empty the bladder.
Cetirizine is contraindicated in anyone with a known hypersensitivity to it or any of its ingredients. Cetirizine is also contraindicated in anyone with a known hypersensitivity to hydroxyzine, as cetirizine is a metabolite of hydroxyzine
Cerzin Cold Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is unsafe to consume alcohol with Cerzin Cold Tablet.
Information regarding the use of Cerzin Cold Tablet during breastfeeding is not available. Please consult your doctor.
Phenylpropanolamine is a sympathomimetic agonist. It narrows blood vessels in the nose to relieve congestion. Cetirizine is an antiallergic which relieves allergy symptoms like runny nose, watery eyes and sneezing
Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.
Interaction with Alcohol
You should avoid consuming alcohol while taking this medicine. Symptoms like fever, chills, rashes, joint pain and swelling, excessive weakness, nausea should be immediately reported to the doctor.
Interaction with Lab Test
5-HIAA Urine Test
You may get a false-positive result for this test if you take Cerzin Cold Tablet.
Interaction with Medicine
One must take caution while taking this medicine. This medication may interact with other medication like Ketoconazole, Metformin, Anti-hypertensives if administered concomitantly. Also, Barbiturates, carbamazepine, hydantoins, sulfinpyrazone can increase the hepatotoxic potential of acetaminophen; chronic ethanol abuse increases the risk for acetaminophen toxicity; effect of warfarin may be enhanced
Interaction with Food
May slightly delay absorption of extended-release preparations; rate of absorption may be decreased when given with food high in carbohydrates
Interaction with Disease
Patients suffering from liver disease should use some other safer alternative.
Do not chew, crush or break it. Cerzin Cold Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Cerzin Cold Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines
Paracetamol
Paracetamol should be taken with food or milk to prevent upset stomach.
Take it as per the dose and duration prescribed by your doctor. Long term use may lead to serious complications such as stomach bleeding and kidney problems.
Do not take indigestion remedies (antacids) within 2 hours of taking Paracetamol.
Avoid consuming alcohol while taking this medicine as it can increase your risk of stomach problems.
Inform your doctor if you have liver disease as your dose may need to be adjusted.
Your doctor may regularly monitor your kidney function, liver function and levels of blood components if you are taking this medicine for long-term treatment.
Phenylpropanolamine
Do not continue phenylpropanolamine for more than 7 days if your condition does not improve or if you have high fever.
Tell your doctor if you have high blood pressure, heart problems, liver or kidney disease, diabetes, prostate enlargement or visual problems due to increased pressure in the eyes (glaucoma).
Seek immediate medical attention and discontinue medication if you experience difficulty in breathing, sudden swelling or skin reactions, fits, rapid heartbeat or hallucinations.
Use with caution if you are a woman or an elderly patient. Woman may be at a higher risk of haemorrhagic stroke (bleeding in the brain).
Avoid driving or operating machinery if you feel dizzy or drowsy after taking phenylpropanolamine.
Tell your doctor if you are or planning to become pregnant or are breastfeeding.
Do not take if allergic to phenylpropanolamine or any of its ingredients.
Cetirizine
Your doctor has prescribed Cetirizine to help relieve allergy symptoms such as itching, swelling, and rashes.
It's much less likely to make you feel sleepy than other similar medications.
It is okay to take Cetirizine with most other medications as it has few drug interactions.
Use caution while driving or doing anything that requires concentration as Cetirizine can cause dizziness and sleepiness.
Do not drink alcohol while taking Cetirizine as it may cause increased sleepiness.
Stop taking Cetirizine at least three days before taking an allergy test as it can affect the test results.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Cerzin Cold Tablet may be taken with or without food, but it is better to take it at a fixed time.
Q. What if I vomit after taking Paracetamol?
If you vomit in less than 30 minutes after having a dose of Paracetamol tablets or syrup, retake the same dose again. If you vomit after 30 minutes of a dose, you do not need to take another one until the next standard dose.
Q. When will I feel better after taking the Paracetamol?
Usually, you will start feeling better after about half an hour of taking a Paracetamol.
Q. How often can I take the Paracetamol?
You should only take four doses of Paracetamol in 24 hours. There should be a gap of at least 4 hours between two doses. Do not take Paracetamol for more than 3 days without consulting a doctor first.
Q. Does Paracetamol make babies sleepy?
No, Paracetamol does not make babies sleepy. It is a pain-relieving medicine that is also used to control high fever.
Q. Is Paracetamol safe for children?
Paracetamol is considered safe for children only when used as directed by the doctor.
Q. Is Paracetamol an antibiotic?
No, Paracetamol is not an antibiotic. It works as a painkiller and fever-reducing medicine.
Q. Can I take Paracetamol and ibuprofen together?
Ibuprofen and Paracetamol are safe medicines, but both should not be used together. Consult your doctor if you are not sure.
Q. How long does a Paracetamol take to work?
Paracetamol takes around 30-45 min to start working and show its effects. It is advised to take this medicine for the duration suggested by the doctor. Consult your doctor if you experience any bothersome side effects.
Q. What are the serious side effects of taking an excess of the Paracetamol?
Overdose of Paracetamole may cause severe life-threatening liver injury. Taking more than the prescribed dose may also cause kidney injury, decreased platelet count, and even coma. Early symptoms of an overdose include nausea, vomiting, and general tiredness. Immediately consult a doctor or reach an emergency in case of a suspected overdose.
Phenylpropanolamine
Q. Is phenylpropanolamine the same as phenylephrine?
Phenylpropanolamine and phenylephrine are different drugs belonging to the same class of medications (nasal decongestants). Both are used to relieve blocked nose or sinuses caused by common cold and seasonal nasal allergies (hay fever)
Q. Does Phenylpropanolamine cause stroke?
Phenylpropanolamine has shown to increase the risk of hemorrhagic stroke (bleeding in the brain). Women are at a higher risk.
Q. Is Phenylpropanolamine a controlled substance?
Phenylpropanolamine is a controlled substance since it can be used for manufacturing of illegal drugs
Q. Is Phenylpropanolamine still on the market?
Phenylpropanolamine is banned in India due to increased risk of haemorrhagic stroke (bleeding in the brain) and is no longer marketed in India
Cetirizine
Q. Does Cetirizine make you tired and drowsy?
Yes, Cetirizine can make you feel tired, sleepy, and weak. If you have these symptoms, you should avoid driving or operating heavy machinery.
Q. Is Cetirizine a steroid? What is it used for?
Cetirizine is an anti-allergic medication, not a steroid. It relieves the symptoms of allergy. It is used to relieve runny nose, sneezing and redness, itching, and watering of the eyes caused by hay fever or seasonal allergies. It also relieves similar symptoms caused due to allergies to substances, such as dust mites, animal dander, and mold. It is also used to treat symptoms of hives, including itching and rash.
Q. How long does it take for Cetirizine to work?
You will notice an improvement within an hour of taking Cetirizine. However, it may take a little longer to notice the full benefits.
Q. Can I take Cetirizine and Fexofenadine together?
Sometimes the doctor may advise you to take two different antihistamines together if you are being treated for a severe itchy rash. If you are taking Cetirizine during the daytime, your doctor may prescribe another antihistamine for the night which causes sleepiness, especially if the itch makes it difficult for you to sleep. Do not take two antihistamines together unless recommended by your doctor.
Q. For how long should I continue Cetirizine?
The duration for which the medicine needs to be taken depends on the problem being treated. If you are taking it for an insect bite, you may need it for a day or two. Similarly, if you are taking it to prevent symptoms of chronic allergic rhinitis (inflammation of the nose) or chronic urticaria, you may need to take Cetirizine for a longer time. Talk to your doctor if you are unsure about the duration of using Cetirizine.
Q. Is it safe to take Cetirizine daily for a long time?
Cetirizine is safe if used as prescribed by your doctor. Moreover, it is unlikely to harm you if you take it for a long time. But, it is best to take Cetirizine for only as long as you need it.
